Ch 117 urethra Flashcards

(73 cards)

1
Q

List the layers of the urethra

A

Mucosa (transitional > squamous epithelium)
Submucosa
Muscularis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Describe the urethra muscularis in the male and female dogs and cat

A

Male dog:
- Inner longitudinal smooth surrounded by outer circumferential striated
- Striated muscle is the distal 2/3rds of the urethra
- Striated mostly Type II fast twitch, some Type I slow twitch

Male cats:
- 3 layers of smooth muscle - inner longitudinal, middle circumferential, outer longitudinal

Female dog:
- Three smooth muscle layers as male cats
- striated muscle fibers in the distal third > Smooth muscle essentially absent in terminal urethra
- Prominent sphincter of striated muscle at external urethral orifice

Female cat:
- Significantly more smooth muscle and significantly less striated urethral sphincter than female dog

striated muscle > innervated by pudendal n.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Anatomy

A

Male
- divided anatomically into pelvic and penile components
- subdivided into preprostatic and prostatic
- penile component begins at the ischial arch and is surrounded by the corpus spongiosum
- Gonadectomy or age at time of gonadectomy does not affect urethral diameter in mature male cats

female
- urethra of female dogs contains significantly more collagen and less muscle than male dogs
- increase in the proportion of collagen and reduction in muscle in the urethra of gonadectomized female dogs, compared with intact dogs
- findings suggest that steroidal hormones may influence the morphology of the canine urethra

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the urethral diameter of male cats at the level of the bulbourethral glands compared to the penile urethra

A

Bulbourethral gland 1.3mm
Penile urethra 0.7mm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Initial management of patients with suspected urethral obstruction should include:

A
  • evaluation of hemodynamic status,
  • correction of metabolic derangements,
  • urinary diversion
  • postobstructive diuresis (once unblocked)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the theorised mechanism of hypothermia in cats with urethral obstruction?

A

Reduction in the thermoregulatory set point in the hypothalamus secondary to uraemia
Or secondary to volume depletion and shock

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the time frame for renal decompensation and death in aminals with complete urethral obstruction?

A

Renal decompensation within 24hr
Death 3-6d

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What fluid is most efficient for correcting electrolyte derangement with urethral obstruction?

A

LRS

alkalinizing effect helps to drive potassium ions intracellularly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

List options and mode of action of each option for the treatment of hyperkalaemia

A

10% Ca Gluconate
- Increases threshold for cardiac myocyte depolarisation. 0.5-1.5ml/kg IV over 5-10 min, last 30-60min

IV dextrose +/- regular insulin
- Drived K intracellularly by cotransport. Lasts 2-4hr

Na Bicarb
- Enables H ions to move extracellularly in exchange for K. Only used if severe acidosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

ECG changes

A
  • spiked T-waves
  • depressed R-waves,
  • prolonged QRS and PR intervals and ST segment depression,
  • smaller and wider P-waves with a prolonged QT interval,
  • atrial standstill,
  • eventually wide QRS complexes and ventricular arrhythmias
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

unblock

A

catheter are unsuccessful:
- retrograde urohydropulsion under general anesthesia
- improved by lubricating agents, topical anesthesia, or coccygeal epidural
- bladder decompression can be maintained by intermittent cystocentesis
- placement of a cystostomy tube (minimally invasive inguinal approach)
- a guide wire can be passed through the body wall and antegrade out the urethra

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

diagnosis

A

RADS
- radiopaque urinary calculi,
- Positive-contrast retrograde urethrography (best for suspected tear)
- retrograde vaginourethrocystography in females
- Negative (air)-contrast radiography is contraindicated with suspected lower urinary tract trauma
- Ideally, fluoroscopy should be performed
- gradual withdrawal of the catheter or use of a voiding cystogram
- cannot be catheterized, a normograde urethrocystogram

ultrasound limited, CT/MRI not well described

Cystoscope
- evaluation and treatment of a variety of lower urinary tract diseases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

List the critical factors which effect urethral healing

A
  • Mucosal continuity
  • Urine extravasation

If a strip of mucosa is left intact and urine is diverted, the urethral mucosa can regenerate within 7 days

exposure of submucosal tissue to urine may promote formation of scar tissue, reducing the elastic qualities

