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Pathology Unit 5 > Metabolic: Obesity > Flashcards

Flashcards in Metabolic: Obesity Deck (21):
1

"energy expended at complete rest. lying down in the postabsorptive state"

BMR

2

BMR accounts for what % of TDEE?

60%

3

What organ is the central homeostatic controller of body weight?

the brain

4

What section of the brain processes external signals and manages energy balance?

arcuate nucleus of the hypothalamus

5

"appetite stimulating peptides"

orexigenic

6

"appetite inhibiting peptides"

anorexigenic

7

Orexigenic or anorexigenic?

ghrelin

orexigenic

8

Orexigenic or anorexigenic?

NPY

orexigenic

9

Orexigenic or anorexigenic?

POMC

Anorexigenic

10

Orexigenic or anorexigenic?

galanin

orexigenic

11

Orexigenic or anorexigenic?

insulin

orexigenic

12

Orexigenic or anorexigenic?

Leptin

anorexigenic

13

Orexigenic or anorexigenic?

GLP-1

Anorexigenic

14

Orexigenic or anorexigenic?

Amylin

anorexigenic

15

Orexigenic or anorexigenic?

CCK

Anorexigenic

16

Orexigenic or anorexigenic?

Thyroid hormone

Anorexigenic

17

Orexigenic or anorexigenic?

PPAR

orexigenic

18

Which carried a greater risk of diabetes/ HTN, heart disease....visceral or lower body fat?

visceral

19

Name some genetic risk factors of obesity?

Mutations in leptin, leptin receptor, POMC

20

"extreme obesity, rregular breathing, cyanosis, secondary polycythemia, RV dysfunction, persistent pulmonary HTN"

Pickwickian Syndrome

21

Fat cells in obesity undergo...

Hyperplasia and hypertrophy