CAL - Respiratory Pathology Quiz Flashcards Preview

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Flashcards in CAL - Respiratory Pathology Quiz Deck (14):

Where are ciliated epithelial cells?

respiratory bronchioles - not interspersed with goblet cells as with the conducting parts of the respiratory system


What is the most susceptible part of respiratory mucosa to infection?

bronchiole-alveolar junction


What cells are important in pathogenesis of primary atelectasis?

type 2 epithelial cell/ type 2 pneumocyte. also respond rapidly to type 1 cell damage by proliferating


What happens to alveolar macrophages after ingesting matter?

pass into airways, trapped in mucus, carried to larynx, coughed up or swallowed. Some enter lymphatics


What is a clara cell?

club shaped cell = bronchiolar exocrine cells
- non-ciliated, dome shaped, line terminal bronchioles, most numerous in distal bronchiole, produce component of surfactant, contain detoxifying enzymes, can acts as stem cells so can replace damaged cells.


What might cause downgrowth of epidermial hyperplasia towards dermis??

- inflammatory polyp
- allergic rhinitis
- haematoma
- mycotic rhinitis


Histology - severe RAO/ chronic bronchiolitis emphysema

- plasma cell aggregation, lymphocytes and eosinophils around bronchioles
- smooth mm hypertrophy
- mucus accumulation --> obstruction --> alveolar emphysea


Define histiocytosis

abnormal number of immune cells called histiocytes


Which mm hypertrophy to cause heaves lines?

lateral and external abdominal olique muscles


Describe a lung in a chronic stage of infection

- pale
- very nodular
- emphysema
- atelectasis
- pockets of inflammatory cells and exudate
- bronchiectasis (partial rupture of bronchiolar walls)
- interstitial fibrosis
- pallor and nodularity
- firm and will not collapse


Describe a lung in the sub-acute phase of infection

- dark red (leaked blood and fibrin)
- slightly undulating surface
- emphsema
- atelectasis


Describe a lung in acute phase of infection

- dark red (active hyperaemia)
- shiny and moist surface (oedema into interstitium and alveoli)
- smooth surface (no suppurative material accumulation)
- no fibrosis


T/F - emphysema is always a secondary lesion in animals

True - unlike man. Can occur in animals with bronchopneumonia due to air OT obstruction


What is Suxavyn?

a vaccine against PCV-2. only partially protective because 12 serotypes are known and this vaccine only protects against serotypes 3,6 and 8. Also this organism has other virulence factors not included in this vaccine (e.g. fimbrial adhesion factors, OMPs, Fe-binding proteins, MMPs, urease, others)