Bacterio3

Question 1

Cutibacterium acnes is a gram …. bacterium ,…….(aerobic/anaerobic)that cause the formation of ….

Answer 1

Positive
Anaerobe
Acne vulgaris

Question 2

T or F

Comedones are lesions on skin caused by cutibacteria (blackheads or white heads)

Answer 2

True

Question 3

Cutibacteria multiplies in …. gland and blocks the pore

Answer 3

Sebaceous

Question 4

How to treat acne?

Answer 4

Doxycycline

Question 5

Corynebacteria diphtheriae is from a family called … some are from … and mostly non pathogenic

Answer 5

Diphtheroids

NF

Question 6

The pathogenic form of diphtheriae is gram …,(motile/non),(sporeforming/non) that grows on ……..medium

Answer 6

Positive
Non-motile
Non spore forming
Tellurite Blood

Question 7

Tellurite medium makes the colony appears …. because of the …. granules present in diphtheria

Answer 7

Black
Metachromatic granules (ppi)

Question 8

T or F

Upon gram staining corynebacteria appears like a chinese letter at the edge of the culture and drumstick in the middle.

Answer 8

False

Reversed

Question 9

T or F

Diphtheria is a respiratory infection but also can cause skin infections trasmitted by contact.

Answer 9

True

Question 10

T or F

Diphtheria can cause diseases even if it didn’t secrete diphtheria toxin

Answer 10

False

It should release it to cause the disease

Question 11

Tor F

Diphtheria toxin affects the nucleic acid synthesis in the host cell.

Answer 11

False

Protein synthesis

Question 12

Diphtheria infected people suffers from …. neck and …..-membrane that have white-greyish appearance
We (should/shouldn’t) pull it out.

Answer 12

Bull
Pseudo-membrane
Shouldn’t because the toxin will spread and may cause death

Question 13

How to treat diphtheria ?

Answer 13

Penicillin G+ Anti-diphtheria toxin (IV or IM)

Question 14

Diphtheria toxin can cause … paralysis and this will lead to…..

Answer 14

Soft palate

Suffocation or aspiration

Question 15

Worst case scenario, Diphtheria toxin may cause myocarditis and consequently ……

Answer 15

Heart failure

Question 16

Skin diphtheria sits on skin that has predisposition for…..

Answer 16

Wounds

Question 17

…… is a test used to identify if the diphtheria is toxigenic or not

Answer 17

Elek plate

Question 18

Listeria monocytogenes (anaerobic/facultative anaerobes)….. ,(extracellular/intracellular)…. and (motile/nonmotile)

Answer 18

Fac anaerobes
Fac Intracellular
Motilee (to be seen later)

Question 19

Listeria has 3 modes of transmission :
1-
2-
3-

Answer 19

1- food by ingestion

2- trasmit it transplacentally from mother to child (like agalactiae)
3- during delivery (like agalactiae)

Question 20

…… enrichment medium is used to detect the presence of Listeria monocytogenes

Answer 20

Cold enrichment medium (4 C)

Question 21

After primary bacterimia , Listeria could reach the …..or ….
Thus it’s an (invasive/non-invasive)….. bacteria

Answer 21

Brain or placenta

Invasive

Question 22

Treatment of Listeria monocytogenes

Answer 22

Ampicillin

Question 23

High risk group of infection with LM:
1-
2-
3-
4-

Answer 23

1- immunocompromised ( have higher risk of all infections)
2- pregnant woman after eating undercooked food
3- infants (transplacentally or vaginal during delivery)
4- elderly

Question 24

Non specific Complications cause by LM:

Answer 24

1- fever
2- myalgia
3- arthralgia

Because we see them in other diseases like covid

Question 25

Specific complication caused by LM:

Answer 25

1-septicimia 2-meningitis (it can reach the brain) 3- self limited gastroenteritis

Question 26

..... is a term used when we suffer from gastroenteritis followed by recovering.

Answer 26

Listeriosis

Question 27

When a baby is infected with LM , he is said to be ....... and thus inducing ....... This case is called...

