Chronic Lung Infections Flashcards Preview

Year 1 - Respiratory (DP) > Chronic Lung Infections > Flashcards

Flashcards in Chronic Lung Infections Deck (12):
0

How does chronic lung sepsis present?

Weight loss
Persistent sputum
Chest pain
Increased SoB
Shadow on CXR

1

Risk factors for developing chronic lung infection

Immunodeficiency
Immunosuppressive
Damaged mucosa/cilia
Repeated insults

2

What immunodeficiencies can lead to chronic lung infections?

Ig deficiencies
- IgA deficiency is common
- Hypogammaglobulinaemia is rare
- Common Variable Immunodeficiency is the commonest
- Specific Polysaccharide Antibody Deficiency

Hyposlenism
Malignancy
HIV

3

What do Kartagener syndrome and Youngs syndrome cause?

Abnormal cilia and hence defective defence

4

What can result in recurrent aspiration?

NG feeding
Poor swallow (MND)
Pharyngeal pouch

5

What forms of chronic infection are there?

Intrapulmonary abscess
Empyema
Chronic bronchial sepsis
Bronchiectasis
CF

6

What infections typically precedes an Intrapulmonary abscess?

Staph aureus -> cavitating pneumonia -> abscess
Other
- Strep
- E. coli
- Gram negatives
- Aspergillus

7

What is empyema?

Pus in the pleural space

8

How do we diagnose chronic pulmonary infections?

Clinical suspicion
- Slow to resolve pneumonia
CXR
- Persisting effusion
- D sign
USS
CT

9

What is the broad treatment of infection?

Amoxicillin + Metronidazole + Gentamicin

10

What is bronchiectasis?

Localised, irreversible bronchial tree dilation

11

How can exacerbations of infections be reduced?

Clarithromycin (250mg OD)
Azithromycin (250mg 3 times weekly)