Breast

Question 1

What is a risk assessment tool that calculates invasive CA risk in the next 5 years and overall risk? Focussed on first degree relatives

Answer 1

Gail model

Question 2

What risk assessment tool incorporates 1st and 2nd degree male and female relatives and family members w/ ovarian CA. No personal/ lifestyle risks.

Answer 2

Claus model

Question 3

What is a model that is given for high risk women in a given family? It maps out mutation frequencies, penetration/ affected carriers. Age of onset: 1st and 2nd degree male and female relatives

Answer 3

RBCAPRO model

Question 4

What is the primary node that drains the area from around the breast? This is usually tested during a mastectomy.

Answer 4

Sentinel node

Question 5

When is the ideal time for the BSE to be performed?

Answer 5

5-7 days after onset on menses

Question 6

When is nipple discharge considered abnormal?

Answer 6

If occurs >6 months after cessation of breast feeding

Question 7

How often should a CBE be done for women 20-39?

Answer 7

Every 1-3 years

Question 8

How often should CBE be done for women over 40?

Answer 8

Annually

Question 9

When should mammograms be done according to ACOG, AMA, and ACS?

Answer 9

Annually >40 years old

Question 10

When does USPSTF believe mammography should be given?

Answer 10

every 2 years from 50-74 y/o

Question 11

ER positive cancer means what?

Answer 11

Estrogen receptor positive

Question 12

According to ACS when should a women get a MRI?

Answer 12

Known lifetime risk >20%
BRCA mutation (or 1st degree relative with)
Chest radiation (ages 10-20)
patient with 1st degree relative has high risk genetic cancer
Known risk 15-20%
Breast CA, LCIS< DCIS atypical hyperplasia
Dense/ uneven breasts

Question 13

A women who had ER positive cancer can use this drug for chemoprevention in post cancer.

Answer 13

SERMs

Question 14

What are two types of SERMs?

Answer 14

Thamoxifen

Raloxifene

Question 15

What are some side effects of SERMs?

Answer 15

Endometrial Ca
thromboembolic events
Cataracts

Question 16

What SERM is for post-menopausal women and has less side effects?

Answer 16

Raloxifene

Question 17

What’s the first question to ask?

Answer 17

Do you have any breast concerns/ issues today?

Question 18

Green nipple discharge can indicate what?

Answer 18

Fibrocystic changes

Question 19

Are breast cancers usually tender or non-tender?

Answer 19

Non-tender

Question 20

What shape is not reassuring in a breast exam?

Answer 20

Irregular

Question 21

Is it better for a mass to move or fixed?

Answer 21

Move

Question 22

What consistency indicates a non-cancerous mass?

Answer 22

Smooth, rubbery,

Question 23

What is usually found in pre menopausal women, well defined, round, mobile. No skin retraction. Non-proliferative

Answer 23

Cyst

Question 24

What is a discrete, round, firm, mobile & nontender, solitary. No skin retraction, reproductive years usually.

Answer 24

Fibroadenoma

Question 25

What are 3 types of proliferative lesions without atypia?

Answer 25

* intraductal papillomas * epithelial hyperplasia * sclerosing adenosis

Question 26

What are the 2 types of proliferative lesions with atypia?

Answer 26

LCIS | DCIS

Question 27

This type mass is very mobile, well delineated, may be soft or firm, is round, disclike or lobular and is usually found in young adults.

Answer 27

Fibroadenoma

Question 28

This type of breast mass are round and soft to firm, usually elastic. They are well delineated and mobile and often tender. Usually found in women 30-50.

Answer 28

Breast cyst

Question 29

This breast is most commonly found in women over 50. Has an irregular or stellate shape and is firm or hard. Not clearly delineated and may be fixed to skin or underlying tissues. Retraction may be present.

Answer 29

Cancer

Question 30

Which type breast cyst is often tender?

Answer 30

Cyst

Question 31

What does edema of the skin of the brast indicate?What is a name for this

Answer 31

Produced by a lymphatic blockade | Called peau d'orange sign

Question 32

What type of brast cancer starts as a scaly eczemalike lesion that may weep, crust, or erode. Breast mass may be present. Suspect this with any persisting dermatitis of the nipple and areola.

Answer 32

Paget's Disease of the Nipple

Question 33

What does spontaneous unilateral bloody discharge from one or two ducts of the nipple suggest?

Answer 33

Intraductal papilloma Ductal carcinoma in situ Paget's disease of the breast

Question 34

What is nonpuerperal galactorrhea?

Answer 34

Milky discharge unrelated to a prior pregnancy.

Question 35

What are SERMs?

Answer 35

Selective estrogen receptor modulators

Question 36

What are 2 SERMs?

Answer 36

Tamoxifen and raloxifene

Question 37

Who is raloxifene approved for?

Answer 37

Post menopausal women

Question 38

When is the best time to do a clinical breast exam?

Answer 38

5 to 7 days after the onset of menses

Question 39

This arises from an imbalance of estrogens and androgens in males sometimes drug related.

Answer 39

Gynecomastia

Question 40

What is the name for a sweat gland infection?

Answer 40

Hidradenitis syuppurativa