Blood Flashcards Preview

5240 Intro to Biomed > Blood > Flashcards

Flashcards in Blood Deck (25):
1

What are functions of blood?

Transportation( Oxygen, CO2), Regulation (Temp, pH), and protection (WBC, Platlets)

2

What is the average blood volume, Temperature, and pH?

Volume=4-6 Liters
Temp= 38 degrees C, or 100.4 F
pH= Slightly Alkaline (7.35-7.45)

3

What percentage of blood is Plasma, Buffy Coat, and Erythrocytes?

Plasma=55%
Buffy Coat=1%
Erythrocytes=45%

4

What is Hematocrit?

Percentage of blood volume made of red blood cells.

5

What is blood doping?

Donating RBC to yourself.

6

What are the plasma proteins, in order from most numerous to least? What is their function?

1. Albumins (transport substances)
2. Globulins (Antibodies)
3. Fibrinogens (Fiber to clot)
4. Regulatory Proteins (Hormones)

7

What are the characteristics of Erythrocytes?

No nucleus, Biconcave discs, Filled with Hemoglobin, Can bend and flex.

8

What are rouleaux?

Stack of RBC in single line.

9

What is the Erythrocyte lifecycle?

1. Born in red bone marrow
2. Circulate for 120 days
3. Aged RBC are recycled in Spleen and Liver

10

What is Erythropiesis? Occurs where and stimulated by what?

Red blood cell formation. Occurs in red bone marrow. Stimulated by EPO.

11

What is Polycythemia? Anemia?

Polycythemia: Too many RBC
Anemia: Too few RBC

12

Type A, B, AB, and O Blood cells have which antigens? Antibodies?

A: Antigen A, Anti-B antibodies
B: Antigen B, Anti-A antibodies
AB: Antigen A&B, no antibodies
O: No antigen, Anti-A&B antibodies

13

Universal donor? Universal Recipient?

Donor: O
Recipient: AB

14

Rh positive and negative description. Antibodies?

Rh positive=Have Rh factor.
Rh negative= No Rh factor.
Can only have antibodies Rh if you have previously been exposed to Rh factor antigens.

15

What is Erythroblastosis Fetalis?

When the mother is Rh- and baby is Rh+ and mother has Rh Antibodies, mothers WBC will attack babies RBC.

16

What is agglutiniation?

When opposing antibodies come in contact with antigens, they hold on and clump cells together.

17

What are Leukocytes? What are their characteristics and functions?

White blood cells.
C: No hemoglobin, Contains nucleus and organelles
F: Immune response, remove toxins/waste, attack abnormal cells.

18

What is Diapedesis? Chemotaxis?

1. Diapedesis: WBC leace bloodstream to enter tissue
2. Chemotaxis: WBC send signals to attract other WBC

19

What are the two classes of Leukocytes, an which fall into those two categories?

1. Granulocytes: Eosinophil, Neutrophil, Basophil.
2. Agranulocytes: Lymphocyte, Monocyte.

20

What is the mnemonnic for Leukocyte cell, larger percentage to least?

Never Let Monkeys Eat Bananas

21

What are the 3 lymphatic cells, and what do they do?

1. B-lymphocytes: Turn into Plasma and make antibodies
2. T-Lymphocytes: Attack cells directly
3. Natural Killer Cells: Detect/Destroy abnormal cells

22

What is Leukopoeisis? Produced from what two cell types, and produces what?

WBC production
1. Myeloid Stem cells: All cells except lymphocytes
2. Lymphoid Stem Cells: production of lymphocytes

23

Where do B-Lymphocyte cells mature? T?

B=Bone marrow
T=Thymus

24

What are Thrombocytes? How long do they live?

Platelets. Live for 8-12 days

25

What is Hemostasis? What are the phases?

Cessation of bleeding
1. Vascular (vascular constriction)
2. Platelet (temporary patch)
3. Coagulation (Fibrin makes stronger clot)
4. Clot Retraction (Tightens up to close damage)