CC REVA Flashcards by Chum SJM

Uric acid conversional to SI

a.Use 0.0595
b.0.0025
c.12.9
d.0.0113

0.0595

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Used to calibrate the centrifuge?

a.strobe light
b.tachometer
c.timer
d. AOTA

D. AOTA

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EDTA is known for carry over; it should be filled first among all ther tubes

a.both correct
b.both incorrect
c.1st statement is correct
d.2nd statement is correct

1st statement is correct

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Fist clenching will cause false elevation of this electrolyte?

a.potassium
b.calcium
c.sodium
d.chloride

Potassium

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A bright red blood pulsates during venipuncture, what is the first thing to do?

a.call the supervisor
b.apply pressure on the site
c.stop the extraction
d.ignore and continue the extraction

Stop the extraction

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For HbA1C detection and hemoglobinopathy?

a.HPLC
b.AAS
c.tubidimetry
d.spectrophotometry

HPLC

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It minimizes unwanted stay light and prevents the entrance of scattered light into the monochromator

a.entrance slit
b.photodetector
c.exit slit
d.light source

Entrance slit

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It measures the amount of light intensity present over a zero background, and is affected by quenching though 1000x more sensitive than spectrophotometer?

a.chemiluminescence
b.fluoremetry
c.osmometry
d.electrochemistry

Fluorometry

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Is the measure of the current flow produced by an oxidation reaction?

a.polarography
b.amperometry
c.voltammetry
d.coulometry

Amperometry

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Migration of particles in an electric field?

a.electrophoresis
b.countercurrentphoresis
c.PCR
d.DNA amplification

Electrophoresis

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The ff. are factors that affect the rate of migration of molecules?

1.net electric charge of the molecule
2.size and shape of the molecule
3.electric field strength
4.nature of the dye
5.temperature

a.AOTA
b.12345
c.1345
d.1235

1345

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For quantitating separated proteins in electrophoresis?

a.nephelometry
b.spectrophotometry
c.FEP
d.densitometry

Densitometry

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Used to check wavelength accuracy?
1.didymium
2.holmium oxide filter
3.dichromate solution

a.1
b.1,2
c.1,2,3
d.2

1, 2

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Which is the most commonly used light source in the lab?

a.deuterium lamp
b.tungsten light bulb
c.continuum source
d.B and C

Tungsten light bulb

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This test is useful in testing galactosemia, MSUD, and congenital hypothyroidism- these metabolic disorders of newborn?

a.GC-MS
b.tandem mass spectrometry
c.HPLC
d.reverse HPLC

Tandem mass spectrometry

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It can detect structural information and determination of molecular weight?

a.GSC
b.HPLC
c.MS
d.partition chromatography

Mass Spectrometry (MS)

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Potentiometry measures voltage changes due to free ions. Which are true?
1.for measuring pH and pO2
2.calomel and silver-silver chloride for measuring pH
3.for measure pH and pCO2

a.1,3
b.1,2
c.1,2,3
d.2,3

2, 3

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What kind of quality control is important in maintaining long term accuracy of the analytical methods?

a.internal quality control
b.external quality control
c.sensitivity
d.specificity

External quality control

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For long term accuracy of laboratory results

a.external qc
b.internal qc
c.intralab qc
d.NOTA

External QC

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What is the acceptable range or confidence limit in quality control?

a.99%, +/- 2SD
b.68%, +/- 2SD
c.93%, +/- 2SD
d.95%, +/- 2SD

95%, +/-2SD

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If 2SD is 5.6, what is the 1SD?

a.2.8
b.5.6
c.16.8
d.cannot be determined

2.8

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The ff. are systematic errors, except?
1.pipetting error
2.temperature fluctuation
3.improper calibration of the machine
4.contaminated reagent

a.1
b.1,2
c.1,2,3
d.1,2,3,4

1, 2

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A measure of dispersion of values from the average?

a.mean
b.median
c.standard deviation
d.coefficient of variation

Standard Deviation

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It is a system where it house samples and reagents into a separate container, wherein multiple tests can be run on a single sample or vice versa?

a.centrifugal analyzer
b.discrete analyzer
c.continuous flow analyzer
d.fibrometer

Discrete analyzer

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The rider delayed the release of send out test result, what type of error is indicated? a.pre analytical b.analytical c.post analytical d.NOTA

Post-analytical

On a QC chart, a corrective action must be considered when: a.6 consecutive control values are drifting withing +/- 2s b.6 consecutive control values are above the mean but within +/- 2s c.presence of one outlier d.one control values outside the area of +/- 3s

