Bacterio7

Question 1

T or F

Pseudomonas can grow on macconkey agar but it’s not an enterobacteriacea

Answer 1

True

Question 2

Pseudomonas belong to the family of ……. and grow on ——

Answer 2

Pseudomonads

Fomites

Question 3

T or F

Pseudomonas is a nosocomial infection

Answer 3

True

Question 4

T or F

Pseudomonas can cause skin infections on intact skin

Answer 4

False

Question 5

Pseudomonas are (aerobic/anaerobic)——(spore forming/not)—– and can live on (high/low) temperatures

Answer 5

Aerobic
Non spore forming
High temp

Question 6

List the virulence factors for pseudomonas

Answer 6

1-alginate Capsule (fluffy slime and biofilms)
2-Pigments (structural virulence factors)(pyorubin,pyomelanin,pyocyanin and pyoveridin)
3- exotoxin A (acts on EF2 like DT)
Exotoxins all sites
LPS
Pilli

Question 7

Role of:
Pyocyanin:
Pyoveridin:

Answer 7

Pyocyanin : release of IL8

Pyover: is a siderophore, transports iron

Question 8

T or F

Pseudomonas secrete exotoxins that affects all sites

Answer 8

True

Question 9

List the 2 resistance mechanisms pseudomonas use with antibiotics

Answer 9

• efflux

- ampC

Question 10

We never treat pseudomonas by 1 antibiotic, list the antibiotics we can use :

Answer 10

Piperacillin
Aztreonam
Imipinem
Meropenem
Ciprofloxacin
Plus ceftazidimee

Question 11

T or F

Pseudomonas is a MDR

Answer 11

True

Question 12

In a nosocomial settings, Pseudomonal infections can cause:
1-
2-
3-
4-
5-
6-

Answer 12

1-pneumonia
2-otitis externa
3-UTIs
4-ecthyma gangrenosum
5- diabetic foot infection
6-keratinisis

Question 13

Diabetic foot infection is ……. harboring pseudomonas and other bacteria

Answer 13

Polymicrobial

Question 14

If the person is ——, otitis externa will be …… and affects the ……. sinus directly behind the ear
should be treated by ….. antibiotics

Answer 14

Diabetic
Malignant otitis externa
Mastoid
PO

Question 15

……. patients have high risk of developing biofilms of pseudomonas especially in repiratory tract

Answer 15

Cystic fibrosis

Question 16

…….. is not caused by the bacteria itself but ofc there is a predisposition, it’s common in ———

Answer 16

Ecthyma gangrenosum

IV drug users

Question 17

Pseudomonas is cat(—) oxidase(—)

Answer 17

Positive positive

Question 18

Acinetobacter baumanni is a …… infection and strong …… maker just like pseudomonas, it’s cat(—-) ox(—-)

Answer 18

Nosocomial
Biofilm
Cat + ox -

Question 19

Regarding drug resistance, acinetobacter is …..

Answer 19

MDR
XDR
PDR

Question 20

What type of nosocomial settings can cause infection with acinetobacter

Answer 20

Mechanical ventilation
Post neurosurgery
Intravascular devices

Question 21

T or F

Percentage of mortality in patients infected with acinetobacter is 60%

Answer 21

False

90%

Question 22

Yersinia is a ……. bacteria (change it’s shape) and prt of …….. have …… appearance on staining by ….. or wayson’s dyes

Answer 22

Pleiomorphic
Enterobacteriaceae
Bipolar pin
Giemsa

Question 23

T or F

Yersinia pestis is considered zoonotic

Answer 23

True

Question 24

Yersinia pestis is (aerobic/anaerobic)——- and (intracellular/extracellular)——-

Answer 24

Facultative anaerobes

Facultative intracellular

Question 25

T or F | Humans are accidental hosts for yersinia pestis

Answer 25

True | Dead end hosts

Question 26

T or F | Yersinia pestis can cause pneumonic plague (transmitted thru inhalation)

Answer 26

True

Question 27

V and W antigens found in yersinia pestis are resposible for

Answer 27

Escaping intracellular killing

Question 28

When yesrsinia pestis enters the body , a .......protein called ..... will be activated, this will act as an antagonist of ........ found in flea.

Answer 28

Yersinia pestis Capsular Fraction I Plasminogen activating protease (coagulase)

Question 29

Host cells for yersinia pestis are :

Answer 29

PMN | Macrophages

Question 30

Swelling of the lymph nodes caused by yersini pestis is called...... and eventually will lead to.......

Answer 30

Buboes | Necrotic LN

Question 31

Transmission of yersinia pestis by inhalation will cause......

Answer 31

Hemorrhagic pneumonia

Question 32

T or F | Yersinia pestis can lead to meningitis

Answer 32

True

Question 33

T or F | Yersinia pestis can cause septicemia

Answer 33

True

Question 34

Tx of yersinia pestis

Answer 34

Streptomycin (aminoglycoside)

Question 35

T or F | The tissue can't die from raptured buboes

Answer 35

False

Question 36

T or F | Yersinia can't cause hemorrhagic mediastinitis

Answer 36

False

Question 37

T or F Primary pneumonic plagues , the patient gets it in the lungs directly Most probably he developed buboes

Answer 37

False | Almost no buboes in primary pneumonic plagues

Question 38

Yersinia pestis have ....... IP

Answer 38

Short

Question 39

Yersinia enterocolitica and pseudotuberculosis are transmitted ........, causes ..... rarely......

Answer 39

Fecal orally Enterocollitis Bacterimia

Question 40

Enterocolitica and pseudotuberculosis can cause inflammation of lymph nodes on mesentery a case called........., found mostly in -----and if it's close to the ileum we call it .....

Answer 40

Mesenteric adenitis Children Terminal illeitis

Question 41

T or F | Yersinia pestis can cause bloody diarrhea

Answer 41

False | Entercolitica

Question 42

T or F | Yersinia enterocolitica and pseudotuberculosis can cause appendicitis

Answer 42

True

Question 43

Yersinia enterocolitica are detected on ....... because it's an enterobactriacea

Answer 43

Macconkey agar

Question 44

T or F | Yersinia enterocolitica can be found in blood donations after the donor has developed bacterimia

Answer 44

True

Question 45

Yersinia enterocolitica and pseudotuberculosis have (high/low) ------ inoculum

Answer 45

High

Question 46

Enterocolitica grow on a ......... medium

Answer 46

Cold enrichment

Question 47

Yerseniosis is a ....... disease

Answer 47

Diarrheal

Question 48

T or F | Pseudomonas can cause systemic diseases (eg. bacteremia)

Answer 48

True

Question 49

Urea breath test is mainly done to ----------

Answer 49

Confirm the eradication of H.pylori