Ch. 12: Reye Syndrome

Question 1

What is Reye syndrome?

Answer 1

A life threatening disorder that involves acute encephalopathy and fatty changes of the liver

Question 2

____ and Reye syndrome have similar manifestations and are both sometimes preceded by ____ infections. Testing is necessary to differentiate between the two

Answer 2

Meningitis; viral

Question 3

Reye syndrome primarily affects the liver and brain, causing what?

Answer 3

Liver dysfunction

Cerebral edema

Question 4

What is peak incidence of Reye?

Answer 4

When influenza is most common–Jan, Feb, and March

Question 5

What other disorders is Reye mistaken for?

Answer 5

• Encephalitis
• Meningitis
• Poisoning
• SIDS
• Diabetes
• Psychiatric illness

Question 6

There is potential associated between between using _____ products for treating fevers caused by viral infections and the development of Reye Syndrome

Answer 6

Aspirin

Question 7

Reyes syndrome typically follows a ____ infection such as flu, gastroenteritis, varicella

Answer 7

Viral infection

Question 8

How does Reye syndrome present?

Answer 8

In clinical stages based on the severity of liver and neurologic findings

Question 9

What are some characteristics of Reye syndrome?

Answer 9

• Lethargy
• Irritability
• Combativeness
• Confusion
• Delirium
• Profuse vomiting
• Convulsions
• LOC

Question 10

If client has Reye, what lab tests will be done and what will tests look like?

Answer 10

Elevated liver enzymes (ALT and AST)
Elevated serum ammonia
Altered serum electrolytes
Coagulation times may be extended

Question 11

What is the diagnostic procedure for Reye?

Answer 11

Liver biopsy

Question 12

A liver biopsy consists of taking a piece of liver tissue via a large bore needle, and sending this tissue to the pathology department. Care should be taken to ensure that the _____ are WNL prior to procedure

Answer 12

Clotting studies are WNL

Question 13

What nutritional status is needed prior to liver biopsy?

Answer 13

NPO

Question 14

What is monitored post procedure of liver biopsy?

Answer 14

Hemorrhage

Assess VS

Question 15

Should a lumbar puncture be done?

Answer 15

Yes, to rule out meningitis

Question 16

Maintain ____ while preventing _____

Answer 16

Maintain hydration while preventing cerebral edema

Question 17

How should client be positioned?

Answer 17

Maintain head in a midline neutral position

HOB elevated 30degree

Question 18

Is it okay to do extreme flexion, extension, or rotation exercises with the client with Reye?

Answer 18

No, avoid this!

Question 19

What should be monitored and prevented?

Answer 19

Monitor coagulation and prevent hemorrhage

Question 20

Provide private time for the family to be with the client if _____

Answer 20

Death is imminent

Question 21

Why would a diuretic be prescribed to pt. with Reye? What diuretic would be given?

Answer 21

To decrease cerebral swelling; osmotic (mannitol)

Question 22

What Vit. may be given and why?

Answer 22

Vit. K–improves synthesis of blood clotting factors in the liver

Question 23

What injection route is preferred for Vit K administration?

Answer 23

SQ

Question 24

Care after discharge: Teach parents to avoid giving salicylate to children and to read labels of OTC drugs to make sure salicylate aren’t in them. What are salicylate?

Answer 24

ASPIRIN

Question 25

After Reye’s do clients regain liver function? What about the neurological status?

Answer 25

Yes, regain liver function

May have neurological deficits

Question 26

What are complications of Reye?

Answer 26

Neurologic sequalea

Death

Question 27

A nurse is caring for a school age client with possibly has Reye syndrome. Which of the following is a risk factor for developing Reyes?

A. Recent history of infectious cystitis caused by candid
B. Recent history of bacterial otitis media
C. Recent episode of gastroenteritis
D. Recent episode of Ham. influ meningitis

Answer 27

C