Blood Lecure 1 / Ch 6 Leukocytes of Lymphoid Heritage

Question 1

T and B Lymphocytes

Answer 1

• They add specificity to the 
   immune systems attack
• Destroying infected cells to 
   prevent spread of virus
• Retaining a memory of 
   exposure to specific
   antigens

Question 2

Location of T Lymphocytes ?

Answer 2

• Originate in Bone Marrow
• Maturation in the Thymus
• Once matured, live in the Lymph Nodes,
  Spleen, & Tonsils. Here they wait, for APC
  to introduce them to antigens.

Question 3

Location of B Lymphocytes

Answer 3

• Maturation in the Bone Marrow
• Live in the Lymphatic nodes & ducts, here
  they wait for antigen.
• Once stimulated by antigen they proliferate
  and become Plasma Cells

Question 4

Plasma Cells

Answer 4

• Capable of producing immunoglobulins
  (antibody) to coat the specific antigen
  – Live a few days to weeks

Question 5

Platelets

Answer 5

• AKA Thrombocytes
• Enucleated
• Vital in hemostasis by coagulation

Question 6

Platelet Life Span

Answer 6

- Develop in Bone Marrow from 
  Megakaryocytes.
- Circulate intravascularly 
- migrate into the  spleen and spend some 
  time here before returning to the 
  bloodstream.
- 9 to 12 days 
-

Question 7

Retention of 1/3 of the platelets in the spleen is called what ?

Answer 7

Sequestration

Question 8

Un-activated Platelet Shape

Answer 8

Small spheres

Question 9

Activated Platelet Shape

Answer 9

round spheres with extended

pseudopods and spikes

Question 10

Platelet Quantity

Answer 10

Normal = 150,000 - 450,000 / μL

Question 11

Thrombocytosis

Answer 11

(AKA: thrombocythemia) Increased number of platelets.

Question 12

Thrombocytopenia

Answer 12

Decreased number of platelets.

Question 13

Testing platelets after CPB. Platelet count is not a good test, Platelet aggregation is a better test. POC tests are faster because?

Answer 13

They use whole blood

Question 14

HIT

Answer 14

Heparin induced Thrombocytopenia

Question 15

HITT

Answer 15

Heparin induced thrombocytopenia and

thrombosis