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Urethral Healing

A

partial
- Conservative therapy is indicated
- mucosal continuity and the flow of urine is diverted

complete
- Primary surgical repair or permanent urinary diversion is indicated
- urethral mucosa may retract, and fibrotic tissue may ultimately bridge the gap and obstruct
- ventral midline celiotomy/pubic osteotomy followed by antegrade (through the bladder) or retrograde urethral catheterization may be required to identify the distal end of the proximal urethral segment
- Diversion (cystostomy tube or indwelling urethral catheter) is recommended for 3 to 5 days to minimize the risk for urethral stricture
- size 4-0 or 5-0 USP
- tensile strength of poliglecaprone 25 (Monocryl; Ethicon) is lost at a relatively rapid rate when immersed in a container of urine
- presence of an indwelling catheter can promote inflammation and ascending infection
- Some reduction in urethral luminal diameter at the site of surgical repair is anticipated, regardless of whether or not a catheter is left in place after surgery.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

How much narrowing of the urethral lumen occurs before clinical signs occur?

A

60%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Urethrotomy

A
  • commonly indicated for removal of calculi
  • if can be dislodged and flushed back into the bladder, cystotomy is preferable to urethrotomy
  • DOGS prescrotal region, because calculi most often lodge at the base of the os penis
  • optimal location for urethrotomy because of the superficial position of the urethra and paucity of surrounding cavernous tissue
  • Perineal and prepubic urethrotomy can be performed
  • minimally invasive perineal urethrotomy can be performed under simultaneous ultrasonographic and fluoroscopic guidance > for insertion of a scope
  • Hemorrhage, especially associated with urination, is the most common complication
  • Urethral stricture is an uncommon
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Prescrotal Urethrotomy

A
  • prepuce should be irrigated with dilute antiseptic
  • Retrograde urethral catheterization is used to facilitate identification of the urethra and determine the level of the obstruction
  • 2-cm incision is made on the ventral midline immediately caudal to the os penis
  • paired retractor penis muscles are retracted laterally.
  • The urethra and surrounding corpus spongiosum is identified as a purple
  • Profuse hemorrhage is expected > cotton tip or ellulose surgical spears
  • Calculi are removed, and the urethral catheter is advanced proximally into the bladder.
  • A cystotomy can be performed
  • The urethra is flushed antegrade and retrograde

alternative
- modification of this technique is urethrotomy through the glans penis

closure?
- second intention healing, urination will occur from the urethral incision for 10 to 14 days until the wound heals (petroleum-based jelly may reduce urine scalding and scrotal dermatitis)
- if haemorrhage profuse may need closure
- primary closure 4/0

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

List the options for a urethrostomy

A

Scrotal
Perineal
Transpelvic
Subpubic
Prepubic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

How long should the incision in the urethra be for a urethrostomy?
How much contraction is expected during healing?

A

2.5-4cm long (approx 5-8x urethral diameter)
Will contract by 1/3-1/2 during healing

stoma will contract by one-third to one-half of its original length

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Hows does a continuous suture in a scrotal urethrostomy effect post-op haemorrhage?

A

Decreases time of active haemorrhage from 4.2d to 0.2d

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Scrotal Urethrostomy in Male Dogs

A
  • preferred over perineal urethrostomy because the urethra is relatively superficial and wide at the level of the scrotum, and less hemorrhage occurs
  • urethral mucosa is incredibly thin and somewhat fragile, and tissue handling must be gentle and precise
  • Apposition can often be improved by using a two-step process during suture placement
  • A urinary catheter is placed
  • sutures are placed from the tunica albuginea to the subcutaneous tissue on either side of the intended urethrostomy site to maintain the penis and urethra in a superficial position
  • incision is centered on the urethral midline
  • Use of magnification may be beneficial,
  • Elizabethan collar should be maintained for 2 to 3 week
  • Bleeding associated with urination occurs for an average of 3 to 5 days after urethrostomy and is usually self-limiting.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

complications

A
  • haemorrhage
  • Intermittent urine scald,
  • recurrent urinary tract infections,
  • recurrent obstruction from calculi
  • stricture (uncommon)

each occurred in 10% of dogs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What is the name of the standard cat PU technique?

