Circulatory Flashcards

(44 cards)

1
Q

What is perfusion?

A

flow of blood through tissue

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2
Q

What is Ischemia?

A

inadequate blood flow. Waste builds up

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3
Q

what is Hypoxia?

A

reduced supply of oxygen in the blood

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4
Q

Does exchange happen in arterioles?

A

No

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5
Q

What is angiogenesis?

A

Formation of new blood vessels by proliferation of epithelial cells

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6
Q

What prevents backflow of blood?

A

Venous Valves

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7
Q

What happens during diastole?

A

ventricles relax, blood flows in from atria. Atria contract

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8
Q

What happens during systole?

A

ventricles contract, AV valves shut

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9
Q

Which is longer Diastole or Systole?

A

Diastole

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10
Q

What is stroke volume?

A

amount of blood pumped with each systole

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11
Q

what is cardiac output?

A

total amount of blood pumped per minute

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12
Q

What does cardiac output equal?

A

stroke volume x heart rate

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13
Q

Is the cardiac output the same in the left and right ventricles?

A

Yes. So backup does not occur

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14
Q

What are ways to increase cardiac output?

A

increase venous return and arterioles dilating

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15
Q

What are fast sodium channels?

A

Open first in response to depolarization to allow sodium to enter

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16
Q

What are slow calcium channels?

A

Open in response to threshold voltage and allow calcium down its gradient. Stay open longer creating plateau phase

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17
Q

What feature maximizes calcium entry into cardiac muscle cells once an action potential arrives?

A

T-Tubules

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18
Q

In the heart what releases calcium?

A

Sarcoplasmic reticulum

19
Q

Which have longer refractory periods neurons or cardiac muscle?

A

Cardiac muscle

20
Q

What are the three phases of the SA node?

A

Phase 0, Phase 3, Phase 4

21
Q

Why does the SA node have unstable resting potential?

A

Due to phase 4 and sodium leak channels allowing sodium in to push for threshold

22
Q

What happens at phase 0?

A

VG Calcium channels open

23
Q

What happens at phase 3?

A

Repolarization. Closure of Calcium channels and opening of potassium channels.

24
Q

Which node sets the rate of heart contraction?

25
What happens during phase 1?
Sodium channels inactivate, Potassium Channels open, Potassium efflux
26
What happens during phase 2?
Plateau. Calcium channels open, Calcium influx, Potassium efflux
27
What is the driving force in blood flow?
Difference in pressure from arteries to veins
28
What does Ohm's Law tell about blood flow?
In order to change blood flow, you must change pressure or resistance
29
How can pressure be varied?
Changing force or rate of contraction
30
What is the determinant of resistance in vessels?
Precapillary sphincters
31
What causes an increase in resistance?
Contraction of smooth muscle by sympathetic nervous system. Vasoconstriction
32
What hormone provides basal level of pressure?
Norepinephrine
33
What are platelets?
Form plug to fix damage to blood cells
34
What is hemostasis?
body's mechanism of preventing bleeding
35
What is fibrin?
protein forming mesh that holds platelet plug together
36
What is fibrinogen?
converted into fibrin by thrombin when bleeding occurs
37
When is oxygen not favored by hemoglobin?
decreased pH, increased PCO2, increased temperature
38
What is the site of exchange between blood and tissues?
capillaries
39
What causes water to flow out of capillaries?
Hydrostatic Gauge Pressure and differences in osmolarity
40
What substance freely passes through capillaries?
Salts
41
What cells are able to squeeze through capillaries?
Macrophages and neutrophils
42
What gives plasma high osmolarity?
Albumin
43
What is oncotic pressure?
Osmotic Pressure provided by plasma protein
44
Where is hydrostatic pressure the lowest?
Near the end of a capillary