Flashcards in Blood Lecure 1 / Ch 6 Leukocytes of Lymphoid Heritage Deck (15)
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1
Q
T and B Lymphocytes
A
• They add specificity to the immune systems attack • Destroying infected cells to prevent spread of virus • Retaining a memory of exposure to specific antigens
2
Q
Location of T Lymphocytes ?
A
- Originate in Bone Marrow
- Maturation in the Thymus
- Once matured, live in the Lymph Nodes,
Spleen, & Tonsils. Here they wait, for APC
to introduce them to antigens.
3
Q
Location of B Lymphocytes
A
- Maturation in the Bone Marrow
- Live in the Lymphatic nodes & ducts, here
they wait for antigen. - Once stimulated by antigen they proliferate
and become Plasma Cells
4
Q
Plasma Cells
A
- Capable of producing immunoglobulins
(antibody) to coat the specific antigen
– Live a few days to weeks
5
Q
Platelets
A
- AKA Thrombocytes
- Enucleated
- Vital in hemostasis by coagulation
6
Q
Platelet Life Span
A
- Develop in Bone Marrow from Megakaryocytes. - Circulate intravascularly - migrate into the spleen and spend some time here before returning to the bloodstream. - 9 to 12 days -
7
Q
Retention of 1/3 of the platelets in the spleen is called what ?
A
Sequestration
8
Q
Un-activated Platelet Shape
A
Small spheres
9
Q
Activated Platelet Shape
A
round spheres with extended
pseudopods and spikes
10
Q
Platelet Quantity
A
Normal = 150,000 - 450,000 / μL
11
Q
Thrombocytosis
A
(AKA: thrombocythemia) Increased number of platelets.
12
Q
Thrombocytopenia
A
Decreased number of platelets.
13
Q
Testing platelets after CPB. Platelet count is not a good test, Platelet aggregation is a better test. POC tests are faster because?
A
They use whole blood
14
Q
HIT
A
Heparin induced Thrombocytopenia
15
Q
HITT
A
Heparin induced thrombocytopenia and
thrombosis
