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Flashcards in Chapter 15 The adaptive Immune Response Deck (74)
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1

The scientist who received the first Nobel Prize in Medicine for his work on antibody therapy was


A. Koch.

B. von Behring.

C. Jenner.

D. Roux.

B. von Behring.

2

Proteins that react specifically with the chemical structures in the antigen that induced them are called


A. determinants.

B. antibodies.

C. proteases.

D. macroproteins.

B. antibodies.

3

Antibodies are made by


A. red blood cells.

B. macrophages.

C. B cells/plasma cells.

D. T cells.

C. B cells/plasma cells.

4

T cells primarily are responsible for


A. humoral immunity.

B. cell-mediated immunity.

C. anamnestic immunity.

D. producing haptens.

B. cell-mediated immunity.

5

Secondary lymphoid organs


A. are strategically located in the body.

B. facilitate interactions between cells.

C. are hematopoietic.

D. are the site of T cell maturation.

E. are strategically located in the body AND facilitate interactions between cells.

E. are strategically located in the body AND facilitate interactions between cells.

6

Epitopes or antigenic determinants


A. are parts of the antibody molecule.

B. are T cell receptors.

C. are a portion of antigen recognized by antibody.

D. may be approximately 10-25 amino acids in length.

E. are a portion of antigen recognized by antibody AND may be approximately 10-25 amino acids in length.

E. are a portion of antigen recognized by antibody AND may be approximately 10-25 amino acids in length.

7

The humoral immune response involves the manufacture and use of


A. antibodies.

B. T cells.

C. lymphokines.

D. antigens.

A. antibodies.

8

Which of the following is not typical of an antigen?


A. low molecular weight

B. protein

C. foreign

D. polysaccharide

E. low molecular weight AND protein

A. low molecular weight

9

Specific chemical groups on an antigen molecule to which the immune response is directed are


A. antigenic determinants.

B. an autoimmune response.

C. monomers.

D. allergens.

A. antigenic determinants.

10

Generally antigenic molecules usually have a molecular weight greater than


A. 10,000 Daltons.

B. 100,000 Daltons.

C. glucose.

D. most polysaccharides.


A. 10,000 Daltons.

11

Which of the following is/are secondary lymphoid organ(s)?


A. thymus

B. spleen

C. lymph nodes

D. bone marrow

E. spleen AND lymph nodes

E. spleen AND lymph nodes

12

A term synonymous with antibody is


A. antigen.

B. epitope.

C. determinant.

D. immunoglobulin.

D. immunoglobulin.

13

Which of the following do not induce a strong immune response?


A. lipids

B. proteins

C. polysaccharides

D. nucleic acids

E. lipids AND nucleic acids

E. lipids AND nucleic acids

14

There are ______ classes of antibody.


A. 1

B. 3

C. 5

D. 7

C. 5

15

Which of the following antibodies is a pentamer?


A. IgA

B. IgD

C. IgM

D. IgE

C. IgM

MASSIVE

16

The chains of an antibody molecule are bonded to one another by


A. disulfide bonds.

B. hydrogen bonds.

C. ionic bonds.

D. oxygen bonds.

A. disulfide bonds.

17

Which of the following antibodies is a dimer?


A. IgA

B. IgD

C. IgM

D. IgE

A. IgA

A plus you are a DIME

18

The immunoglobulin monomer consists of


A. 4 large chains.

B. 2 heavy and 2 light chains.

C. 5 light chains.

D. 3 heavy and 3 light chains.

B. 2 heavy and 2 light chains.

19

Which class of antibody accounts for the bulk of the circulating antibody?


A. IgA

B. IgD

C. IgG

D. IgE

C. IgG

Good Grief there are a lot

20

The characteristic function and properties of each class of antibody is determined by the


A. variable region on the light chain.

B. epitope.

C. constant region on the light chain.

D. constant region on the heavy chain.

E. variable region on the heavy chain.

D. constant region on the heavy chain.

21

An IgG molecule has two


A. heavy chains.

B. light chains.

C. antibody binding sites.

D. antigen binding sites.

E. heavy chains, light chains AND antigen binding sites.

E. heavy chains, light chains AND antigen binding sites.

22

The variable region of an antibody occurs


A. only on the heavy chains.

B. only on the light chains.

C. on one of the light chains.

D. on all 4 chains.

D. on all 4 chains.

23

Each class of antibody is specifically defined by its


A. amino acid sequence of the constant region of the heavy chain.

B. amino acid sequence of the variable region of the light chain.

C. ability to cross the placenta.

D. disulfide bonds.

A. amino acid sequence of the constant region of the heavy chain.

24

Antigens interact with antibodies at


A. the outer end of each arm of the Y.

B. the junction of heavy and light chains.

C. different regions depending on the class of antibody.

D. the bottom stem of the heavy chain of the Y.

A. the outer end of each arm of the Y.

25

Ag-Ab binding may result in


A. neutralization.

B. immobilization.

C. agglutination.

D. opsonization.

E. All of the choices are correct.

E. All of the choices are correct.

26

The Fc region on IgG


A. interacts with complement.

B. attaches to receptors on interleukin-1.

C. reacts with and coats the antigen.

D. contains a variable region.

E. interacts with complement AND attaches to receptors on interleukin-1.

A. interacts with complement.

27

How long after initiation of a primary response do significant amounts of antibody appear in the blood?


A. one day

B. 10-14 days

C. 4 weeks

D. 6 months

B. 10-14 days

28

The only class of antibody that can cross the placenta is


A. IgA.

B. IgD.

C. IgG.

D. IgE.

C. IgG.

GOO GOO gaa gaa

29

Which is the first antibody class made during the primary response to an antigen?


A. IgA

B. IgM

C. IgG

D. IgE

B. IgM

30

Which of the following is the most abundant immunological class produced?


A. IgA

B. IgD

C. IgG

D. IgE

A. IgA

most produced but it leaves in mucus, tears, saliva etc.

AWAY