A

Wilson and Harrison technique

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

What ventral structures need to be transected during a cat PU?

A

Ventral penile ligament
Attachment of ischiocavernosus muscles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
To what level is the penis freed and the urethra incised in a cat PU?
To the bulbourethral glands
26
PU sx
- ischial attachments are sharply transected with scissors or electrocautery or detached with a periosteal elevator. - retractor penis muscle (or its remnant in castrated males) is identified on the dorsal aspect of the penis and excised - Halsted mosquito forceps > new stoma should easily accommodate - Precise and tension-free apposition, 4/0 or 5/0 - dorsal sutures are critical to maximize stoma size and prevent urine leakage - STUDY: No significant differences in postoperative complications were reported when closure was performed with a simple continuous pattern - distal extent a washboard to the skin - postoperative period shredded paper + petroleum jelly is applied to the peristomal region - Perineal urethrostomy can be easily performed in dorsal recumbency
27
What is the expected outcome after PU surgery?
**12.8-25% early complications (haemorrhage, stricture, extravasation)** - Strictures: secondary to excessive tension at the point of the bulbourethral glands - extravasation typically results from imprecise urethrocutaneous apposition (can cause inflamm fibrosis, necrosis , slough) **Long-term complications 28% (UTI, recurrent FLUTD)** - attributed to ascending bacterial migration because of urethral shortening - risk for infection is not increased in normal cats > indicating underlying uropathy Good long term outcome (88%) but most will require ongoing management of underlying uropathy
28
What muscles are elevated in the approach for a transpelvic urethrostomy?
Gracilis External obturator
29
Transpelvic Urethrostomy in Male Cats
- employs a caudal ischial ostectomy to allow access to, and ventral opening of, the pelvic urethra 15 to 18 mm cranial to the bulbourethral glands - useful for revision of failed PU - ventral approach reduces the risk for iatrogenic damage to the dorsal innervation - Bone rongeurs are used to remove a section of the caudal ischium, 12 mm in length and 10 mm in width
30
outcome TU
- minor long-term complications were noted, including recurrent signs of FLUTD in 2 cases and peristomal or pelvic limb urine staining - low incidence of stricture was attributed to the fact that the stoma was positioned in the wider pelvic urethra
31
What muscles require elevation in the approach for a subpubic urethrostomy?
Gracilis Adductor | prepubic tendon is incised
32
Subpubic Urethrostomy in Male Cats
- pubic osteotomy and creation of a pubic flap to provide access to the postprostatic urethra - urethra tunneled subcutaneously to form a stoma in a subpubic location, caudal to the inguinal fat pads - anecdotally is associated with less complications than prepubic - T-shaped flap osteotomy - approximately 3 cm caudal to the pubic brim. The urethra is tunneled through the subcutaneous tissue, exteriorized
33
Prepubic Urethrostomy
- involves creation of a stoma on the ventral midline immediately cranial to the brim of the pubis - In male dogs the stoma can be created in a parapreputial location or potentially into the preputial cavity - proximal urethra is identified and isolated, taking care to avoid traumatizing associated innervation and vascular supply - preserving the maximal amount of normal urethra available to optimize continence > close to vagina or distal to prostate - the urethra can be exited through a separate paramedian stab incision - urethra is spatulated with a 5- to 10-mm incision - continence may be maintained if the sphincter and innervation are preserved
34
Which urethrostomy has the highest rate or morbidity and complications?
Prepubic - 6/16 cats incontinent (37%) - Significant peristomal skin irritation - Stricture, kinking or compression or urethra - recurrent UTI
35
List options for reinforcement of a tenuous urethral anastomosis
Rectus abdominus flap Internal obturator flap Omentum
36
What is the prognosis after urethral resection and anastomosis?
Guarded - Some degree of stenosis is expected
37
What is the most important factor in minimising stenosis after a urethral anastomosis?
Urinary diversion - either via u-cath or tube cystostomy
38
