Flashcards in Neurology Week 2 Basic Questions Deck (14)
Which are the most numerous cells in the nervous system?
Opening of which channel causes the upstroke of the action potential? Which way is the flow?
Sodium flows inwards causing depolarization
Opening of which channel causes the downstroke of the action potential? Which way is the flow?
Pottassium flows outwards causing hyperpolarization
Are depolarizing responses excitatory or inhibitory?
Are hyperpolarizing responses excitatory or inhibitory?
What kind of substances are glutamate, GABA and Glycine?
What kind of substances are Acteylcholine, Dopamine, Histamine, Noradrenaline and Serotonin?
Which mediates fast transmisson; Ionotropic ligand gated ion channels or G protein coupled receptors?
Ionotropic ligand gated ion channels
What channel does the GABAa receptor operate?
Chlorine (Then a pottassium channel)
How do Benzodiazepines work?
Positive modulator of GABAa so enhance calcium entry and enhance inhibition
How does Baclofen work?
Agonist of the GABAb receptor and enhances the pottassium current, increasing inhibition
What is meant by an excitatory neurone?
A neurone that releases a depolarizing neurotransmitter
What is meant by an inhibitory neurone?
A neurone that releases a hyperpolarizing neurotransmitter