Carbapenams Flashcards
(6 cards)
What type of spectrum do carbapenems have?
Broad-spectrum
Carbapenems are effective against a wide range of bacteria.
Are carbapenems active against MRSA?
No
Carbapenems do not work against Methicillin-resistant Staphylococcus aureus.
How do carbapenems compare to penicillins?
They are similar
Both carbapenems and penicillins belong to the beta-lactam class of antibiotics.
What is the role of cilastatin when administering imipenem?
To prevent inactivation
Imipenem is inactivated in the kidney, thus cilastatin is co-administered.
Are the rest of the carbapenems inactivated by enzymatic activity in the kidney?
No
Other carbapenems do not undergo inactivation like imipenem.
List some side effects of carbapenems.
- Diarrhea
- Headache
- Nausea
- Vomiting
These are common adverse effects experienced by patients taking carbapenems.
