Respiratory Tract Infection Flashcards
What antibiotics are used to treat an infective exacerbation of COPD?
Doxycycline or amoxicillin
What are the clinical features of acute bronchitis?
Productive cough
Fever
Normal CXR
Transient wheeze
What drugs can be used to treat influenza?
Zanamivir
Oseltamivir
What bacteria cause TB?
Mycobacterium tuberculosis
M. bovis
M. africanum
What is the primary test for TB?
PCR
What stain is used for TB culture?
ZN Acid-Fast bacilli
What is IGRA testing?
Interferon Gamma Release Assay testing If positive - current TB - previously treated TB - latent TB
How is TB treated?
Rifampicin, Isoniazid, Pyrazinamide and Ethambutol for initial 2 months
THEN
Rifampicin and Isoniazid for a further 4 months
How is latent TB treated?
Prior to immunosuppressive therapy (infliximab, etanercept, adalimumab, rituximab)
3 months of Isoniazid and Rifampicin
What drugs is MDR-TB resistant to?
Isoniazid
Rifampicin
What drugs is XDR-TB resistant to?
Isoniazid
Rifampicin
Fluoroquinolones
Injectables
What is the causative organism in acute epiglottitis?
Haemophilia influenzae
How does acute epiglottitis present?
Severe croup
Resp obstruction
Treatment of Haemophilus influenzae
Ceftriaxone
What are the first and second line treatments in infective exacerbations of COPD?
1st line - Amoxicillin (500mg TID for 5 days)
2nd line - Doxycycline (200mg on day 1 then 100mg OD for 4 days)
