Crohn's Disease Flashcards
1
Q
Describe Crohn’s disease?
A
Chronic inflammation of the GI tract that can affect anywhere from mouth to anus
2
Q
Who does Crohn’s most commonly present in?
A
Young Patients
Males
3
Q
Describe the pathology of Crohn’s?
A
Presents as ‘skip lesions’
Non-continious inflammation in patches
4
Q
Symptoms
A
Diarrhoea Abdominal Pain Weight Loss Failure to thrive in children Fever, Malaise, Anorexia Constipation
5
Q
How can Crohn’s present?
A
Presents acutely or chronically
6
Q
Signs of Crohn’s on inspection?
A
Abdominal Tenderness Right Illiac Fossa Mass Perianal Fistulas and Abscesses Cobblestoning Clubbing
7
Q
Investigations for Crohn’s?
A
Endoscopy and Biopsy Barium Swallow Blood Tests (WWC increased, HB decreased)
8
Q
Describe the histology of Crohn’s?
A
Chronic Inflammatory Cell Infiltrate
Large, non-caesating granulmonas
Patchy chronic active colitis
9
Q
Treatment for Crohn’s?
A
Steroids
Antibiotics
Immunosuppression (Methotrexate)
Surgery
10
Q
Describe surgery for Crohn’s?
A
Only a part of the Colon is resected in surgery
11
Q
Complications of Crohn’s?
A
Malabsorption Short Bowel Syndrome (From Resections) Vitamin Deficiency Gallstones Fistulas Anal Disease Bowel Obstruction Perforation Malignancy
