Flashcards in Bone: Anatomy, Formation, Growth Plate Disorders, Maturation Disorders Deck (30):
Significance of gray/ white marrow?
Pathologic, fibrotic tissue!
Difference between haverisan canals and volkmann canals?
Haversian= parallel to the long axis of the bone
volkmann canals= perpendicular to the long axis of the bone
What is organic bone matrix made of?
Type I collagen
What cells produce osteoid?
What is the mineralization lag time?
12 days between when osteoid is deposited and it is mineralized
What can inhibit osteoclastic activity?
What is the "bone remodelling unit"?
Osteoblast and osteoclast
Which bone is more rapid and less arranged...lamellar or woven?
What is the structure of the growth plate?
Reserve/ resting zone
Zone of calcification
Zone of ossification
What is morquio syndrome?
mucoplysaccharide deposition in chondricytes tha leads to dwarffism , dental defects and mental retardation
What is found in the urine of someone with morquio syndrome?
What condition results from a vitamin C deficiency?
it is a problem with collagen cross linking and osteoblastic function leading to impaired bone growth
abnormal lateral curvature of the spine?
abnormal anteroposterior curvature of the spine?
One limb's growth plate is stimulated to undergo rapid and prolonged endochorndial ossification (one limb is longer)?
Erhlenmeyer flask deformity is associated with...
Which is the mildest phenotype of OI?
Which form of OI is usually fatal in utero or at birth?
Which is the progressive, most severely deforming OI?
What is the difference between type I and type IV OI?
Type IV has normal sclera (not blue)
What us endrochromatosis?
tumor like masses of abnormally arranged hyaline cartilage
What is Muffacci Syndrome?
Multiple enchondromas and cavernnous/ spindle cell hemangiomas
What day after a fracture is hemorrhage and clot formation seen?
What day after a fracture is earliest new bone seen?
Reparative phase has _______ ossification.
What is psuedoarthrosis?
formation of joint like tissue due to continued movement at a nonunion fracture site
What is Legg- Calve- Perthes disease?
osteonecrosis in the femoral head of children
What is fibrodysplasia ossificans?
massive deposits of bone around many joints
Difference between heterotropic ossification and heterotropic calcification?
bone deposition vs calcium deposition outside of the skeleton