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Flashcards in Cervical HPV CPC Deck (12)
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1

With regards to cervical cancer, HPV is...

Necessary, but not sufficient.

2

What are 4 risk factors for cervical carcinoma other than HPV infection? (2 are likely surrogates for HPV infection)

Multiple sexual partners: >6
Early age of first sexual intercourse.
Cigarette smoking.
Immunosuppression.

3

Do you have to have to have penetrative intercourse to contract HPV?

Apparently not. Can probably be spread by hands, any sort of contact.

4

3 outcomes of Squamous Intraepithelial Lesions (SIL)?

Regress, persist, progress (to carcinoma)

5

What do you do if Pap smear yields ASC-US in a woman over age 25?

Reflex HPV testing.

6

Cotesting can allow you space out testing intervals to every 5 years... in some cases, depending on the algorithm flow chart blah blah blah.

Yep.

7

Which HPV genotype is the most carcinogenic?

HPV 16
(HPV 18 is a little less so)

8

Do HPV infections (or at least the lesions thereof) sometimes clear?

Yep. And you can wait for that to happen before treating aggressively.

9

What cancer does Pap smears fail to screen for?

Adenocarcinoma.

10

What percentages of women with cervical cancer in the US have never had a Pap smear / not had one in the past 5 years?

50% have never had one.
10% not in the past 5 years.

11

What can you use to see evidence of transformation during colposcopy (not histology)?

Acetic acid -> causes transformed areas to turn white.

12

Will continue this when we have a better sense of what's going to be testable from the CPCs.

Sounds grand.