Flashcards in Renal Histology Deck (22)
What do arcuate vessels do?
between cortex/medulla and form interlobular/interlobar vessels
2 kinds of nephrons and percentage?
What is the hollow space between capillaries and capsule in the nephron?
What are mesangial cells?
type of pericyte and smooth muscle cells of the glomerulus
What are podocytes?
specialised epithelial cells that form final level of filtration, surrounds the fenestrated endothelium
what are slit membranes?
3-5 nm pores between podocyte foot processes
what does the thick basal lamina plus slit membrane provide?
What's overall point of the renal tubules to produce?
hyperosmotic urea-rich fluid
Proximal tubule has what kind of epithelium? describe.
thick: ion pumps and mitochondria
folded basolateral membrane
describe the thin walled part of the tubules histologically
simple squamous cells
describe the features of distal tubule histologically? 4 big things.
thick: lots of mitochondria and ion pumps
purpose of macula densa? where is it?
distal tubule that passes between afferent and efferent arteriole
Chemoreceptor function/monitor filtrate
what and where are the juxtaglomerular cells and what do they release? how are they signaled?
on afferent and efferent arteriole
release renin, signalled from paracrine macula densa
describe collecting duct histologically 3 big ones
simple cuboidal becoming more columnar
impermeable to water unless ADH or vasopressin is present.
what happens to efferent arteriole after the glomerulus?
crucial for urine concentration
describe the ureter histologically
simple muscular tube
ureter peristalsis is regulated by what kind of nerves?
describe urinary bladder histologically
smooth muscle during micturation
transitional epithelium: describe
non-permeable (very tight junctions)
what do the membrane plaques in the outer players of bladder transitional epithelium do?
stretch during distension
describe urethra histologically
first: transitional epithelium
then stratified squamous