Flashcards in Cell Adaptation Deck (39)
Cause of disease
Development of disease.
Label or name disease
Damage; length of disability
Who is the father of pathology?
What two things do cells do when they are exposed to stress?
adapt or die
increase in size of cells and/or the organ (e.g. heart)
increase in number of cells in any organ/tissue; division
What are three etiologies of hyperplasia?
Prolonged hormonal stimulation can lead to?
Viral infection by papillomavirus are example of what type of hyperplasia?
List two pathogenesis causes of hypertrophy.
increased functional demand
hormonal stimulation (eg. thyroxin - thyroid medicine)
Low thyroid hormone causes (increase/decrease) in size of heart.
Shrinkage in the size of cells by loss of structural components caused by?
decreased work load
loss of innervation
diminished blood supply (vascular disease)
loss of endocrine stimulation
Reversible change in which one adult epithelial type is replaced by another adult type of epithelium. (columnar to squamous)
Cells have undergone atypical cytological alterations involving cell size, shape and orientation.
uncontrolled growth (eg. squamous cell carcinoma) [image]
An example of compensatory hyperplasia due to trauma is?
What is the human life expectancy?
Name two main factors that determine aging.
phagocytize incorrectly folded protein
Exposure to exogenous materials can accentuate aging by what process?
Intracellular accumulations exogenous materials
carbon pigment in lung
Where do carbon pigments circulate to?
hilar lymph nodes
List 6 examples of intracellular accumulations.
Chronic cor pulmonale is characterized by
dilated and hypertrophied ventricle
Multiple transfusions lead to what type of deposition?
Where does hemosiderin deposition occur?
kupfer cells of the liver
What is hemosiderosis?
excess deposits of iron
What controls calcium levels?
Differentiate between metastatic calcification and dystrophic calcification.
Metastic - occurs in normal tissue
Dystrophic - occurs in dead or injured tissue
Liver will undergo a fatty metamorphisis due to:
What is bilirubin an accumulation of? due to?
bile salt due to occlusion of hepatic duct or common bile duct
A patient with chronic cough and a 2 pack smoker for the past 30 years. Biopsy shows squamous metaplasia. What is the most appropriate interpretation?
irritant effect (metaplasia)
(cancer - neoplasia)
Man in involved in MVA. Left femoral artery is lacerated. Hematocrit is 12%. Which of the following tissues is most likely to withstand the impact?
What is hematocrit?
volume of RBCs in blood