Block 3 Phys Flashcards Preview

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Flashcards in Block 3 Phys Deck (306)
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1

ADH V1 receptor is

alpha q-- smooth muscle

2

ADH V2 receptor is

alpha s -- kidney

3

90% of filtered water is reabsorbed in the _____ tubule by _______

proximal
AQP1

4

only AQP responsive to ADH

AQP2

5

How does water leave the basolateral membrane of the collecting duct?

AQP 3&4

6

Which is more sensitive to dehydration (leading to AVP release) baroreceptors or osmoreceptors?

osmoreceptors

7

which neurons sends hormones to the posterior pituitary?

magnocellular

8

somatostatin stimulates the release of what hormone from anterior pituitary?

GH

9

AVP and oxytocin are made in what hypothalamnic nuclei?

SON and PVN

10

Ca-calmodulin activates ________

MLCK

11

what is SIADH

syndrome of inappropriate ADH secretion

12

bad taste in mouth is a symptom of what syndrome?

SIADH

13

decreased ADH release is often a complication of

diabetes insipidus

14

anterior pituitary is derived from _____derm

ecto

15

the 3 glycoprotein hormones of the anterior pituitary

TSH FSH and LH

16

all 3 glycoprotein hormones of the anterior pituitary have similar __ subunits and dissimilar ___ subunits

-alpha
-beta

17

pro-opiomelanocortin is cleaved into what hormones

ACTH, beta endorphin, alpha/beta/gamma melanocyte stimulating hormones

18

Growth hormone release is stimulated by _____glycemia and suppressed by ____glycemia

-hypo
-hyper

19

major players in GH release

GHRH and ghrelin

20

minor regulators of GH release

acetylcholine, alpha-adrenergic agonists, dopamine, serotonin

21

GH release is inhibited by

somatostatin and IGF-1

22

a long term increase in GH has what effect on adipose tissue?

anti insulin effect

23

laron's syndrome

GH resistance

24

low GH in adults is associated with

CV risk and muscle loss

25

Hypothalamus controls prolactin by maintaining inhibitory tone via

dopamine

26

Prolactin requires what other 2 things for milk production

insulin and cortisol

27

Long term increases in prolactin lead to

infertility and gonadal dysfunction

28

Increase in prolactin leads to decreases in what hormones?

LSH, FSH, gonadal steroidogenesis, estrogen, testosterone, progesterone

29

What inhibits release of TSH from anterior pituitary?

dopamine, somatostatin, and high levels of glucocorticoids

30

Thyroglobulin is made in _______. Then it's ______ residues are iodinated in the colloid

thyroglobulin
tyrosine