Ch 107 Pericardial surgery Flashcards
(36 cards)
What are the 2 layers of the pericardium?
Outer fibrous layer
Inner serous layer (closed mesothelial lined sac with parietal and visceral layers)
anatomy
- envelopes the heart; root of the aorta and pulmonary artery; and termination of the venae cavae, pulmonary veins, and azygos vein.
- visceral layer of serous pericardium known as the epicardium.
- The epicardium is attached firmly to the myocardium
- caudoventral apex of fibrous pericardium anchors ventrally at the muscular insertion of the diaphragm (sternopericardiac ligament)
- pericardium is supplied by paired pericardial branches of the internal thoracic arteries
List the functions of the pericardium
- Keeps the heart in position
- Restrains cardiac filling
- Enhances diastolic ventricular couplig
- Protects against atrial rupture
- Prevent spread of infection or neoplasia to heart from pleural cavity
- Provides a gliding surface for heart motion
pericardium is noncompliant and has a small reserve volume, intrapericardial pressure rises rapidly when the volume of its contents increases acutely.
With slow accumulation, the pericardium stretches
What does pericardial fluid contain?
What is a normal volume?
Pericardial fluid is an ultrafiltrate of the serum
- phospholipids for lubrication
- Protein 1.7-3.6g/dL
- Colloid osmotic pressure approx 25% of serum
Normal volume 1-15ml
What are the physiologic effects of cardiac tamponade? (7)
- Decreased cardiac output
- Increased central venous pressure
- Activation of compensatory RAAS and sympathetic adrenomedullary catecholamine release
- As atrial wall stretching is limited, atrial natriuretic peptide is not produced and therefore does not counteract effects of RAAS
- Increase in systemic venous and portal pressures causing jugular vein distention, liver congenstion, ascites and peripheral oedema
- Compression of coronary arteries causes poor myocardial perfusion
- Cardiogenic shock and death
cardiac tomponade
Cardiac tamponade:
Increased pericardial pressure → increased diastolic pressure → reduced stroke volume
- pericardial pressure = right ventricular filling pressure (R-sided tamponade)
→ left ventricular filling pressure (L-sided tamponade)
→ decreased cardiac output, increased systemic venous pressure
→ activation of RAAS → Na+ and H2O retention
+ sympathetic stimulation/catecholamine release → +ve ino- + chronotropic effects and vasoconstriction
- no atrial wall stretch → no atrial natriuretic peptide → no counteracting RAAS effects
→ increased systemic venous and portal pressure
→ jugular vein distension, liver congestion, ascites, peripheral oedema
+ compression of coronary arteries → myocardial hypoxia/ischemia
+ decreased cardiac output and arterial hypotension → cardiogenic shock → death
What is pulsus paradoxus?
variations of pressure quality associated with respiration phase
A variation in systolic arterial pressures up to 10mmHg from increasing venous return during inspiration in a relatively nonexpandable heart (due to pericardial effusion) causing intraventricular septal shift to the left, reducing CO
Can also be seen with obstructive lung disease, restrictive cardiomyopathy or hypovolaemic shock and is therefore not pathognomonic for pericardial effusion
Pulsus paradoxus:
Paradoxical arterial pressure variation during severe cardiac tamponade
Inspiration → decreased pericardiacl pressure and right ventricular pressure
→ venous return to right atrium, ventricle and pulmonary flow
- heart volume limited by pericardium – left intraventricular septum shifts to left
→ decreased left ventricular EDV, left heart output and arterial pressure
→ variation in systolic arterial pressure
The Beck’s triad, a classic indicator of cardiac tamponade, consists of three main symptoms: hypotension (low blood pressure), jugular venous distension (JVD) or bulging neck veins, and muffled heart sounds
What is the risk associated with partial pericardial defects?
Cardiac herniation
What have pericardial cysts been associated with?
PPDH
Other cases have been on a stalk at the apex of the pericardium
Suggests they result from entrapment of omentum, falciform ligament or liver in pericardium during development
What 2 syndromes can be associated with pericardial rupture?
pathophys
During healing, a stricture can develop causing vena caval compression
- Budd Chiari Syndrome: ascites and hepatomegaly
- Caval syndrome: Swelling of head and neck
Caval angiography for diagnosis. RIght 5/6th IC thoracotomy for resection of fibrotic sac +/- angioplasty with pericardial patch graft
severe ascites
rupture Tx
- caudal vena cava may appear to be kinked
- Caval angiography for diagnosis.
- RIght 5/6th IC thoracotomy for resection of fibrotic sac +/- angioplasty with pericardial patch graft
Pericardial Effusion
Etiology
- transudative: congestive heart failure, peritoneopericardial diaphragmatic hernia, hypoalbuminemia, or increased vascular permeability
- exudate: infectious or noninfectious pericarditis
- hemorrhagic: trauma, neoplasia, anticoagulant intoxication, or rupture of the left atrium secondary to mitral valve disease, idiopathic
What are the most common neoplastic causes of pericardial effusion?
HSA of right atrial appendage
Chemodectoma, usually along ascending aorta (brachycephalics most common)
mesothlioma (difficult to distinguish from idiopathic)
What breed is overrepresented for pericardial effusion?
Golden retreiver
What is an expected central venous pressure of a dog with pericardial effusion?
- Classic findings: muffled heart sounds, weak femoral pulses, tachycardia, and distention of jugular and peripheral veins.
- Chronic: CHF and acities
- acute manifestation because of acute bleeding
With cardiac tamponade, central venous pressure frequently exceeds 10 to 12 mm Hg
Describe the following ECG
Electrical alternans
- Amplitude of QRS and ST-T complexes changes from 1 complex to another due to heart swinging in fluid filled pericardial sac
- Strongly suggestive of pericardial effusion
Pericardial Fluid Cytology and Analysis
- usually do not differentiate the underlying cause
- serosanguineous pericardial effusions are rapidly depleted of clotting factors, fluid samples will not clot in an activated clotting time tube unless active hemorrhage is present
- cytology not reliable to dx neoplasia
What is the sentivity and specificity of echocardiogram for cardiac mass detection?
Neither CT/MRI found to improve detection of cardiac masses.
82 and 100%
- anechoic space between the epicardium and pericardial sac
- Collapse of the right atrium or ventricle during diastole
- allows visualization of cardiac masses or myocardial infiltration
RADS
- With chronic effusion and pericardial distention, the cardiac silhouette becomes globoid in shape
- pleural effusion, which often accompanies pericardial effusion
What can be measured in the plasma of dogs with pericardial effusion which is assoc with HSA?
Cardiac troponin I
- Conc over 0.25ng/ml 82% senstivite and 100% specific for cardiac HSA
Where do you perform a pericardiocentesis?
ECG > touche myocardium, premature complex will occur
Right 5/6th ICS with a 20g needle/catheter
pericardiocentesis - complications
adverse events in 10%:
- dysrhythmias,
- cardiopulmonary arrest
- continued bleeding
Blood vs effusion: effusate should not clot, and its PCV «_space;peripheral blood
20 g needle, extension set, three-way stopcock, and large syringe.