Viruses Flashcards

1
Q

What do viruses need to survive?

A

A host

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2
Q

What kind of nucleic acid can a virus have?

A

DNA or RNA

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3
Q

What is a bacteriophage?

A

virus that infects bacteria

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4
Q

What are viruses that do not have envelopes called?

A

Naked viruses

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5
Q

What kind of organisms do phages infect?

A

Hosts with cell walls

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6
Q

What is an early gene?

A

Expressed immediately after infection and includes any special enzymes required to express viral genes

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7
Q

What about a virus determines the specificity of the host it can infect?

A

the surface of the virus

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8
Q

How is a virus taken into a cell?

A

Receptor Mediated endocytosis or fusion

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9
Q

Why might antibodies have a hard time accessing a viral capsid?

A

due to the envelope as it contains host membrane components

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10
Q

What is the outcome of the lytic cycle?

A

The cell lyses

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11
Q

The early gene in the lytic cycle produces which enzyme?

A

hydrolase

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12
Q

Which enzyme is transcribed from the lytic cycle late?

A

lysozyme

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13
Q

What is the phage genome incorporated into the bacterial genome known as in lysogenic cycle?

A

prophage

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14
Q

What is the host called during the lysogenic cycle?

A

lysogen

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15
Q

What makes the prophage silent?

A

phage encoded repressors that bind to phage promoters

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16
Q

What is the outcome of the lysogenic cycle?

A

prophage activates and excises itself from the host genome. Then enters the lytic cycle

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17
Q

What is an advantage to the lytic cycle?

A

useful for rapidly increasing numbers but host cells are destroyed

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18
Q

What is a consequence of the lysogenic cycle?

A

By excising, it may take part of the host genome with it

19
Q

What is transduction?

A

process of host genome being packaged with viral genome and can spread to new host. There will be a presence of new DNA

20
Q

Are animal viruses phages?

21
Q

how do animal virus enter animal cells?

A

endocytosis

22
Q

What is the productive cycle of animal viruses?

A

enveloped virus exits host by budding through but does not destroy cell. The envelope becomes coated with membrane

23
Q

What is a prophage called in animal cells?

24
Q

Is there a lysogenic cycle in animal cells?

25
Do positive RNA viruses need to encode RNA dependent RNA Pol?
yes
26
What kind of RNA genome does positive RNA viruses have?
single stranded RNA genome
27
When does translation occur for positive RNA viruses?
upon entrance into cell and acts directly as mRNA. The genome is effective
28
Negative RNA viruses must carry what polymerase?
RNA dependent RNA Pol and encode it
29
What is negative RNA a template for?
negative mRNA [roduction
30
If host ribosomes translate negative RNA what happens?
useless polypeptides are made
31
Where is the RNA dependent RNA Pol carried in the virus?
The capsid
32
What results from using negative RNA strand for template of RNA dependent RNA Pol?
Positive RNA strand
33
Retroviruses encode what enzyme?
Reverse transcriptase
34
What kind of RNA viruses are retroviruses?
Positive RNA viruses that undergo lysogeny.
35
What does Reverse transcriptase use?
Use RNA to make DNA
36
What are the three retroviral genes?
gag, pol, env
37
What does the gene gag encode?
capsid proteins
38
What does the gene pol encode?
Reverse transcriptase
39
What does the gene env encode?
viral envelope proteins
40
What are subviral particles?
infectious agents smaller and more simple than a virus
41
What are prions?
Subviral self replicating proteins that are shape based. It is a misfolded version of a protein that all ready exists
42
What makes prions hard to destroy?
Misfolded proteins are resistant to degradation by chemicals or heat
43
What makes prion diagnosis difficult?
long incubation periods
44
What are viroids?
short piece of circular single stranded RNA with excessive self complementarity that does not code for proteins