Circulatory System Flashcards

1
Q

Blood structure

A

plasma- fluid component (55%) and carries ions, nutrients, and gases
buffy coat- 1% and contains white blood cells and platelets
red blood cells- 45%, hematocrit. carries gases like CO2 and O2

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2
Q

Platelets

A

Cell fragments and are essential for coagulation (blood clotting) and are derived from megakaryocytes

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3
Q

Coagulation cascade

A

Clotting factors have Prothrombin be converted to Thromin which is then converted to Fibrinogen and the Fibrin

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4
Q

Erythrocytes and their glycoproteins

A

This is what ABO blood typing is based off of

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5
Q

Rh factor

A

+= have the factor

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6
Q

Erythropoietin

A

it is released from the kidney and its role is stimulation of red blood cell development

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7
Q

The two parts of the cardiovascular system

A

systemic circulation

pulmonary circulation

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8
Q

systemic

A

takes oxygen rich blood to tissues and the returns the now oxygen depleted blood to the heart

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9
Q

Pulmonary circulation

A

circulatory system through the lungs

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10
Q

Arteries function

A

carry blood away from the heart
arteries of systemic circulation carry oxygenated blood to tissues, but the pulmonary artery carries de-oxygenated blood from the heart to the lungs. also, umbilical artery carries de-oxygenated blood from fetus to placenta to become oxygenated to return back to fetus

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11
Q

Artery anatomy

A

Have a thick muscular wall and are adaptable. branch off into arterioles and lead to capillaries

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12
Q

Veins

A

carry blood to heart. start off as venules and become larger. BP is low in veins

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13
Q

How is the gravity issue solved when returning blood to heart through veins?

A

A valve allows to go to heart, but prevents back flow. Also, skeletal muscle helps

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14
Q

The layers of blood vessels

A
Tunica externa 
Tunica media 
Tunica intima (thin layer of endothelial cells)
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15
Q

Atherosclerosis

A

Fatty plaque build up in arteries. can lead to heart attack if build up is in heart

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16
Q

Heart anatomy

A

right and left atria

right and left ventricle

17
Q

Valves in the heart

A

Tricuspid on right

Bicuspid on left

18
Q

What is the difference between systole and diastole?

A

contract, relax respectively

19
Q

Electrical system of the heart

A

SA node is right atrium with pacemakers. forces heart to contract when given an action potential. after, AV node helps transmit signals along with bundle of His and purkinje fibers

20
Q

Hemoglobin

A

4 subunits with a heme group (including ion) and this is what binds the oxygen.

21
Q

R state

A

high affinity for oxygen

22
Q

T state

A

low affinity for oxygen

23
Q

Shifts in disassociation curve

A
left: 
decre temp 
decre 2,3-BPG
incre pH
fetal HB

Right:
incre temp
incre 2,3-BPG
decre pH

24
Q

Myoglobin

A

one subunit and has a higher affinity for oxygen than HB

25
Q

When does the mother’s immune system attack the fetus?

A

when the mother is negative and the fetus as positive