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Flashcards in Brain Tumours Deck (28)
1

What is a glioma?

A malignant tumour of epithelial origin

2

What type of brain tumour is associated with neurofibromatosis?

Glioma

3

Which is the only way by which gliomas tend to spread?

Direct extension - they virtually never spread to beyond the CNS

4

Name two types of gliomas

Astrocytoma
Oligodendroglioma

5

What stage is a glioblastoma multiforme?

4

6

Are grade 1 astrocytomas benign or malignant?

Benign

7

What is the treatment for a grade 1 astrocytoma?

Surgery - curative

8

Who most often gets pliocytic astrocytomas? Where do they most often occur?

Children
Cerebellum

9

What four locations do pilocytic astrocytomas occur?

Optic nerve
Hypothalamus
Cerebellum
Brainstem

10

How do low grade astrocytomas most commonly present?

Seizures

11

What is the treatment for grade 2 astrocytomas?

Surgery +/- radio/chemo therapy depending on the molecular profile

12

What is another name for a grade 2 astrocytoma?

Glioblastoma

13

What is the normal survival time for a glioblastoma multiforme?

Less than 1 year

14

What is the normal survival time for an anaplastic astrocytoma?

2 years

15

In what lobes do oligodendoglial tumours most commonly occur?

Frontal

16

How do oligodendroglial tumours present usually?

Seizure

17

Which type of brain tumour tends to have peripheral calcification?

Oligodendroglial tumour

18

What is the treatment for oligodendroglial tumours?

Chemotherapy (Procarbazine, lomustine, vincristine) and surgery
Radiotherapy helps in decreasing seizures.

19

What is the median survival for an oligodendoglial tumour?

10 years

20

What is the treatment for grade III and IV astrocytomas?

Non curative surgery (increases survival quality)
External beam radiation
Chemo ( Temozolomide, PCV, Carmustine wafers)

21

What are the common presenting symptoms of meningiomas?

Headaches
Cranial nerve neuropathies (if on base of skull)
Regional anatomical disturbance

22

Are meningiomas most commonly benign or malignant?

Benign

23

What are the four types of aggressive/malignant meningiomas?

Clear cell
Chordoid
Rhabdoid
Papillary

24

A 56 year old women has a CT scan after suffering debilitating and constant headaches. On the CT you see a densely enhanced homogenous lesion with oedema around it and hyperostosis.

Meningioma

25

What is hyperostosis?

Excssive growth of bone

26

Where is the most common place for neurofibromas to occur?

Cerebellopontine angle

27

A patient is confirmed to have bilateral acoustic neuromas. What underlying condition might he have?

Neurofibromatosis type 2

28

What is an acoustic neuroma?

A neurofibroma of the VIIIth nerve sheath