Urethral Anastomosis
- indications: trauma, stricture exicision - access depends on locations i.e celiotomy, eplic osteotomy etc - suture is placed in the bladder apex, and the bladder is retracted cranially to provide access to the urethra. - use catheters - minimize the risk for neurogenic or vascular trauma - ensuring that both mucosa and submucosa are included in each bite. - Preplacement of sutures, particularly on the dorsal surface - reinforce R&A is concerned
39
What is hypospadia? What breed is overrepresented?
Failure of the fusion of the urogenital folds resulting in incomplete formation of the penile urethra Bostron Terriers overrepresented
40
Tx hypospadia
- evaluated for concurrent urogenital abnormalities, most commonly cryptorchidism, but also underdevelopment of the testes, scrotum, prepuce, or penis - urethrostomy proximal to the site is typically recommended.
41
What is epispadia? What condition is often seen concurrently?
Failure of fusion of the dorsal penile urethra. - May occur with concurrent bladder exstrophy (portions of bladder and abdominal wall absent and bladder appears inside-out)
42
List the 2 broad types of urethral fistulas
Urethrorectal Urethrocutaneous
43
List the surgical options for a double urethra
Open surgical removal Cyanoacrylate and coil embolisation
44
Urethral Obstruction
- incidence 18% to 58% of male cats with lower urinary tract disease - uroliths, urethral plugs, neoplasia, granuloma, bladder displacement or herniation, strictures, trauma, prostatic disease, and idiopathic - dogs: often lodge immediately caudal to the os penis or at the ischial arch - cats: distal third of the urethra neoplasia - trigone of the bladder is most commonly affected, invade the proximal urethra. - Cystoscopic electrosurgical transurethral resection showed promise for treatment of male dogs with urethral invasion - because of discouragingly high complication rates and minimal impact on survival times associated with curative-intent therapy, palliative commonly performed
45
What % of bladder and urethral tumours are malignant in dogs and cats?
97%
46
What is the reported incontinence rate of dogs and cats after urethral stenting?
26% dogs 50% cats
47
Urethral Trauma
- iatrogenic catheterization or from external blunt or penetrating trauma - associated with pubic fracture - cats: iatrogenic usually postpelvic urethra (78%), external trauma intrapelvic urethra (74%) - Uroperitoneum or subq cellulitis - urinary tract injuries were suspected during physical examination in only one-third of animals that were subsequently found to have urinary tract trauma - Primary anastomoses appeared to carry a reasonable risk for stricture three main options for treatment: 1. temporary urinary diversion and second intention healing 2. primary repair 3. permanent urinary diversion via urethrostomy or a cystostomy tube
48
List causes of urethral stricture
Trauma Obstruction Inflammation Malignancy Iatrogenic surgical
49
List the treatment options for a urethral stricture
* Urethrostomy (proximal to the affected site) * Resection and anastomosis * Balloon dilatation * Stent * Urethral replacement (Aortic stent graft, Rectus abdominus axial pattern flap, ileal segment, oral mucosal grafts +/- adipose-derived stem cells and polyglycolic acid scaffold)
50
What can cause benign mass-like lesions within the urethra?
Proliferative urethritis Fibroepithelial polyps
51
What breed are overrepresented for urethral prolapse? underlying cause? What are the surgical options? Recurrence rate? | protrusion of distal urethral mucosa through external urethral orifice
**English Bulldogs** unknown, related to abnormal development of the urethra + increased intraabdominal pressure dt labored breathing, dysuria, or sexual excitement Sx Options: - Reduction and purse-string - Urethropexy - Resection and anastomosis (torniquet, incision is limited to half the urethral circumference to prevent retraction) Long-term recurrence 57% | 39% of dogs demonstrated postoperative hemorrhage
52
Application of preputial tube-flap urethroplasty to establish a neourethra in a male dog with complications after preputial urethrostomy Satanyasuwan 2024
A longitudinal flap was raised from the prepuce and anastomosed to the end of the previously cut urethra to create a neourethra and reduce tension at the urethrostomy site. The dog had excellent symptom scores, and urinated from the prepuce without difficulty in a manner resembling physiological urination.
