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Bacterio6 Flashcards

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1
Q

Salmonella typhimurium causes only ……

A

Gastroenteritis

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2
Q

Salmonella typhimurium have a (broad/narrow) host range

A

Broad

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3
Q

Salmonella typhi lost the …. genes and became host……(narrow or broad), it’s (imvasive or not)……

A

Generalist genes
Host restricted (narrow)
Invasive

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4
Q

Salmonella dublin and cholerasuis are host …….( restricted or adapted), and they are part of …….. of cow and pig respectively.

A

Adapted

NF

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5
Q

Typhoid fever aka….. fever, the specific cell for salmonella infection is the ….. cell crossing it by ……., this will cause hyperplasia of ……..

A

Enteric fever
M cell
Transcytosis
Peyer’s patches

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6
Q

T or F

V.cholera have an inoculum size less than salmonella

A

False

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7
Q

Salmonella affects other organs: ……. and …… , where in the latter it can remain dormant but still can be transmitted

A

Liver and gallbladder

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8
Q

……. appearance on skin is caused by salmonella

A

Rose spots

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9
Q

T or F

We can rely on the appearance of rose spots to diagnose salmonella

A

False

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10
Q

T or F

Salmonella can cause perforation

A

True

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11
Q

How to treat salmonella patients?

A

Ceftriaxone IM

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12
Q

Dessert🧇

The diarrhea in case of enteric fever is called….

A

Pea-soap diarrhea🥲

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13
Q

Sickle cell anemia patients have a higher risk of developing…….. after infection with salmonella

A

Osteomyelitis

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14
Q

T or F

Salmonella can cause constipation

A

True

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15
Q

T or F

Salmonella can cause leukopenia

A

True

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16
Q

Salmonellosis aka….. is caused by two salmonella families …… and……, characterized by …… diarrhea,where we (should/not) give antibiotics because…….

A

Enterocolitis
Typhimurium and enteritidis
Profuse diarrhea
Shouldn’t give because this will increase carriage time

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17
Q

There are 3 types of salmonella vaccine list them

A

Killed vaccine heated
Live (attenuated) Ty21A
Vi vaccine
(killed, attenuated and polysaccharide)

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18
Q

Campylobacter jejuni have a ……. appearance, and ….. flagella, grows on …… medium, grows on (high/low)…… temperature and (aerobic or microaerophilic)…..
The inoculum of campy jejuni is ……

A
  • sea gull apearance or comma
  • 2 flagella each on one side (bipolar)
  • skirrow (vancomycin,polymixin and trimethoprim)
  • high (42)
  • microaerophilic
  • 1000
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19
Q

Source of infection of campylobacter jejuni:….

A

Poultry (meat - chicken and milk)

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20
Q

Symptoms of campylobacter jejuni:

A 
Nausea
Diarrhea (often bloody)
Vomiting
Fever
Most common cause of gastroenteritis in US
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21
Q

T or F

Campylobacter jejuni are not invasive

A

False

Can cause transient bacterimia

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22
Q

…… can cause reactive arthritis (reiter’s syndrome)

A

Campylobacter fetus

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23
Q

T or F

Reiter’s syndrome is cause by campylobacter fetus after bacterimia

A

False

It’s immunopathological ( cross reaction)

