Barrett's Oesophagus

Question 1

Description?

Answer 1

This is a complication of long term oeosphageal reflux

Question 2

Most common in…?

Answer 2

Caucasian men over 50 years

Question 3

Pathology

Answer 3

Prolonged exposure to gastric acid causes the normal squamous stratified epithelium of the oesophagus to be replaced by columnar epithelium
This is a form of intestinal metaplasia

Question 4

What is it called when the epithelium is replaced by a different type?

Answer 4

Metaplasia

Question 5

Describe the oesophagus appearance in Barrett’s?

Answer 5

Red and Velvety

Question 6

Complications of Barrett’s Oesophagus?

Answer 6

Carries the risk of developing into Oesophageal adenocarcinoma

Question 7

What is it called when the cells become cancerous

Answer 7

Dyplasia

Question 8

Treatment

Answer 8

Can’t be reversed
Can treat symptoms same way as GORD
PPIs, Antacids, Lifestyle Changes

Question 9

Symptoms?

Answer 9

Heartburn
Retrosternal Chest pain, worse after eating
Worse on lying down

Question 10

Investigations?

Answer 10

Endoscopy
Biopsy (Check for cancer)