Flashcards in Brain Neoplasms I Deck (10):
What are the differences between the locations of neoplasms in adults vs. kids?
supratentorial in adults
infratentorial in kids
What are the common brain tumors of children?
astrocytomas (pilocytic), medulloblastomas, and ependymomas
What are the common brain tumors of adults?
astrocytomas, glioblastomas, oligodendroglioma, ependymomas, nerve sheath tumors, and metastases
Childhood astrocytomas; age, sites, prognosis
first decade; CEREBELLUM or hypothalamus, best survival rates
Histologic features of childhood astrocytomas
pilocytic- unlike many astrocytomas, there are clearer boarders.
you will see cystic regions and more dense regions
ROSENTHAL FIBERS (hyper-pink sausage shapes in a fibrillary backround)
What are sites, age, and prognosis of medulloblastomas?
site: cerebellar vermis
age: first decade and early 20s
prognosis: around 80% cure; lower in high risk groups
Histologic features of medulloblastoma
immature looking cells (very purple)
HOMER-WRIGHT ROSETTES: white in the middle
Childhood ependymoma: site, age, prognosis
site: 4th ventricle (though possilbe in any ventricle)
age: 1st decade
prognosis: 86%- midway btw pilocytoma and medulloblastoma
Histologic features of childhood ependymomas
also look kind of fibrillary, though more anaplastic tumors may show high cell density, pelomorphism and mitotic activity
PERIVASCULAR PSEUDOROSETTES (surround blood vessels. immediately around the vessels is pink stuff, not cells)