Renal Histology Flashcards Preview

Jason's Renal Block > Renal Histology > Flashcards

Flashcards in Renal Histology Deck (22):
1

What do arcuate vessels do?

between cortex/medulla and form interlobular/interlobar vessels

2

2 kinds of nephrons and percentage?

cortical (85%)
juxta-medullary (15%)

3

What is the hollow space between capillaries and capsule in the nephron?

Bowman's space

4

What are mesangial cells?

type of pericyte and smooth muscle cells of the glomerulus

5

What are podocytes?

specialised epithelial cells that form final level of filtration, surrounds the fenestrated endothelium

6

what are slit membranes?

3-5 nm pores between podocyte foot processes

7

what does the thick basal lamina plus slit membrane provide?

filtration barrier

8

What's overall point of the renal tubules to produce?

hyperosmotic urea-rich fluid

9

Proximal tubule has what kind of epithelium? describe.

simpel cuboidal
microvilli
thick: ion pumps and mitochondria
folded basolateral membrane

10

describe the thin walled part of the tubules histologically

simple squamous cells

11

describe the features of distal tubule histologically? 4 big things.

simple cuboidal
larger lumen
no microvilli
thick: lots of mitochondria and ion pumps

12

purpose of macula densa? where is it?

distal tubule that passes between afferent and efferent arteriole
Chemoreceptor function/monitor filtrate

13

what and where are the juxtaglomerular cells and what do they release? how are they signaled?

on afferent and efferent arteriole
release renin, signalled from paracrine macula densa

14

describe collecting duct histologically 3 big ones

simple cuboidal becoming more columnar
large lumen
impermeable to water unless ADH or vasopressin is present.

15

what happens to efferent arteriole after the glomerulus?

vasa recta
crucial for urine concentration

16

describe the ureter histologically

simple muscular tube
transitional epithelium

17

ureter peristalsis is regulated by what kind of nerves?

autonomic nerves

18

describe urinary bladder histologically

transitional epithelium
smooth muscle during micturation
controlled autonomically/voluntarily

19

transitional epithelium: describe

multipayered
non-permeable (very tight junctions)
membrane plaques

20

what do the membrane plaques in the outer players of bladder transitional epithelium do?

stretch during distension

21

describe urethra histologically

first: transitional epithelium
then stratified squamous

22

what is the external urethral sphincter surrounded by? how controlled?

striated muscle
somatic nerves