Answer 27

Septic Granulomatosis Granulomatosis infantiseptica

Question 28

T or F | LM is always motile because it has many flagella made from flagellin and it's peritrichous

Answer 28

False Not always motile at some point it uses the actin of the host cell and make flagella from those actin filaments. And become peritrichous

Question 29

LM secretes ..... as a virulence factor (exotoxin) to escape the vacuolar lysis

Answer 29

Listeriolysin O

Question 30

List the modes of transmission of bacillus anthracis

Answer 30

1- by contact 2- by inhalation (woolsorter's disease) 3- by ingestion (causes septic kind of diarrhea)

Question 31

The capsule of bacillus anthacis is made up of .......

Answer 31

Polypeptides

Question 32

The anthrax toxin is made up of ....... parts, each part is encoded by specific gene each present on a....

Answer 32

3 | Plasmid (we have 3 plasmids)

Question 33

The 3 parts of anthrax toxinare called,......,......,....

Answer 33

PA LF EF

Question 34

List the role of each of the following parts: PA LF EF

Answer 34

PA is the protective antigen that binds first and attracts the other 2 LF lethal factor for killing EF edema factor for swelling

Question 35

The colony of bacillus anthracis in a culture media adopts the shape of .....

Answer 35

Medusa's head

Question 36

``` Skin anthrax can consequently leads to : 1- 2- 3- 4- ```

Answer 36

1-papule (elevated skin) 2-vesicle (may) 3-pustule(pus) 4-necrotic lesion

Question 37

Regarding diphtheria, it's not toxigenic unless.......

Answer 37

It was infected by a bacteriophage having diphtheria toxin gene

Question 38

T or F | Regarding LM, it's a bimodal bacteria.

Answer 38

Trueee

Question 39

Bacillus anthracis is a gram.... bacterium, (sporeforming/not).... and (invasive/not)....

Answer 39

Positive Spore forming Not Invasive

Question 40

Regarding black eschar caused by ......, the pustule is said to be (benign/malignant).......

Answer 40

Bacillus anthracis | Malignant

Question 41

....... edema is the edema that surrounds the eschar, it contains viscous fluids rich in .... and have a ..... color.

Answer 41

Gelatinous edema Proteins Red

Question 42

Mediastinitis is a clinical case that is caused by ...... bacteria, after water and blood in the mediastinum compress on the....

Answer 42

Bacillus anthracis | Veins

Question 43

T or F | Human are accidental hosts for bacillus anthracis

Answer 43

True

Question 44

T or F | Antrax can cause hemorrhagic diarrhea

Answer 44

True

Question 45

Bacillus cerues and anthracis are gram... bacteria and (anaerobes/aerobic)...

Answer 45

Positive | Aerobic

Question 46

Bacillus cereus is a (noninvasive/invasive) bacteria...that causes .... that is not an infection

Answer 46

Not invasive | Food poisoning

Question 47

We have 2 strains of cereus: 1- ...... causes vomiting 2- ....... causes diarrhea

Answer 47

Emetic | Diarrheal

Question 48

Emetic strain works on .... of the hypothalamus DIRECTLY and it's found on starchy food left at room temperature for a long period of time where it's toxin becomes heat..., it's incubation period is .... and lasts for...

Answer 48

Vomiting center Stable Less than 6 hours 1 or 2 days

Question 49

Diarrheal strain have (bigger/smaller) ... IP , it's poison is heat ....with an inoculum size .... to cause poisoning with symptoms like .... and.....

Answer 49

Bigger (up to 6) Labile 10^8 Stomach ache and diarrhea

Question 50

Bacillus can cause swelling of the eyeball , this case is called...... and may consequently leads to irreversible ....... because it can also affects the retina.

Answer 50

Panophthalmitis | Blindness

Question 51

T ro F | Diphtheria can cause toxemia

Answer 51

True

Question 52

DT can lead to paralysis of -------- and ------ nerves

Answer 52

Heart | Adrenal

Question 53

Ip for DT

Answer 53

5-10 days (average 1week)

Question 54

Outcomes of LM

Answer 54

Like strep B Abortion or still birth whether early or late Pueperal sepsis on woman

Question 55

Ip for LM

Answer 55

1-90 days

Question 56

T or F | A patient can die from skin anthrax

Answer 56

True

Question 57

T or F | Anthrax can cause hemorrhagic diarrhea but not a septic one

Answer 57

False | Can cause both