Name 3 Thrombolytic Medications ?
Streptokinase
Pro-Urokinase
TPA
Drugs or enzymes that act on pre-existing thrombi. They work by activating the fibrinolytic pathway, converting plasminogen to plasmin.
Thrombolytics
Name 2 Anti-Thrombolytics ?
- Epsilon Amino Caproic Acid (EACA)
- Tranexemic Acid
Blocks the conversion of plasminogen to plasmin by binding to sites of plasminogen.
Anti-Fibrinolytics
What medications prevent aggregation ?
Aspirin
Plavix
Effient
What medication inhibits Cyclooxygenase ?
Aspirin
What 2 medications bind to the P2Y12 receptors on the platelets ?
Plavix
Effient
Name 6 Direct Thrombin Inhibitors ?
Hirudin r-hirudin Lepirudin Bivalirudin Argatroban Pradaxa
What are 2 Direct Thrombin Inhibitors that are approved to treat patients with HIT ?
Hirudin
Argatroban
Name 2 Xa Inhibitors ?
Xarelto (rivaroxaban)
Eliuis ( apixaban)
What would your prescribe a patient for treatment of DVT and PE ?
Xa Inhibitor
Xarelto (rivaroxaban)
No antidote
What mediation is used for prevention of stroke in Non-Valvular Atrial Fibrillation?
Xa Inhibitor
Eliquis (apixaban)
Name 4 LMWH ?
Nadroparin calcium - Fraxiparin
Enoxaparin sodium – Lovenox
Fondaparinux - Arixtra
Dalteparin – Fragmin
What medication is made from fish sperm and can cause anaphylaxis for patients with fish allergies?
Protamine
What medication Inhibits vitamin K dependent factors (II, VII, IX, X, protein C, and protein S).
Coumadin (Warfarin)