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24
Q

T or F

Campylobacter fetus can cause bacterimia especially immunocompromised patients

A

True

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25
Tx of vibrio vulnificus
Doxycycline
26
Vibrio ...... can cause ------- and -------- skin lesions, MR is -------
Vulnificus Septicimia Metastasic 50%
27
T or F | Vibrio paraheamolyticus and vulnificus infections are caused mainly by sea food
True
28
T or F | Vibrio vulnificus causes desentry like syndrome
False
29
T or F | IP for vibrio para. Is long
False | Short
30
T or F | Vibrio parah. Causes a severe gastroenteritis
False | Self limited
31
T or F | Vibrio vulnificus can be caused only through GI
``` False Direct contact ( open wounds + sea water) ```
32
Mode of transmission of V.cholera
Fecal oral
33
T or F | V.cholera is acid labile
True | Grows in basic med ( 8.5-9.5 )
34
V.cholera survives the acidic medium or the stomach by .....
Buffering effect ( usually present with other substances(eg. Water...))
35
``` V cholera charac: ...... shape Ox(.....) Cat (...) Grows on ...... agar Causes ........ stool ...... flagella (Halophilic / thermophilic) ```
``` Comma + + TCBS Rice watery 1 flagellum Halophilic ```
36
T or F | GM1 is the receptor for V.cholera
False | V.cholera toxin
37
T or F | Tx of v.cholera is tertacycline
False
38
Prophylaxis for V.cholera
Tetracycline | Azithromycin or erythromycin for children and pregos
39
Vax for V cholera is ...... and induces (permanent/not)...... immunity
Capsular | Not permanent
40
Modes of transmission of shigella
Fecal oral route | MSM ( man having sex with a man)
41
Shigella causes ....... colitis
Inflammatory
42
Shigella is (invasive/not)......, releases ...... which is a ..... mediated toxin, this toxin inhibits ........ synthesis
Invasive Shiga toxin Chromosomally Protein
43
T or F | Salmonella is the number 1 cause of osteomyelitis in sickle cell anemia patients
True
44
Shigella have (high/low) ........ inoculum, In immunocompromised patients it causes : 1- 2- 3- 4-
``` Low Bacterimia Fever Seizure Rectal prolapse ```
45
Tx for shigella
Ceftriaxone
46
T or F | Shigella have low incubation period
False | No IP
47
T or F | Shigella is a STI
False
48
Shigella causes ....... due to neurotoxicity
Tenesmus
49
T or F | In shigella infections we give anti-diarrheal medications
False
50
Shigella vaccine is called....
No vaccine for shigella
51
Tx of H.pylori
Triple therapy : proton pump inhibitor,amoxicillin and clarithromycin Quadriple : proton pump inhibitor, tertracycline, metronidazole and bismuth
52
List the tests we can use to detect H.pylori
Invasive: Gastroscopy Non-invasive: Serology (IgGs) Stool antigen test Urea breath test
53
T or F | Taking proton pump inhibitors can give a false positive result on urea breath test
False | False negative
54
H.pylori are urease (----) , (motile/non)-------, it's considered as a lifelong (colonization/disease).-------- and secretes exotoxins for ------ attraction
Urease + Motile Colonization PMN
55
H.pylori causes : 1------- 2-------- 3-------- in MALT
Antral gastritis Peptic ulcer disease (PUD) Adenocarcinoma
56
Symptoms caused by H.pylori 1------- 2------- 3-------
Bloating Decreased appetite Bad breath odor
57
How H.pylori remove the mucus allowing the gastric acid to penetrate the tissue and make ulcers?
Binds by adhesins CagA and Vac A Secreting urease that will form ammonia Ammonia will make the neutralize the medium
58
Virulence factor of H.pylori: 1---- 2----- 3--------
1-Flagella to get into mucus 2-Urease to release ammonia and neutralize the medium 3- CagA and VacA
59
List the clues and symptoms of enteric fever
- hepatic necrosis (after bacteremia) - gallbladder inflammation (after bacteremia) - perforation - septicimia and sepsis - hallucination because of fever - clues : constipation and leukopenia
60
In HIV patients typhimurium can cause -------- this show that the infection depends on -----/----- interaction, in elderly it can cause ------ absceses and --------
Enteric fever Germ/host Splenic Aortitis
61
Salmonella can be transmitted by ------ animals like ---------
Exotic | Lizards, turturles and caoti
62
T or F | Gram + can cause sepsis by it's exotoxin
False | By TA
63
T or F | After shigella infection we have temporary immunity against it
False | Premanent
64
Classic and eltor cholera are caused by ------- serotype
O1
65
T or F | Vibrio parahe. Can cause fever
True
66
Diseases caused by sea food (vibrio) are mainly due to -------
Global warming
67
Human are the only hosts for-------
Shigella
68
T or F | Shigella is invasive and causes bacteremia in immunocompetwnt patients
False | No bacteremia
69
T or F | Campylobacter jejuni can cause sepsis
False | Only transient bacteremia

Bacteriology (10 decks)

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