Cardiomyopathies (Hypertrophic Cardiomyopathy)

Question 1

What is hypertrophic cardiomyopathy?

Answer 1

Left ventricular hypertrophy without underlying hypertension or valvular disease

Hypertrophic cardiomyopathy is characterized by thickened heart muscle, particularly affecting the left ventricle.

Question 2

What is the systolic function in hypertrophic cardiomyopathy?

Answer 2

Usually normal

Despite the thickening of the heart muscle, the heart can still pump effectively during systole.

Question 3

What happens to diastolic filling pressure in hypertrophic cardiomyopathy?

Answer 3

Increased due to increased left ventricular stiffness

This increased stiffness affects the heart’s ability to relax and fill properly during diastole.

Question 4

What is the prevalence ranking of hypertrophic cardiomyopathy among cardiomyopathies?

Answer 4

Second most common cardiomyopathy

Hypertrophic cardiomyopathy follows dilated cardiomyopathy in terms of prevalence.

Question 5

What are the causes of hypertrophic cardiomyopathy?

Answer 5

Sarcomere protein mutations

These mutations affect the proteins that make up the heart muscle, leading to hypertrophy.