Chapter 3: Both Inflammations Flashcards

1
Q

According to what factors is Inflammation classified into? (2 points)

A

Lesion duration

Histologic appearances

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2
Q

What are the 3 types of Inflammation?

A

Acute
Chronic
Subacute

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3
Q

Define subacute inflammation

A

Categorized between acute and chronic Inflammation types

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4
Q

Which 2 types of Inflammation are the histologic appearances?

A

Acute

Chronic

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5
Q

What are the Systemic effects/manifestations of Inflammation? (8 points)

A

Fever
Weight loss
4 Responses

Leukocytosis
Or
Leukopenia

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6
Q

What are these 4 responses?

A

Endocrinal
Behavioral
Metabolic
Autonomic

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7
Q

What is the most important systemic effect/ manifestation of Inflammation?

A

Fever

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8
Q

What coordinate the Fever? (2 points)

A

Hypothalamus

Cytokines

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9
Q

What coordinates the Hypothalamus?

A

Cytokines

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10
Q

What are the types of Cytokines that coordinate the Fever?

A

IL-1
IL-6
TNF-α

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11
Q

Which cells release the Cytokines?

A

Macrophages

Others

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12
Q

What do the Endocranial and Metabolic responses include? (6 points)

A

4 Proteins
Glucocorticoids
Vasopressin

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13
Q

What are the 4 proteins included in the Endocranial and Metabolic responses?

A

C-reactive
Serum Amyloid A
Complement
Coagulation

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14
Q

What are these proteins secreted from?

A

Liver

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15
Q

Describe the secretion of Glucocorticoids

A

Increased

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16
Q

Describe the secretion of Vasopressin

A

Decreased

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17
Q

What do the Autonomic responses include?

4 points

A

Blood flow redirection
Pulse rate
Blood pressure
Sweating

18
Q

What is the blood flow directed from?

19
Q

What is the blood flow directed to?

A

Deep Vascular bed

20
Q

Describe the pulse rate

21
Q

Describe the blood pressure

22
Q

Describe the sweating

23
Q

What do the Behavioral responses include?

4 points

A

Rigor
Chills
Anorexia
Malaise

24
Q

What is a common feature of Inflammation?

A

Leukocytosis

25
What are the examples that cause Leukocytosis? (4 points)
2 Infections Parasitic infestations Allergic reactions
26
What are the 2 examples of infections that cause Leukocytosis?
Bacterial | Some Viral
27
Among all the causes, which cause is Leukocytosis especially common in?
Bacterial Infection
28
Which cells do most Bacterial infections induce?
Neutrophils
29
What are examples of some Viral infections that cause Leukocytosis? (2 points)
Infectious Mononucleosis | Mumps
30
What are examples of Parasitic infestations and Allergic reactions that cause Leukocytosis? (2 points)
Bronchial Asthma | Hay Fever
31
Which cells are induced by Parasitic infestations?
Eosinophilia
32
What unit is used to count the Leukocytosis?
cells/mm3
33
What is the Leukocytosis usual range number?
15K-20K
34
What is Leukopenia a feature of?
Typhoid Fever | Some Parasitic Infections
35
The action of what causes Weight loss? (2 points)
IL-1 | TNF-α
36
What is the action of IL-1 and TNF-α?
Increase Catabolism
37
What do IL-1 and TNF-α increase the Catabolism of? (3 points)
Muscles Tissue Liver
38
Which muscles' catabolism increases by IL-1 and TNF-α?
Skeletal
39
Which tissue's catabolism increases by IL-1 and TNF-α?
Adipose
40
What does the increased Catabolism of these examples cause?
Negative Nitrogen Balance