Bone: Tumors of Bone Flashcards Preview

Pathology Unit 5 > Bone: Tumors of Bone > Flashcards

Flashcards in Bone: Tumors of Bone Deck (21):
1

Name the tumor:

benign tumor, metaphysis of long bone, whored oattern of spindle cells

Nonossifying fibroma

2

Name the tumor:

children/adolescent, benign, fluid filled and unilocular lesion, males

solitary bone cyst

3

Name the tumor:

children/ young adults, pain/ swelling and rapid growth with possible "blow out" rupture and hemorrhage

Aneurysmal bone cyst

4

Name the tumor:

benign tumor of compact cortical bone, if multiple associated with gardner syndrome

osteoma

5

Name the tumor:

benign, painful lesion pf osseous tissue (the nidus) and surrounded by a halo of reactive bone formation, diaphysis of tubular leg bones, painful at NIGHT and with ALCOHOL

pain relieved by aspirin

Osteoid osteoma

6

Name the tumor:

uncommon, benign, large, resembles osteoid osteoma, NO NOCTURNAL PAIN, spine and long bones

osteoblastoma

7

Name the tumor:

benign intrapsseous tumor of mature hyaline cartilage, METACARPLES and PHALANGES of the hands

Solitary chondroma (enchondroma)

8

Name the tumor:

benign, epiphysis of long bones, males, sheets of primitive chondroblasts and primitive matrix, bone destruction with pain

Chondroblastoma

9

Most common primary malignant bone tumor?

osteosarcoma

10

Name the tumor:

boys, age 10-20, Rb and p53 mutations, enlarging lytic and blastic mass of disorganized bone tissue

Osteosarcoma

11

Where does osteosarcoma usually metastasize to?

lungs

12

What is osteosarcoma (+) for?

AP (+) and osteonectin (+)

13

Name the tumor:

cartilagnous malignancy?

chondrosarcoma

14

What are the common varients of chondrosarcoma?

1- central chondrosarcoma (most common)

2- periheral condrosarcoma

3- juxtacortical chondrosarcoma

15

Name the tumor:

benign locally aggressive neoplasm characterized by the presence of osteoclastic, multinucleated giant cell

giant cell tumor

16

T/F: giant cell tumor commonly recurrs after resection

true

17

Name the tumor:

primitive neuroectodermal tumor of childhood, boys, Homer-Write rosettes, lytic lesions, "onion skin" periosteal reaction

Ewing Sarcoma

18

Name the tumor:

plasma cell tumor, lytic bone lesions, cytokine release that recruitss osteclasts, amyloid deposits

Multiple myeloma

19

Which carcinomas are known to met to bone?

Breast, prostate, lung, thyroid, kidney, wilms tumor

20

Which mets produce dense foci?

prostate
breast
lung
stomach

21

Which mets produce lytic lesions?

thyroid
GI
Kidney
Neuroblastoma