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Jason's Renal Block > Chronic & Acute Renal Failure > Flashcards

Flashcards in Chronic & Acute Renal Failure Deck (59)
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1

Do you need ARF to get CRF?

Nope

2

if you have CRF does that mean you had to have ARF?

Nope

3

Renal failure is defined as failure of what?

filtration

4

ARF reversible?

yes the sooner you treat it the better the outcome

5

definition of renal failure is how much urine flow per day?

less than 500ml/day

6

CRF timeline? reversible?

develops over 6 months-years
irreversible

7

What is normal GFR /min? /day?

125ml/min
180ml/day

8

GFR at 65? at 80?

65: 100ml/min 144L/day
80: 75ml/min 108L/day

9

What is considered significant CRF ____ml/min?

<72L per day

10

loss of GFR is coupled with loss of?

tubular reabsorption/secretion

11

When do you get endocrine impairment with renal failure?

more so CRF

12

3 main endocrine impairment with renal failure?

RAS: +++vasocontriction
impaired vitamin D activation
decreased erythropoeitin - anaemia

13

plasma urea for GFR assessment?

NOPE. crap

14

what is normal creatinine levels?

50-120uM/L

15

equation for creatinine clearance?

UV/P = GFR

16

Normal hydrostatic pressure in glomerulus is?

55mmHg

17

when do you no longer filter anything in glomerulus?

<40-45mmHg

18

ARF: What's more common? oliguria? Anuria?

oliguria

19

ARF: GFR falls how?

acutely hours/days

20

3 areas of acute renal failure?

pre-renal
renal
post-renal

21

what is ATN?

acute tubular necrosis

22

in pre-renal ARF: what would systemic and Glomerulous pressures be less than?

systemic: <45mmHG

23

causes of pre-renal ARF? 5 big ones

Shock
Sepsis
Haemolysis
rhabdomyolysis
nephrotoxic drugs

24

3 big causes of renal/intrinsic ARF?

glomerular disease
interstitial nephritis
tubular damage

25

what can cause glomerular disease?

IgA immune complexes post group A strep infections

26

interstitial nephritis often related to?

drugs

27

3 Toxins that can cause tubular damage in ARF?

antibiotics
contrast media
myo/haemoglobin

28

2 ischemic events that cause tubular damage in ARF? which one is most common?

ATN (most common)
vascular obstruction

29

how does ATN cause death?

Acidosis, increase in K+ levels: arrythmias

30

what is a post-renal cause of ARF?

outlet obstruction
stones, clots, tumours