Glucose metabolism Flashcards
(33 cards)
Bridge
-2 separate Pyruvic acids are oxidized and become acetyl coenzyme A & acetyl coenzyme A2.
Glycolysis
-1 glucose molecule breaks down into 2 Pyruvic Acids (6C–>3C)
Krebs
-Both Acetyl Coenzymes are stripped of their hydrogen protons & electrons. -all that is left of the sugar is CO2 and H2O (exhale).
How many total ATP are gained from Glycolysis? How?
8 total
- (2ATP–>2ADP) + (4ADP–>4ATP)= 2
- (2NAD+ –>2NADH+H)= 6
How many ATP are gained from Bridge?
6 total
-2NAD+ –> 2NADH+H = 6
How many ATP are gained from the Krebs step?
24 total
- 6NAD+ –> 6NADH+H = 18
- 2ADP –> 2ATP = 2
- 2FAD–> 2FADH+ = 4
How many ATP are in each NADH+H?
3 ATP
How many ATP are in each FADH+?
2ATP
Where is Glycolysis located?
Outside the mitochondria, within the cytoplasm.
Where does the Bridge step take place?
Inside the mitochondria
Where does the Krebs step take place?
Inside the mitochondria
Aerobic
O2 required
Anaerobic
O2 not required
Where specifically is oxygen used and why?
Oxygen is used specifically in the bridge and krebs stages to oxidate the carbon atoms. That is how CO2 is released.
Oxidation
The combination of a substance with oxygen
Reaction in which the atom in an element loses an electron and the valence shell increases
Reduction
A decrease in positive valence or an increase in neg valance.
Hydrogen combines with a compound
Oxygen is removed from a compound
Substrate Level Phosphorylation
Only occurs in glycolysis & Krebs.
ADP –> ATP
Oxidative Phosphorylation
Occur in all 3 steps
Anytime NADH+H or FADH+ are used to create ATP
Hydrolysis/Dehydration Synthesis
Chemical breakdown on a compound due to reaction with water.
Occurs anytime there is a chemical breakdown, but you can’t see it in te diagram.
ATP Synthase
Synthesizes ATP
Only allows hydrogen protons through
Comes from ADP & phosphate
Chemiosmosis
Proton moves across a mitochondrial membrane and ATP synthesis pumps metabolites across a membrane.
(Generation of ATP through hydrogen ions across a membrane. )
Beta Oxidation
Catabolism of fatty acids in which the fatty acid chain is shortened by successive removal of two carbon fragments from the carboxyl end of the chain.
Gluconeogenesis
Synthesizes glucose in the liver
Glycogenolysis
The hydrolysis of glycogen to glucose