53
Surgical treatment of canine urethral prolapse viavia urethropexy or resection and anastomosis D. Healy 2024
79 canine urethral prolapse: urethropexy vs resection and anastomosis 63/79 = brachycephalic urethropexy (n=44), R&A (n=27) and combined (n=8). Minor complications (51.9%): urethropexy (43.2%), R&A (66.6%), combined (50%). Major complications (29.1%) > Recurrence urethropexy (38.6%), R&A (11.1%) RA > no significant difference if simple continuous or interupted RA lower recurrence rate in comparison to urethropexy Minor complications and bleeding more common/longer duration following RA
54
Comparison of urethral length and orifice diameter in cats undergoing transpelvic or subpubic urethrostomy for perineal urethrostomy revision (cadaveric study) Sieglinde David 2023
urethral length and orifice diameter: PU vs transpelvic vs subpubic urethrostomy (cadaveric study) Stenosis complication > 12–17% of male cats The TPU > 1.5-times longer residual urethral length than SPU Relative to the initial urethral length: PU 24%, TPU 36% and SPU 56%, urethral orifice diameter: not statistically significantly different between TPU and PU and SPU TPU preserves a significantly longer urethral length and requires less tissue dissection risk of UTI, urinary dermatitis and urinary incontinence might be less following TPU than SPU.
55
# idiopathic functional urinary outflow tract obstruction iFUOTO is a condition in dogs characterized by difficulty urinating and a large amount of residual urine in the bladder, without any obvious physical blockage or clear neurological disorder directly causing these signs at the onset. The term reflects the unknown cause of this functional obstruction FUOTO is characterized by the absence of these clear neurological deficits at the onset of urinary signs Dogs with iFUOTO commonly present with stranguria (straining to urinate). Many dogs (45% in this study) also experience overflow urinary incontinence, which is often diagnosed based on the presence of a large bladder after the dog attempts to void. A large postvoid residual volume (PVRV), meaning a significant amount of urine remains in the bladder after urination, previously referred to as reflex dyssynergia or detrusor urethral dyssynergia (DUD) iFUOTO is essentially a diagnosis of exclusion, meaning it is considered after ruling out mechanical obstructions and primary acute neurological diseases
56
# Urinary catheterisation of female dogs: a comparison between three Urinary catheterisation of female dogs: a comparison between three techniques for catheter placement AE Tipler 2020 | AVJ
Visual with speculum (SPEC), Blind Palpation (BP) and catheterisation with NCD on three sizes of dog Median times to catheterisation were 300 s (IQR 261–417 s) with the SPEC method, 420 s (IQR 253–545 s) with the NCD method and 725 s (574–1032s) with the BP method. Both SPEC and NCD methods were significantly faster compared to the BP method The novel urinary catheterisation device may provide a simpler method of visualisation of the urethral papilla and may provide a more sterile way of placing the catheter, although further investigation is needed to confirm this.
57
A novel two-catheter method for urethral catheterization improves success rates of urethral catheterization in female dogs and cats weighing less than ten kilograms Josephine A. Dornbusch 2023
38 female cats and dogs weighing less than 10 kg were prospectively enrolled The 2-catheter technique was more successful than the traditional method (60.5% and 34.2%, respectively) a red rubber catheter (Sovereign feeding tubes; MWI Animal Health; 10-Fr for cats, 18-Fr for dogs) was introduced into the vestibule and advanced cranially until gentle resistance was met at the cervix MILA foley indwelling urinary catheter (Foley Catheters with wire stylet; MILA International; 5-Fr for cats, 8-Fr for dogs) was passed into the vestibule, directed along ventral midline at approximately a 45-degree angl
58
Preputial urethrostomy with preservation of the local anatomy in 4 dogs Thomas Giansetto 2022
Preputial urethrostomy in 4 dogs > anastomosis of the pelvic urethra with the preputial mucosa after caudal laparotomy, without dissection of the prepuce or amputation of the penis None dysuria, urinary tract infection, or dermatitis dogs showed signs of urinary incontinence from 15 days to 1 month postoperatively, which persisted 50% incontinence > slight urinary incontinence when the dog was excited (Their urethra was transected just caudal to the prostate)
