Blood & Lymphatic Systems Flashcards

(55 cards)

0
Q

Granulocytes

A

Category of Leukocytes (WBCs) characterized by the presence if granules in their cytoplasm.

Have various nucleus shapes

-neutrophils, eosinophils, & basophils

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1
Q

What is Hematocrit? How can it change?

A

Percent of RBC’s to total volume of blood.

It can change if you move somewhere with less oxygen & your body recognizes this & starts making more RBCs. Opposite happens if you move to low elevation.

Female: 37-48%
Male: 45-52%

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2
Q

Agranulocytes

A

Category of Leukocytes (WBCs) with the absence of granules in cytoplasm.

One shape of nucleus

-lymphocytes & monocytes

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3
Q

Neutrophils

A

Destroy bacteria & release anti-microbial chemicals.

Increase in # caused by:

  • infection
  • stress
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4
Q

Eosinophils

A

Destroys Ag - Ab complexes & parasites.

Increased # caused by:

  • allergies
  • autoimmune disease
  • toxins
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5
Q

Basophils

A

Release seratonin, histamine, & heparin which help increase inflammatory response.

Increase in # cause by:

  • allergies
  • disease
  • infections
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6
Q

Lymphocytes

A

T-Cells destroy cancer cells, foreign cells & infected cells.
B-Cells create antigens to make an immune memory.

Increased # caused by:

  • cancer
  • infection
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7
Q

Monocytes

A

Become macrophages & clean up antigens & waste materials.

Increase # caused by:

  • leukemia
  • infections
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8
Q

Functions of Blood

A
  • transportation
  • protection
  • regulation
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9
Q

Blood Transportation

A

Transports hormones, waste, O2/CO2, heat & nutrients to & from organs & cells.

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10
Q

Blood Protection

A

Blood destroys cancer cells, neutralizes toxins, & clots.

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11
Q

Properties of Blood

A
  • Ph levels
  • Viscosity
  • Osmolarity
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12
Q

Blood Ph

A

7.35-7.45 (normal) slightly basic

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13
Q

Blood Viscosity

A

Resistance to flow

Blood is 4.5-5.5 thicker than water

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14
Q

Blood Osmolarity

A

Molar concentration of dissolves particles in one liter of water

Important for waste to be removed & nutrients brought to cell

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15
Q

Formed Elements

A
  • Erythrocytes (RBC)
  • Thrombocytes/Platelets
  • Leukocytes (WBC)
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17
Q

Plasma

A

Clear ECF

Consists of proteins, enzymes, nutrients, waste, hormones, & gases.

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18
Q

Serum

A

Plasma without clotting protiens

Found within plasma

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19
Q

Plasma Protiens

A
  • Albumin
  • Globulins
  • Fibrogen
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20
Q

Albumin

A

Smallest & most abundant protein within plasma

Responsible for movement of water back into the capillary beds

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21
Q

Globulins

A

Help make antibodies to protect you from getting sick

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22
Q

Fibrogen

A

Starts blood clot

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23
Q

Erythropoiesis

A

Production of RBCs

Too many: blood too thick

24
Q

What is the shape of a red blood cell? Why is it important?

A

Bi-Concaved Disc

Important because it increases surface area to drop off O2 and pick up CO2.

25
Hemoglobin
Gives RBCs their color Contains 4 globulin molecules, which each carry 1 O2 molecule. 1 hemoglobin molecule = 4 O2 molecules
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Blood Clotting Cascade
- Extrinsic Pathway | - Intrinsic Pathway
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Extrinsic Pathway
Damaged tissue promotes clotting Completes common pathway in seconds
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Intrinsic Pathway
Damaged endothelial cells promote clotting (no tissue damage required) Completed common pathways in minutes
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Hemostatis
Control/stopping of bleeding (coagulation)
30
3 Steps of Hemostasis
1. Platelet Adheration 2. Platelets Release RXN 3. Platelet Plug Forms
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Platelet Adheration
Platelets stick to damaged blood vessel & then vessel constricts
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Platelets Release RXN
Stuck platelets extend appendages to communicate & release vesicles.
33
Platelet Plug Forms
Released ADP causes other platelets to get stuck to the "net"
34
Blood Type A
A antigen & Anti-B antibody Can receive blood from: -Type A & Type O
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Blood Type B
B antigen & Anti-A antibody Can receive blood from: -Type B & Type O
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Blood Type AB
Both A & B Antigens NO Antibodies Universal Recipient- Can receive blood from ALL blood types
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Blood Type O
Neither A or B Antigens Both A & B Antibodies Universal Donor- can give blood to anyone, but can ONLY receive Type O
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Antigen
Combination of PRO's, glycoproteins, & glycolipids that tell our body if a cell is an antigen
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Antibodies
Gamma globules that are produced by immune cells to bind to foreign substances.
40
Positive Blood Type
You have Rhesus protien
41
Erythrocytes Disorders
- Polycythemia - Sickle-Cell Disease - Anemia
42
Polycythemia
Excess RBC creating high blood viscosity.
43
Sickle-Cell Disease
Hereditary Hemoglobin causes blood clots
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Anemia
Decrease in RBCs - Nutritional Anemia - Iron-deficiency Anemia - Pernicious Anemia
45
Hemophilia
In ability to clot blood
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Leukemia
Cancer of the WBCs
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Type of Antibodies
- IgA - IgD - IgE - IgG - IgM
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IgA
Prevents pathogens from adhering to epithelial and penetrating tissue
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IgD
Acts as an Ig receptor
50
IgE
Stimulates mast cells, pasophils, and eosinophils to tell them there is a problem
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IgG
Makes up 75-85% of Ab's ONLY Ab that crosses the placenta & provides immunity to the fetus
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IgM
Largest of all antibodies Strong agglutinating ability Includes anti-A & anti-B
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Primary Response
IgM Body has not seen particular Antigen before & needs time to build up defense.
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Secondary Response
IgG Body had a prior exposure to the Ag before and can build up defense quickly.
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Hemopoiesis
Production of the formed element if blood - stem cell: can become any type of cell - RBC: no nucleus - WBC: have nucleus