Cephalosporins Flashcards
(10 cards)
What are Cephalosporins?
Broad-spectrum antibiotics
How do Cephalosporins affect bacteria?
They attach to penicillin binding proteins to interrupt cell wall biosynthesis, leading to bacterial cell lysis or death
To which class of antibiotics are Cephalosporins similar?
Penicillins
How are Cephalosporins excreted from the body?
Renally
Which Cephalosporins are suitable for infections of the CNS?
Cefotaxime and ceftriaxone
List some examples of Cephalosporins.
- Cefalexin
- Cefradine
- Cefadroxyl
- Cefotaxime
- Cefixime
- Cefdazimide
- Ceftriaxone
What indicates a third generation Cephalosporin?
Anything with the letter T inside it
In which generations of Cephalosporins is antibiotic-associated colitis more common?
Third and second generation
What is the main side effect of Cephalosporins?
Hypersensitivity
Can Cefalexin be given in patients with penicillin allergy?
No
