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Pharm Unit 2 MJC > Cholinergic Receptor Inhibitors Class/mechanism > Flashcards

Cholinergic Receptor Inhibitors Class/mechanism Flashcards

1
Q

Atropine

A

Tertiary amine antimuscarinic

blocks muscarinic receptors

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2
Q

scopolamine (transderm-scop)

A

Tertiary amine antimuscarinic

blocks muscarinic receptors

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3
Q

Dicyclomine (Bentyl)

A

Tertiary amine antimuscarinic

blocks muscarinic receptors

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4
Q

Tropicamide (mydriacyl)

A

Tertiary amine antimuscarinic

blocks muscarinic receptors

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5
Q

Tolterodine (detrol)

A

Tertiary amine antimuscarinic

blocks muscarinic receptors

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6
Q

Benztropine (Cogentin)

A

Tertiary amine antimuscarinic

blocks muscarinic receptors

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7
Q

Ipratropium (Atrovent)

A

Quaternary amine antimuscarinic

blocks muscarinic receptors

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8
Q

Tiotropium (spiriva)

A

Quaternary amine antimuscarinic

blocks muscarinic receptors

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9
Q

Hexamethonium (Methium)

A

Ganglionic blocker

blocks ganglionic Nn/N2 receptor and sympathetic tone

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10
Q

Mecamylamine

A 
ganglionic blocker (Crosses BBB)
blocks ganglionic Nn/N2 receptor and sympathetic tone
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11
Q

Succinylcholine (Anectine)

A

Depolarizing blocker

overstimulation of nicotinic receptor, leading to desensitization of muscle unit to further ACh stimulation

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12
Q

Tubocurarine (Curare)

A

Nondepolarizing blocker

blocks nicotinic Nm/N1 receptor

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13
Q

Mivacurium (Mivacron)

A

Nondepolarizing blocker

blocks nicotinic Nm/N1 receptor

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14
Q

Botulinum toxin A (Botox)

A

Local paralytic

Blocks vesicle fusion and ACh release on presynaptic terminal by degrading SNAP-25

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Pharm Unit 2 MJC (25 decks)

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