One control value outside ±3SD

The glycated hemoglobin value represents the blood glucose value during the preceding a.1 to 3 weeks b.2 to 3 weeks c.3 to 6 weeks d.8 to 12 weeks

8–12 weeks

Normal CSF glucose with lymphocytosis and normal lactate is indicative of? a.viral meningitis b.amebic encephalitis c.bacterial meningitis d.AOTA

Viral meningitis

Formation of glucose 6 phosphate from noncarbohydrate sources. glycerol from lipids (fats, adipose), pyruvate and lactate from amino acids? a.glycolysis b.glycogenolysis c.glycogenesis d.gluconeogenesis

Gluconeogenesis

Specimen with much older RBC from a patient with iron deficiency anemia would create what HbA1c result? a.low b.normal c.high d.false low

High

Patient with hemoglobin C is advised to undergo what test to measure glucose? a.HbA1c b.fructosamine c.glycated albumin d.B and C

B and C (Fructosamine and Glycated albumin)

what is the most specific method as well as the reference method for glucose testing? a.glucose oxidase b.polarographic glucose oxidase c.hexokinase d.HbA1c

Hexokinase

what is the screening test for diagnosis of gestational DM? a.GCT using 75g b.GCT using 50g c. OGTT using 75g d. OGTT using 50g

GCT using 50g

Preferred tube for glucose analysis? 1.gray top 2.light blue 3.sodium fluoride 4.calcium fluoride

1, 3 (gray top, sodium fluoride)

The presence of vitamin C to benedict’s method will produce what result? a.false positive b.false negative c.nothing, it won’t affect d.neutral

False positive

test result shows: 1.high glucose 2.decreased C peptide level 3.autoantibody (+) 4.serum ketones: elevated a.juvenile onset DM b.ketosis resistant DM c.geneticist nightmare d.stable DM

Juvenile onset DM

Standing specimen for glucose assay was left standing for 2 hours on the table, the glucose level would be expected to decrease how many per hour? a.2% b.2mg/dl c.7% d.7mg/dL

7 mg/dL

HDL cholesterol level protective against heart disease a.>60 mg/dL b.<40 mg/dL c.40-50 mg/dL d.<100 mg/dL

>60 mg/dL

39.fasting requirements of TAG measurement? a.8-14 hrs b.10-14 hrs c.12-14 hrs d.14 hrs

12–14 hours

what is the reference method for quantitation of lipoproteins? a.electrophoresis b.ultracentrifugation c.abell kendal d.van handel

Ultracentrifugation

what is the CDC reference method for TAG measurement? a.modified van handel and zilversmith b.chromatographic method c.ultracentrifugation d.fluorescent polarization

Modified van Handel and Zilversmith

Acute pancreatitis is seen in triglyceride level of? a.<150 mg/dL b.199 mg/dL c.240 mg/dL d.500 mg/dL

500 mg/dL

the ff. are true about lipoprotein except: a.HDL is the smallest lipoprotein that transport cholesterol from tissue to the liver b.chylomicron transports exogenous or dietary cholesterol to liver c.VLDL transports endogenous triglyceride from the liver to the tissues d.LDL transports cholesterol to the peripheral

chylomicron transports exogenous or dietary cholesterol to liver

Is an abnormal lipoprotein found in obstructive jaundice and LCAT deficiency, a specific and sensitive indicator of cholestasis? a.Lpx b.Lpa c.B-CLDL d.IDL

LpX

Transport protein of iron: a.ferritin b.hemoglobin c.ceruloplasmin d.transferrin

Transferrin

First protein to peak during acute myocardial infarction, a useful marker for monitoring the success or failure of reperfusion? a.troponin I b.troponin T c.myologbin d.CK-MB

`Myoglobin

is the removal of the substamce from plasma into urine over a fixed time? a.concentration b.clearance c.GFR d.nephron

Clearance

what is the ratio of BUN to creatinine? a.1:10 b.10:1 - 20:1 c.1:10 - 1:20 d.20:1

10:1 - 20:1

A deficiency of hypoxanthine-guanine phosphoribosyl transferase (HGPRT), also known as orange sand diaper syndrome? a.chronic renal disease b.gout c.lesch-nyhan syndrome d.uremia

Lesch-Nyhan syndrome

Jaffe reaction is used to determine what non protein nitrogen? a.creatinine b.uric acid c. urea d. protein

Creatinine

most useful indices to measure liver damage severity? a. albumin and globulin b. albumin and vit. k dependent coagulation factors c.kjeldahl and biuret d.ultraviolet

