cell cycle Flashcards

1
Q

what is G1

A

growth of cytoplasm and cell membrane. protein synthesis, organelles replicated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is G0

A

many cells stop dividing once they have specialised to their roles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what is S phase

A

DNA replication

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what is G2

A

growth and preparation for mitosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what is mitosis the division of

A

nucleus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what is cytokinesis

A

division of the cytoplasm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what makes stem cells different from normal body cells

A

they are not specific, have no jobs and have the potential to become any cell (differentiate)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what is the potency of a stem cell

A

the ability to turn into other cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

where is a totipotent stem cell found

A

a zygote - fertilised egg cell, and first few cells of the embryo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what can totipotent stem cells differentiate into

A

any cell type, including the ability to make a complete human

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

where is a pluripotent stem cell found

A

cells from an embryo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what can pluripotent stem cell differentiate into

A

any type of cell, not a whole organism though

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

where is a multipotent stem cell found

A

cells from the umbilical cord, bone marrow and other adult body tisses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what can a multipotent stem cell differentiate into

A

a few different types of cells, such as different types of bone and blood cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

where are chromosomes found in a cell

A

nucleus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what are chromosomes made of

A

DNA and histomeproteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

why are chromosomes important

A

carry DNA and the genetic code

18
Q

what are the chromosomes in a human nucleus arranged in pairs called

A

homologous pairs

19
Q

how many homologous pairs of chromosomes are their in a human

A

23 pairs or 46 single chromosomes

20
Q

what is a diploid cell

A

contains 2 copies of every chromosome in homologous pairs, one is paternal and the other is maternal

21
Q

what is a haploid cell

A

contain 1 copy of each chromosome, no homologous pairs and the only haploid cell are the gametes

22
Q

what are the stages of mitosis

A

interphase
prophase
metaphase
anaphase
telophase + cytokinesis

23
Q

what happens in interphase of mitosis

A

DNA is duplicated, diploid at this stage

24
Q

what happens in prophase of mitosis

A

chromosomes become visible, centrioles start to make the spindle, nuclear membrane breaks down

25
what happens in metaphase of mitosis
the chromosomes move to the equator of the cell. each chromatid is attached at the centromere to the spindle fibres made by the centrioles
26
what happens during the anaphase of mitosis
centromeres are pulled apart by the spindle fibres, chromatids are pulled to opposite poles of the cell
27
what happens during telophase of mitosis
the separated chromosomes uncoil, 2 new nuclei start to reform and this stage is followed by cytokinesis
28
how to work out the mitotic index
number of cells in mitosis/total number of cells
29
where does meiosis take place
reproductive organs to produce sex cells known as gametes
30
how many divisions are there is meiosis
2
31
what happens in interphase of meiosis
DNA is replicating and the chromosomes are not visible
32
what happens in prophase 1 of meiosis
the chromosomes become visible, made up of two sister chromatids attached at the centre of the centrome, the homologous pairs line up next to each other mixing the DNA - crossing over, at the end of prophase the chromosomes are shorter and the nuclear membrane disintegrates, spindle fibres are then formed and attach to the centromeres.
33
what happens in metaphase 1 in meiosis
the homologous pairs line up along the equator of the cell, random orientation of the chromosomes occur - line up randomly
34
what happens in anaphase 1 of meiosis
the homologous pairs begin to separate, each chromosome in a pair migrates to opposite poles, chromosomes still consist of two chromatids held together by their centrosomes - disjunction
35
what happens in telophase 1 in meiosis
the chromosomes reaches the opposite poles, a nuclear membrane forms around the chromosomes, each cell is a haploid - half the number of normal chromosomes.
36
what happens in prophase 2 of meiosis
the chromosomes condense and the spindle fibres appear and attach to the centromere, the nuclear membrane breaks down
37
what happens in metaphase 2 of meiosis
the chromosomes line up at the equator
38
what happens in anaphase 2 of meiosis
the centromeres splitting and the chromatids are pulled by the spindle fibres towards the opposite poles
39
what happens in telophase 2 of meiosis
new nuclear membranes reforms, each cell is haploid - half the net result of meiosis is the production of 4 cells from 1 cell each cell only containing one set of chromosomes which is half of original
40
which events in meiosis ensure that siblings end up with different combinations of their parents DNA
prophase 1 - crossing over metaphase 1 - independent assortment of homologous pairs