59
Outcomes and postoperative complications after transpelvic urethrostomy used as first-line surgery in 38 male cats with obstructive lower urinary tract disease Caroline Dumartinet 2022
complications: short term 18% - idiopathic LUTD and stenosis (16%) most common long term 34% - LUTD, UTI, stenosis - mortality rate: 5% - outcome: 91% free of clinical signs at the end of the study - stomal stenosis → owner dissatisfaction due to number of revisions - acceptable first-line tx – [no benefit as first line over traditional PU?]
60
Prazosin administration increases the rate of recurrent urethral obstruction in cats: 388 cases David S. Conway 2022
Urethral relaxation has largely been attempted pharmacologically with medications such as α1-adrenoceptor antagonists, acepromazine, and benzodiazepines. Inflammation, thought to be a key contributor to the pathophysiology of UO, has also been targeted via systemic NSAID administration and intravesicular glycosaminoglycan administration. 5,6 However, none of these pharmaceutical strategies have been shown to be reliable in achieving reductions in rUO in smaller clinical studies, and a highly effective method to prevent rUO remains elusive. Prazosin potential action as a urethral smooth muscle relaxant 302 (78%) cats received prazosin, while 86 (22%) did not Prazosin administration increased the likelihood of recurrent UO by 14 days;
61
Modified prepubic urethrostomy with body wall tunneling: Description of technique and long-term outcome in eight male cats Luca Bresciani 2022
Modified prepubic urethrostomy with body wall tunneling: 8 cats short oblique tunnel within the rectus abdominis muscle fibers to increase internal urethral sphincter pressure to maintain continence - resolution of obstruction, creation of patent stoma and long-term continence no intraoperative complications 2 cats revision > abdominal fat around the stoma, causing a partial stomal obstruction
62
Comparison of surgical indications and short- and long-term complications in 56 cats undergoing perineal, transpelvic or prepubic urethrostomy Maheeka Seneviratne 2021
- indications: PU – feline idiopathic cystitis most common; PPU – trauma most common - urethrostomy technique associated with cause and imaging findings - complications: overall short-term: 33/55 (60%); long-term 11/30 (36.7%) - long-term complications more likely with PPU – incontinence ((13.3%) cats with PPU) and dermatitis - outcome: short-term mortality 5.6%, long-term mortality 13.3% - independent of sx tech - 93% good QOL overall - PPU was associated with a higher long-term complication rate of incontinence than PU and TPU low numbers of cats in the TPU and PPU groups
63
Buccal mucosal graft urethroplasty in male cats with traumatic complete urethral rupture Wanchart Yippaditr 2022
Buccal mucosal graft urethroplasty with traumatic rupture: 15 male cats buccal mucosa formed into a tubule by use of an 8F indwelling catheter as support > graft was connected to both ruptured ends of the urethra Risk inadequate vascularization > omentum wrap perofrmed 14 > membranous urethral rupture (between prostate and penile urethra), 1 prostatic urethra rupture 13 cats recovered well (86%) > 6 months no stricture or leakage 2 > urethral stricture and underwent second surgery 1 cat had incontinency bladder mucosa, however > buccal mucosa lower stricture rate and graft shrinkage. experimentally induced defects 20% to 30% of urethral length can be apposed without tension
64
Effect of intraoperative positioning on postoperative neurological status in cats after perineal urethrostomy Pavel Slunsky 2019
Effect of intraoperative positioning on postoperative neurological status in cats after PU 10-30% occurance post-op > perineal reflex was significantly decreased and spinal pain significantly increased 24 h after surgery. low-grade positioning-dependent nerve injury as described in human medicine. no positioning method was proven to be superior All considered normal 14 days after surgery
65
Clinical outcomes of 28 cats 12–24 months after urethrostomy Reginaldo P Sousa-Filho 2020
