cardiac Flashcards

(61 cards)

1
Q

what is the equation for flow

A

chnage in pressure/ R (resistance)

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2
Q

_____ opposes flow

A

resistance

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3
Q

flow follows pressure gradient which means it goes from where to where

A

left ventricle –> right atrium
right ventricle —> left atrium

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4
Q

hydrostatic pressure decreases due to

A

friction

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5
Q

forward or driving pressure is strong in ______ contraction

A

ventricular

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6
Q

flow is proportional to change in _____

A

pressure

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7
Q

what factors affect resistance

A

vasoconstriction or dilation; blood viscosity (directly proportional) ; vessel length (directly proportional; longer vessel, more resistance)

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8
Q

pressure generated by ventricular contraction

A

mean arterial pressure

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9
Q

CO =

A

cardiac ouput; volume per time

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10
Q

____ maintain pressure during ventricular relaxation

A

arteries

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11
Q

MAP = ____ X ___

A

CO X R

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12
Q

what system innervates entire heart (using NE and E)

A

sympathetic

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13
Q

parasympathetic innervates _____ (primarily the atria)

A

cranial nerve (uses ACH)

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14
Q

pacemakers nodal tissues and conduction fibers; generate and conduct action potentials

A

autorhythmic cells

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15
Q

what two channels are responsible for excitation contraction coupling in T-tubules

A

voltage gated Na+ channels and L type Ca2+ channels

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16
Q

the sarcoplasmic reticulum of the cardiac muscle has

A

ryanodine receptors and Ca2+ release

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17
Q

the sarcolemma has two ATPase pumps for relaxation; what are they

A

Na/ K (3 Na out; 2 K in)
Ca/ ATPase
also a Na+ and Ca2+ exchanger (NCX)

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18
Q

what two factors impact cardiac contractility

A

force developed is proportional to # of active crossbridges
sarcomere length of onset of contraction

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19
Q

the length-tension relationship ( increased length; increased force)

A

frank-starling law of the heart

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20
Q

rapid depolarization of the ventricular myofibers is due to

A

voltage gated Na channels open

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21
Q

the plateau phase has what voltage gated channels

A

L -type Ca 2+ channels (K+ are closed) slow K+ are open

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22
Q

the ___ period in a cardiac muscle fiber lasts almost as long as the entire muscle twitch

A

refractory

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23
Q

unstable resting membrane potential uses what channels? Which channel has greater movement

A

Na+ and K+ channels; Na+ movement is larger

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24
Q

sodium channels being inactive causes

A

absolute refractory period

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25
Repolarization is quickly interrupted as voltage-gated L-type calcium channels open, increasing calcium permeability and bringing positively charged calcium ions into the cell. Why is this unique?
Calcium has a large role in initiating AP
26
Phase 4: The trace begins with a slow, incremental depolarization. Phase 0: Incremental depolarization is followed by a rapid depolarization when the threshold is reached. Phase 3: There is a rapid repolarization and then the incremental depolarization (Phase 4) begins again and the cycle repeats.
phases of pacemaker AP
27
____ = pacemaker; 90-100 bpm (internodal pathway); communicate with atrial contractile cells
SA node
28
does 25-40 bpm; transmit signals across fibrous skeleton
AV node
29
contractile cells in the apex of the heart; help with direction of contraction
small purkinje fibers
30
make up the atrioventricular bundle and right and left bundle branches
purkinje fibers
31
right arm to left arm
lead I
32
right arm to left leg
lead II
33
left arm to left leg
lead III
34
which lead most closely follows electrical axis of the heart
35
current of ECG moves from
negative to positive
36
atrial depolarization
P wave
37
ventricular depolarization & atrial repolarization
QRS complex
38
ventricular repolarization
T wave
39
____ events precede ___ events
electrical; mechanical
40
systole = ____ and ____
contraction and emptying
41
valves from atrium to ventricle
atrioventricular
42
when atrial pressure is greater the ventricular pressure the AV valves ___
open (ventricles relax)
43
ventricles to great artery
semilunar valves
44
as the ventricles contract the pressure in the ventricles exceeds pressure in the arteries; what valves are open?
semilunar
45
the final filling (20%) of the ventricles gives what sound
S4
46
during atrial depolarization and systole, the atria are _____ and _____
contracting and emptyinh
47
during ventricular depolarization and systole, the ventricles are in
isovolumetric contraction
48
the first heart sound S1 happens when AV valves are
closed
49
during early ventricular diastole the ventricles are in
isovolumetric relaxation
50
the second S2 sound happens when SL valves are
closed
51
passive filling of ventricles is represented by what heart sound
S3
52
volume of blood ejected by the ventricular system
stroke volume
53
volume of blood at the end of ventricular diastole
end diastolic volume
54
SV = ?
EDV-ESV
55
CO (cardiac output) =
HR x SV
56
the ____ is in charge of tonic control of the SA rate and HR
parasympathetic
57
three factors for regulation of stroke volume
length, sympathetic input to ventricles , afterload
58
ejection fraction (EF) = SV/EDV
59
the ____ is what you have to work against in aorta
afterload
60
rapid but regular SA rate and atrial contraction but relatively normal ventricular contractions
atrial flutter
61