Ch 88 Salivary glands Flashcards
(45 cards)
four major salivary glands
parotid, mandibular, sublingual, and zygomatic
Parotid Gland
- positioned superficial to the vertical ear canal, rostrally by the masseter muscle and TMJ, caudally by the sternomastoideus and cleidocervicalis muscles, ventrally by the mandibular salivary gland
- deeper surrounding structures, including, but not limited to, the facial nerve, maxillary and temporal arteries, internal maxillary vein
- duct: travels over the lateral aspect and ventral third of the masseter muscle and opens into the oral cavity at PM4
- arterial supply: parotid artery, a branch of the external carotid artery
Zygomatic Gland
- ventral and rostrolateral to the globe and medial to the zygomatic arch
- One major and up to four minor salivary ducts
- major duct opens at last upper molar
- supplied by a branch of the infraorbital artery
Mandibular and Sublingual Salivary Gland
- intimately associated and thus considered anatomically as a pair.
- two glands have a common capsule
- mandibular gland lies on medial aspect of the linguofacial and maxillary vein junction, mandibular lymph nodes ventral surface and the medial retropharyngeal lymph node and larynx on its medial surface
- duct: exits into the oral cavity at the sublingual caruncle
- major blood supply: branch of the facial artery
- sublingual salivary gland is composed of monostomatic and polystomatic portions.
- polystomatic salivary tissue consists of small clusters of glandular tissue rostral to the lingual nerve that typically empty directly into the oral cavity.
- duct courses alongside the mandibular duct and usually exits at the sublingual caruncle
- blood supply: glandular branch of the facial artery and sublingual branch of the lingual artery
Minor Salivary Glands
- buccal, labial, lingual, tonsillar, palatine, and molar
- molar gland is well developed in cats and is located just deep to the buccal mucosa at the angle of the mandible.
List the functions of saliva
Lubricate ingesta
Facilitates making a food bolus
THermoregulation
Cleansing
Buffering
Reduction of bacterial growth
Protection of oral surface epithelium
Describe the two phases of saliva production
Phase 1: Acinar cells absorb Na which draws water in, producing Na-rich saliva
Phase 2: Saliva enters the collecting ducts. Active reabsorption of Na with secretion of HCO and K. Occurs mainly in intralobular duct. Forms saliva rich in bicarb and K
WHat structures are closely associated with the parotid salivary gland?
Facial nerve
Maxillary and temporal arteries
Internal maxillary vein
Regions surround external acoustic meatus and stylomastoid formen
Where so the parotid and zygomatic salivary glands enter the oral cavity?
Parotid: Small papilla at the level of the upper 4th premolar
Zygomatic: Caudolateral aspect of last upper molar
What is the anatomical delineartion between the monostomatic and polystomatic portions of the sublingual salivary gland?
the lingual nerve
- Caudal is monostomatic
- Rostral is polystomatic
Secretions from what glands have a higher proportion of mucus?
Sublingual and zygomatic
What causes the stimulation of saliva production?
Autonomic nervous system
- Stimulation of parasympathetic nervous system stimulated the production of salvia by vasodilation of blood supply and by stimulation of cyclic guanosine monophosphate (cGMP) which directly upregulates the acinar cells
What is sialadenosis?
Non-inflammatory, non-neoplastic bilateral swelling of the salivary glands. Most common mandibular glands
What is the treatment for sialadenosis?
Phenobarbital 1-2mg/kg PO BID.
Clinical signs should improve within 1-2 days. This response may support a diagnosis of limbic epilepsy (cause of sialadenosis is unknown)
List 2 proposed caused of noninfectious sialadenitis / necrotising sialometaplasia
Hyperstimulation of the vagus nerve, resulting in a neural reflex syndrome similar of hypertrophic osteopathy. Can have concurrent oesophageal or GI disease
Limbic epilepsy - response to phenobarbital reported
How can you differentiate sialadenitis from sialadenosis?
What breeds are predisposed to sialadenitis?
Sialadenitis will cause pain upon palpation of effected glands and vomiting
Terrier breeds are predisposed to sialadenitis
What breeds are predisposed to sialocoeles?
Poodles, GSD, Australian Silkies and Dachshunds
four main presentations are:
- exophthalmos (zygomatic sialocele)
- labored breathing (pharyngeal sialocele)
- dysphagia (sublingual sialocele or ranula)
- intermandibular or cranioventral cervical swelling (cervical sialocele)
diagnosis
- fluid-filled mass that contains a viscous, honey-colored, clear or blood-tinged fluid
- Cytological: moderate numbers of nondegenerate nucleated cells, homogenous pink- to violet-staining mucin, foamy Macrophages
Zygomatic Sialoceles
- exophthalmos, protrusion of the third eyelid, or a painless orbital swelling
- sialography, cross-sectional imaging
Tx: sialadenectomy or Use of a sclerosing agent
Pharyngeal Sialoceles
- caudal dorsal or lateral pharynx, just rostral to the level of the epiglottis
- Miniature Poodles and male overrepresented
- concurrent ipsilateral cervical sialoceles in 43% of affected dogs
- Pharyngeal sialoceles pose a risk for airway obstruction
tx: Immediate drainage or temporary tracheostomy if respiratory distress, marsupialisation and removal of mandibular and sublingual gland-duct complex
Sublingual Sialoceles
- Sublingual sialoceles, also called ranulas, likely result from leakage of the rostral sublingual salivary glands or duct
- esulting in difficulty with eating
- ranula should be drained and marsupialized into the oral cavity. Incomplete removal of the sublingual salivary chain can result in recurrence
Cervical Sialocele
- fluctuant in nature, nonpainful, and occasionally changes in size, Diagnosis is made primarily by aspirating
- mucin-specific stain, such as periodic acid–Schiff, help to confirm saliva
- radiographs, sialography, CT, MRI, ultrasonography, culture, and biopsy
- ddx branchial cleft cyst can be differentiated from a sialocele > demonstration of a true secretory lining on histo
- most cervical sialoceles originate from the sublingual gland-duct complex
- determining side: chronic, placed in dorsal recumbency > fluid accumulation usually displaces laterally to the affected side.
- may require sialography, CT, MRI, or an exploratory surgery
- If any question remains, bilateral sialadenectomy can be performed (dry mouth is not expected)
- Conservative treatment of sialoceles > high rate of recurrence
What is the reported rate of recurrence of sialocoele after surgical removal of the gland?
5%
complications: seroma, infection, recurrence, sublingual swell, bleeding