Glucose metabolism Flashcards

(33 cards)

0
Q

Bridge

A

-2 separate Pyruvic acids are oxidized and become acetyl coenzyme A & acetyl coenzyme A2.

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1
Q

Glycolysis

A

-1 glucose molecule breaks down into 2 Pyruvic Acids (6C–>3C)

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2
Q

Krebs

A

-Both Acetyl Coenzymes are stripped of their hydrogen protons & electrons. -all that is left of the sugar is CO2 and H2O (exhale).

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3
Q

How many total ATP are gained from Glycolysis? How?

A

8 total

  • (2ATP–>2ADP) + (4ADP–>4ATP)= 2
  • (2NAD+ –>2NADH+H)= 6
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4
Q

How many ATP are gained from Bridge?

A

6 total

-2NAD+ –> 2NADH+H = 6

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5
Q

How many ATP are gained from the Krebs step?

A

24 total

  • 6NAD+ –> 6NADH+H = 18
  • 2ADP –> 2ATP = 2
  • 2FAD–> 2FADH+ = 4
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6
Q

How many ATP are in each NADH+H?

A

3 ATP

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7
Q

How many ATP are in each FADH+?

A

2ATP

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8
Q

Where is Glycolysis located?

A

Outside the mitochondria, within the cytoplasm.

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9
Q

Where does the Bridge step take place?

A

Inside the mitochondria

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10
Q

Where does the Krebs step take place?

A

Inside the mitochondria

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11
Q

Aerobic

A

O2 required

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12
Q

Anaerobic

A

O2 not required

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13
Q

Where specifically is oxygen used and why?

A

Oxygen is used specifically in the bridge and krebs stages to oxidate the carbon atoms. That is how CO2 is released.

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14
Q

Oxidation

A

The combination of a substance with oxygen

Reaction in which the atom in an element loses an electron and the valence shell increases

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15
Q

Reduction

A

A decrease in positive valence or an increase in neg valance.

Hydrogen combines with a compound

Oxygen is removed from a compound

16
Q

Substrate Level Phosphorylation

A

Only occurs in glycolysis & Krebs.

ADP –> ATP

17
Q

Oxidative Phosphorylation

A

Occur in all 3 steps

Anytime NADH+H or FADH+ are used to create ATP

18
Q

Hydrolysis/Dehydration Synthesis

A

Chemical breakdown on a compound due to reaction with water.

Occurs anytime there is a chemical breakdown, but you can’t see it in te diagram.

19
Q

ATP Synthase

A

Synthesizes ATP

Only allows hydrogen protons through

Comes from ADP & phosphate

20
Q

Chemiosmosis

A

Proton moves across a mitochondrial membrane and ATP synthesis pumps metabolites across a membrane.

(Generation of ATP through hydrogen ions across a membrane. )

21
Q

Beta Oxidation

A

Catabolism of fatty acids in which the fatty acid chain is shortened by successive removal of two carbon fragments from the carboxyl end of the chain.

22
Q

Gluconeogenesis

A

Synthesizes glucose in the liver

23
Q

Glycogenolysis

A

The hydrolysis of glycogen to glucose

24
Glycogenesis
Formation of glycogen from sugar
25
Glycogen
Polysaccharide that stores glucose
26
Glucose
Simple sugar
27
What condition would cause lactic acid to build up?
Cells don't receive enough oxygen >> pH levels drop >> cells metabolize creating lactae
28
Sodium Potassium Pump
2k- in 3Na+ out
29
What does the Electron Transport Chain do? Where is it located?
Located in the inner membrane of the mitochondria. Sorts electrons and protons carried in by NADH+H and FADH+
30
Malate Shuttle
Cells of the liver, kidneys, and heart use this resulting in 3 ATP from each NADH
31
Which cells yield 36 ATP?
Skeletal & Nervous
32
Which cells yield 38 ATP?
Kidney, liver, & heart