Cell Division/Cell Aging and Death Flashcards

(39 cards)

1
Q

What are the three stages of interphase?

A

G1, S, and G2

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2
Q

G1

A

growth and preparation for DNA replication

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3
Q

S phase (synthesis)

A

DNA replication

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4
Q

G2

A

growth and preparation for division of DNA

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5
Q

What are the phases of mitosis?

A

prophase, metaphase, anaphase, and telophase

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6
Q

Prophase

A
  • nucleus breaks
  • chromatin coils up into chromosome
  • spindle fibers appear
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7
Q

Metaphase

A
  • chromosomes line up in the middle of the cell
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8
Q

Anaphase

A
  • chromatid begins moving apart towards the cell’s poles
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9
Q

Telophase

A
  • Chromosomes begin to relax
  • Cleavage is formed
  • Nucleus is reformed
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10
Q

What does “pro-“ mean?

A

prepare

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11
Q

What does “meta-“ mean?

A

middle

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12
Q

What does “telo-“ mean?

A

end

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13
Q

Which to cell cycle phases overlap?

A

cytokinesis and telophase

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14
Q

DNA replication is also known as what?

A

DNA synthesis

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15
Q

DNA replication steps

A
  1. Parent DNA
  2. Parent strands unzipped
  3. Complementary strands synthesized
  4. 2 “sister” DNA copies
  5. Chromosome
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16
Q

What are the parts of a chromosome?

A

2 sister chromatids and centromere

17
Q

Chromatids

A

each of the two threadlike strands into which a chromosome divides longitudinally during cell division.

18
Q

What does each chromatid contain?

A

a double helix of DNA

19
Q

Centromere

A

the region of a chromosome to which the microtubules of the spindle attach

20
Q

What does DNA replication require?

A

regulatory proteins

21
Q

What is an example of regulatory proteins?

A

DNA polymerase matches with 50 nucleotides

22
Q

What do occasional mistakes in DNA replication?

23
Q

Mutations

A

random changes in DNA

24
Q

The cell cycle is typically what kind of process?

A

highly controlled

25
What is the result of disrupted cell regulation?
uncontrolled division
26
What is the result of uncontrolled division?
tumors
27
What are the two kinds of tumors?
benign and malignant
28
Benign tumors (noncancerous)
tend to grow slowly and do not spread
29
Malignant tumors (cancerous)
can grow rapidly, invade and destroy nearby normal tissues, and spread throughout the body
30
What are the two types of cell death?
necrosis and apoptosis
31
Necrosis
killed ny harmful agents/mechanical damage
32
What is the problem with necrosis?
with cellular lysis, the messy contents of the cell spills into the body
33
Cellular lysis causes what?
inflammation (swelling, redness, and pain)
34
Apoptosis
programmed cell death
35
What are the goals of apoptosis?
removal of damaged cells and normal development
36
What is an example of apoptosis's role in normal development?
removing the tail of the human embryo
37
What are the steps involved in apoptosis?
1. destruction of DNA/organelles 2. breaking into vesicles so that the contents doe not spill
38
What happens to the contents in the vesicles formed in apoptosis?
it is recycled by macrophages
39
What does "-phage" mean?
eat