Flashcards in Chapter 17 Deck (29):
Defenses against any pathogen
Induced resistance to a specific pathogen
How to get adaptive immunity
Also called adaptive immunity
Bodys third line of defence
Specific immunity due to two types of lyphocytes
-B lymphocytes (B cells)
-T lymphocytes (T cells)
A substance that causes the body to produce specific antibodies or sensitized T cells.
Examples of antigens (5)
Specific region of Ag that combines with products of the I.S. Binding sites.
Is a globular protein made in response to a specific antigen.
Antibody (ab) or Immunoglobulin (Ig)
Are chemical messengers released primarily by helper T cells.
Antigen presenting cells
What happens if you don't have cytokines?
How does the immune system recognize itself/nonself?
Markers called Major Histocompatability Complex cells. Monitor the expression of MHC class 1 molecules. If the cell has class 1 that is empty it is left alone. I it presents with a virus it is killed on contact.
Cells of the specific imune system
Stay in bone marrow. Mature in bone marrow and acquire receptors (specific shape). Programed to make specific antibody. Secrete antibodies in fluids. Involved in humoral immunity.
Acquire receptors (Specific shape) in thymus. Cellular (cell to cell interaction). Antigen must be presented to them.
B Cell receptors can recognize ag in its natural state. For example: ...............
Before these agents enter the cells.
-Bacteria in blood.
-Viruses in blood.
-Toxins in the blood.
When a B cell encounters its triggering antigen it gives rise to what?
Shape of Antibody
2 heavy chains
2 Light chains
Y arms vary greatly (To accommodate millions of possibilities)
Functions of antibodies?
Agglutination (Group together)
Activation of complement
Antibody dependent cell mediated cytotoxicity
Most abundant antibody (in blood)
Which antibody crosses the placenta?
Which antibody is found on secretions
Which antibody is largest?
Triggers memory cells
T dependent antibodies