Tetracyclines Flashcards
(15 cards)
What do all tetracyclines end with?
Cycline
What is tetracycline used for in relation to MRSA?
Specifically vancomycin
Which tetracycline is an exception due to its differences?
Minocycline
What is a significant risk associated with minocycline?
Greater risk of lupus-like syndrome
What irreversible effect can minocycline cause?
Irreversible pigmentation
What general caution should be noted with tetracyclines?
Can increase muscle weakness in patients with myasthenia gravis
Which substances decrease the absorption of tetracyclines?
- Antacids
- Aluminium
- Calcium
- Iron
- Magnesium
- Zinc salts
What food can also reduce the absorption of tetracyclines?
Milk
How should tetracyclines be taken in relation to indigestion tablets or iron-zinc tablets?
More than two hours before or after medication
What is the dosing recommendation for tetracyclines?
Doses should be spaced evenly through the day
What precaution should be taken regarding sunlight when using tetracyclines?
Protect the skin from sunlight
What side effects are associated with tetracyclines? List at least three.
- Nausea
- Vomiting
- Diarrhea
- Intracranial hypertension
- Photosensitivity reactions
- Skin reactions
- Discoloration of teeth
- Dysphagia
Who should not take tetracyclines?
- Under-12s
- Pregnant women
- Breastfeeding women
What do tetracyclines bind to in the body?
Growing teeth and bones
In what condition should tetracyclines be avoided or used with caution?
Hepatic impairment