Albumin and Vitamin K-dependent coagulation factors

Which among the following is not part of beta globulin? a.transferrin b.complement system c.lipoprotein d.ceruloplasmin

Ceruloplasmin

Spike at late alpha 2 and early beta region in serum electrophoresis is associated to: a.transferrin - IDA b.AMG - nephrotic syndrome c.haptoglobin - recent hemolysis d.ceruloplasmin - wilson’s disease

AMG - Nephrotic syndrome

True about protein salt fractionation: 1.sodium chloride is used as a precipitating agent 2.globulin will be in supernatant while albumin precipitates a.both are correct b.both are incorrect c.only the first statement is correct d.only the second statement is correct

Both are incorrect

what is the normal ratio of globulin to albumin? a.1:3 - 3:1 b.1:1 - 3:3 c.1:3 d.20:1

1:1 - 3:3

long prothrombin time after the administration of vit K in vitamin k response test: a.expired vit. k reagent leading to false prolong PT b.bile duct obstruction - conjugation problem c.chronic hepatitis - synthetic problem d.reye’s syndrome - detoxification problem

Chronic hepatitis - synthetic problem

Jaundice can be seen in bilirubin level exceeding: a.1 mg/dL b.5 mg/dL c.3 mg/dL d.9 mg/dL

3 mg/dL

Diazo test using evelyn and malloy shows: w/o methanol: 9 mg/dL w/methanol: 14 mg/dL what are the total bilirubin, b1, and b2? a.23,14, 9 b.14, 9, 5 c.23, 14, 5 d.14, 5, 9

14, 9, 5

True about bilirubin measurement? 1.B1 reacts slowly with diazo reagent 2.B2 does not need accelerant to be measured 3.visible icterisia can be seen if bilirubin exceeds 25 mg/dL 4.bilirubinometer is not recommended to adult due to carotene a.AOTA b.1, 2, 4 c.NOTA d.3, 4

AOTA (All of the above)

what type of bilirubin is seen in kernicterus? a.delta bilirubin b.B2 c.B1 d.any of the above

B2 (unconjugated)

preanalytic requirement/s for the test to determine liver detoxification function? 1.venipuncture must not be longer than 1 minute 2.smoking will cause false decrease result 3.must be placed in ice immediately 4.heparin should not be used for it will interfere crystal identification a.AOTA b.3,4 c.1,2,3 d.3 only

3 only

The following are transferases except: a.CK b.AST c.ALT d.LPS

Lipase (LPS)

A short statured patient who complained about bone fracture will show what bowers and mccomb result? a.high parathyroid hormone b.increase ALP then normalize after the addition of 3M urea and phenylalanine c.Increase ALP then normalize after the addition of levamisole d.Increase ALP and consistent high after the addition of 3M urea

Increase ALP then normalize after the addition of levamisole

The doctor requested for ACP from a patient suspected of cancer. Test shows: consistently increased ACP even after the addition of L-tartrate. This shows? a.prostatic carcinoma b.hemolyzed sample c.AMI d.NOTA

Hemolyzed sample

Which among the following enzyme will increase in wolff-parkinson white syndrome? a.AST b.ALT c.both A and B d.NOTA - it’s ACE

AST

What will increase in Reye's syndrome? 1.SGOT 2.SGPT 3.AMMONIA a.AOTA b.2 c.2, 3 d.1, 2

All of them

De ritis ratio is seen in: a.cirrhosis b.ALT:AST is <1.0 c.AST:ALT is >1.0 d.recent hepatitis

C. AST:ALT is >1.0

most heat stable ALP a.regan ALP b.liver ALP c.bone ALP d.intestinal ALP

Regan ALP

Measures amylase activity from reducing substrates? a.saccharogenic b.chromogenic c.amyloclastic d.enzymatic

Saccharogenic

True about lipase? 1.it is the most specific pancreatic marker 2.hemolyzed sample will cause false increase 3.cherry crandal is the reference method a.AOTA b.1, 3 c.1, 2 d.1 only

1, 3

complete the following LDH test: _____+ NAD-----LD->________+NADH a.wacker-pyruvate to lactate b.wrobleuski la due - lactate to pyruvate c.wacker - lactate to pyruvate d.wrobleuski la due - pyruvate to lactate

Wacker - lactate to pyruvate

True about LD6? 1.associated to AMI 2.converts methanol and ethylene glycol 3.elevated in drug hepetotoxicity and obstructive jaundice a.AOTA b.2,3 c.1,2 d.2 only

2, 3

This can be a tumor marker for untreated prostatic carcinoma? a.CK-MB b.CK-MM c.CK-BB d.AOTA

