Brain Neoplasms I Flashcards Preview

MBB Block II > Brain Neoplasms I > Flashcards

Flashcards in Brain Neoplasms I Deck (10):

What are the differences between the locations of neoplasms in adults vs. kids?

supratentorial in adults
infratentorial in kids


What are the common brain tumors of children?

astrocytomas (pilocytic), medulloblastomas, and ependymomas


What are the common brain tumors of adults?

astrocytomas, glioblastomas, oligodendroglioma, ependymomas, nerve sheath tumors, and metastases


Childhood astrocytomas; age, sites, prognosis

first decade; CEREBELLUM or hypothalamus, best survival rates


Histologic features of childhood astrocytomas

pilocytic- unlike many astrocytomas, there are clearer boarders.
you will see cystic regions and more dense regions
fibrillary processes
ROSENTHAL FIBERS (hyper-pink sausage shapes in a fibrillary backround)


What are sites, age, and prognosis of medulloblastomas?

site: cerebellar vermis
age: first decade and early 20s
prognosis: around 80% cure; lower in high risk groups


Histologic features of medulloblastoma

immature looking cells (very purple)
HOMER-WRIGHT ROSETTES: white in the middle


Childhood ependymoma: site, age, prognosis

site: 4th ventricle (though possilbe in any ventricle)
age: 1st decade
prognosis: 86%- midway btw pilocytoma and medulloblastoma


Histologic features of childhood ependymomas

also look kind of fibrillary, though more anaplastic tumors may show high cell density, pelomorphism and mitotic activity
PERIVASCULAR PSEUDOROSETTES (surround blood vessels. immediately around the vessels is pink stuff, not cells)


What is the least common type of childhood tumor? Presentation? Location? Prognosis?

choroid plexus papilloma/carcinoma
usually presents in the lateral ventricles (4th ventricle in adutls) with hydrocephalus
prognosis excellent for choroid plexus papillomas
prognosis "guarded" for choroid carcinomas