Ch. 22: Respiratory System part 2 Flashcards

1
Q

Pulmonary ventilation (breathing) consist of two phases:

A

Inspiration( breathing in)

Expiration (breathing out)

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2
Q

List the 3 Pressures

A
Atmospheric pressure 760 mmhg
Intrapulmonary pressure (alveoli, equalizes with atm
Intrapleural pressure( pleural cavity, always negative)
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3
Q

Intrapleural cavity is always negative due to

A

lungs natural tendency to recoil

surface tension of alveolar fluid

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4
Q

Atelectasis ( lung collapse) occurs due to

A

Plugged bronchioles - collapse of alveoli
Wound that admits air into pleural cavity (pneumothorax)
Lack of surfactant

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5
Q

__________, Pressure is inversely proportional to Volume, P increase, V decrease

A

Boyle’s law

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6
Q

Inhalation: effects on diaphragm and intercoastal muscles and pressure

A

Pressure: decreases Volume: increases
Diaphragm: contracts Intercoastal muscles: contracts

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7
Q

During inhalation the pressure in the lungs are ____ than the atmospheric pressure

A

lower

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8
Q

The 3 physical factors influencing breathing are

A

Lung compliance, air resistance and alveolar surface tension

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9
Q

_______ is the major nonelastic source of resistance to gas flow

A

Friction

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10
Q

The relationship between flow (F), pressure (P), and resistance (R) is:

A

F= P/R
Change of pressure and Resistance
Gas flow inversely with resistance

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11
Q

Factors that decrease air resistance are:

A

Epinephrine and Antihistamines dilates bronchioles and reduces air resistance

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12
Q

Function of surfactant:

A

Reduces surface tension of alveolar fluid and discourages alveolar collapse

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13
Q

Define lung compliance

A

measure of the change in lung volume that occurs with a change in transpulmonary pressure.

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14
Q

Lung compliance is diminished by:

A

Nonelastic scar tissue (fibrosis)
Reduced production of surfactant
Decreased flexibility of the thoracic cage

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15
Q

___________, pulmonary gas exchange, capillary – alveoli

A

External respiration

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16
Q

three factors that influence external respiration

A

thickness and surface area of the respiratory membrane
partial pressure gradients and gas solubilities
ventilation( amount of gas reaching the alveoli) and perfusion ( blood flow in pulmonary)

17
Q

_________, normal breathing

A

tidal volume

18
Q

_______, maximum air you can inhale

A

inspiratory reserve volume

19
Q

__________, forcefully exhale out

A

expiratory reserve volume

20
Q

____________, air remaining in the lungs

A

Residual volume

21
Q

_________, inspired air fills the conducting respiratory passageways and never contributes to gas exchange in the alveoli

A

DEAD SPACE

22
Q

___________ involves capillary gas exchange in body tissues

A

Internal respiration

23
Q

Oxygen transport is carried in two ways

A

Bound to hemoglobin (98.5%)

Dissolved in Plasma (1.5%)

24
Q

Each hemoglobin molecules can bind to _ oxygen molecules

25
When 1-3 oxygen molecules are bound to a hemoglobin molecule, they refer as
partial saturated
26
When 4 oxygen molecules bound to hemoglobin molecule, they refer as
fully saturated
27
The rate at which Hb reversibly binds or releases O2 is regulated by
P02 and Pco2 temperature blood pH
28
Increases in temperature, H+, Pco2, and BPG lead to
Enhance O2 unloading
29
Inadequate O2 delivery to tissues
Hypoxia
30
``` Abnormal or too little Hb Blocked circulation Metabolic poisons Pulmonary disease Carbon monoxide ```
Anemic Ischemic (stagnant) Histotoxic Hypoxemic
31
Carbon dioxide transport 3 ways:
Dissolved in plasma: 7-10% Chemically bound to hemoglobin: 20% As bicarbonate ions in plasma: 70%
32
___________, an enzyme that reversibly catalyzes the conversion of carbon dioxide and water to carbonic acid
carbonic anhydrase
33
__________ and _____ are the main controllers of the regulation of breathing
medulla oblongata, and pons
34
___________, sensors responding to the changing levels of co2, o2 and h+ in arterial blood
chemoreceptors
35
______ is the most potent and most closely controlled, as well as the most powerful respiratory stimulant
CO2
36
An adaptive response to high altitudes
Acclimatization
37
___________, distinguished by destruction of alveolar walls, and permanent enlargement of the alveoli
emphysema
38
________, inhaled irritants lead to chronic production of excessive mucus, obstruct airways, impaling breathing and gas exchange
Chronis bronchitis
39
__________ , infectious disease caused by the bacterium Myobacterium tuberculosis
Tuberculosis