CK-BB

The following will increase in liver damage except? a.CK-MM b.ALT c.bilirubin d.NOTA

CK-MM

Ellman technique is used to determine what analyte? a.5N b.GGT c.CHS d.ACE

CHS (cholinesterase)

Hepatic coma is associated with? 1.to ammonia build up 2.deficiency of ornithine carbamoyl transferase a.both correct b.both incorrect c.1st statement d.2nd statement

Both correct

drug induced hemolytic anemia is caused by: a.G6PD deficiency b.Anti-P c.G6PD overproduction d.Anti D

G6PD deficiency

Normal plasma is composed of ______ water and _____ solutes a.95%, 5% b.97%, 3% c.93%, 7% d.98%, 2%

93% water, 7% solutes

The following causes hyponatremia except: a.nephrotic syndrome b.diabetes insipidus c.hepatic cirrhosis d.SIADH

Diabetes insipidus

Hyponatremia caused by true renal disease will have: a.urine sodium greater than 20mmol/L b.urine soidum less than 20mmol/L c.normal urine sodium level d.urine potassium greater than 20mmol/L

A. Urine sodium greater than 20mmol/L

panic values of potassium: a.3.5-5.2 mmol/L b.2-7 mmol/L c.2.5-6.5 mmol/L d.2-5.5 mmol/L

2.5-6.5 mmol/L

The ff. are true hyperkalemia except: a.addison b.hemolyzed sample c.acidosis d.low renin production

Hemolyzed sample

What is the level of chloride in post prandial specimen? a.high b.low c.not affected d.normal to high

Low

Patient with acute pancreatitis 1.will have increase TAG 2.will have decrease calcium a.both correct b.both incorrect c.1 only d.2 only

both correct

True about renal failure a.low phosphate b.high calcium c.high BUN and creatinine d.AOTA

High BUN and creatinine

Cotlove method is used to measure: a.chloride b.phosphate c.calcium d.bicarbonate

Chloride

The ff. is used to measure inorganic phosphorus? a.cotlove b.szass molybdate c.calmagite d.ammonium

Ammonium

What is the level of magnesium in hyperparathyroidism? a.low due renal excretion b.low due to intestinal blockage c.high due to intestinal absorption d.not affected - it’s calcium

High due to intestinal absorption

Second most abundant anion in the ECF a.chloride b.bicarbonate c.magnesium d.PO4

Bicarbonate

An anion gap of 10 after getting the Na, K, Cl, and bicarbonate level indicates: a.the patient is recovering from diabetic ketoacidosis b.the patient has hepatic cirrhosis c.the patient is positive for ingesting methanol d.the patient has elevated myeloma proteins

px is recovering from diabetic ketoacidosis

The ff. are blood buffers: a.bicarbonate and carbonic acid b.hemoglobin c.albumin d.AOTA

AOTA: bicarbonate, carbonic acid, hemoglobin, albumin

What is the normal ratio of bicarbonate to carbonic acid? a.10:1 - 20:1 b.20:1 c.1:20 d.1:10

20:1

The ff. will cause false decrease O2 reading except: a.protein buildup on membrane b.long standing specimen c.sepsis d.all of the above

Sepsis

What is the major disadvantage of transcutaneous electrode? a.long process b.expensive c.it may burn the skin d.patient may loss consciousness

It may burn the skin

On standing specimen for blood gas: 1.pH and pO2 decrease 2.pCO2 increases a.both are correct b.1 only c.both are incorrect d.2 only

Both correct (pH and pO2 decrease pCO2 increases)

What is the most common preanalytic error in blood gas assay? a.too much heparin b.failure to put the tube in ice c.too small syringe bore d.delayed test

Too much heparin

Leaving a specimen uncapped for blood gas measurement: a.false increase in pO2 b.false decrease pO2 c.false increase pCO2 d.NOTA

False decrease pO2

True about blood gas preanalytical requirement: 1.in arterial line blood - the first blood drawn in discarded 2.glycolysis leads to decrease blood pH 3.venipuncture can be used if O2 and pulmonary function is not assesed 4.liquid heparin is not acceptable due to dilutional effect a.AOTA b.1, 2, 3 c.1, 2, 4 d.2, 3, 4

aota

hepatic cirrhosis will lead to: a.respiratory alkalosis b.metabolic alkalosis c.respiratory acidosis d.metabolic acidosis

Respiratory alkalosis

what is the physiologic compensation for patient with botulism? a.hypoventilation b.H+ excretion c.hyperventilation d.HCO3- excretion

H+ excretion

CC REVA Flashcards

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