long-term clinical outcomes and quality of life of cats having undergone perineal urethrostomy (PU) or prepubic urethrostomy (PPU). The overall complication rates of PU and PPU were 31.8% and 83.3%, respectively. Recurrent urinary tract infection (UTI) and urine scald dermatitis were less frequent in PU than in PPU cats (UTI 22.7% vs 66.6%; dermatitis 4.5% vs 83.3%). Bacteriuria was present in 77.2% and 100% of PU and PPU cats, respectively. Owner satisfaction rates were excellent in 81.8% of PU and 33.3% of PPU cases. PPU limited to cases in which standard techniques for PU cannot be performed, owing to the potential for recurrent complications and lower owner satisfaction.
66
Buccal mucosal graft urethroplasty in five male dogs with penile urethral stricture at the bulbus glandis Athipot Jareonsuppaperch 2024
Prospective. Buccal mucosal graft urethroplasty in five male dogs penile urethral strictures at the bulbus glandis > patch graft All dogs were able to urinate normally after catheter removal No major complications All owners scored the urinary function as excellent Tubular grafts > fail due to inadequate graft take, as they are not circumferentially surrounded by vascularized tissue patch grafts > provide better outcomes than tubular owing to greater blood supply alternative: stent, balloon dilation > neither great success
67
Management of incontinence following pre-pubic urethrostomy in a cat using an artificial urethral sphincter M. K. Eayrs 2021
An artificial urethral sphincter mechanism, with subsequent incremental inflation of the cuff 6 weeks later, resulted in complete resolution of clinical signs, return to normal urinary function and excellent quality of life. The cat was still continent at 5-year follow-up.
68
Multicenter evaluation of decompressive cystocentesis in the treatment of cats with urethral obstruction Erica L. Reineke 2021
whether decompressive cystocentesis facilitates urethral catheterization in cats with urethral obstruction. 88 male cats DC did not increase risk for urine leakage and uroperitoneum DC did not improve time to place the urinary catheter or ease good for emergeny if can’t catheterise for some reason. i.e. too unstable for GA
69
Penile urethral resection and anastomosis augmentation with regional tissue tension relieving technique: A cadaveric mechanical study and clinical outcome in two dogs Judith Bertran 2021
Penile urethral R&A augmentation: A cadaveric study and 2 cases augmentation improved the tensile properties of penile RA in normal cadavers may help prevent stricture or leakage secondary to tension circumferential suturing of tunica albuginea to the anastomosis
70
Evaluation of urethral orifice crosssection dimensions following perineal urethrostomy in male cats U. Segal 2020
occurrence of urinary obstruction/stricture 5/24 (20%) at mean 92±25d post-op - estimations of cross-sectional area by size of largest urinary catheter inserted - significant decrease in urethral orifice cross-sectional area (0.15±0.09mm2) at 12d post-op - probability of post-op obstruction: immediate CSA ≤8Fr = 44%; >8F – 6% - recurrence of obstruction in 3/3 cats with immediate CSA 6F Contraction of the urethral orifice diameter is expected during the wound healing phase. Post-operative urinary obstruction is more likely in cases where LUCi < 8Fr.
71
Retrospective multicentric study comparing durations of surgery and anesthesia and likelihoods of shortand long-term complications between cats positioned in sternal or dorsal recumbency for perineal urethrostomy Alicia K. Nye 2020
Retrospective. cats positioned sternal vs dorsal for PU 247 cats Patient position was not associated with durations of surgery and anesthesia for PU, even if a concurrent cystotomy was necessary. patient position was not associated with the likelihood of complications. dorsal position > negates repositioning for cystotomy, minimizes pressure on the diaphragm dorsal recumbency may also be superior to sternal > sagittal diameter of the lumbosacral and sacrococcygeal segments of the vertebral canal is not as reduced
72
Outcomes following balloon dilation for management of urethral obstruction secondary to urothelial carcinoma in dogs: 12 cases (2010–2015) Sangho Kim 2019
balloon dilation for urethral obstruction secondary to carcinoma in dogs: 12 cases Improvement in clinical signs after initial procedure > 9/12 dogs. Recurrence in 5 dogs 48 to 296 days Complications: hematuria, urinary incontinence, and dysuria; these resolved within a few days after treatment. dogs of the study population
73
ACVIM concensus statement