Citroni Tutorial #3 Flashcards Preview

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Flashcards in Citroni Tutorial #3 Deck (25):
1

What is SIRS stand for?

systemic inflammatory response syndrome

2

what happens in SIRS?

fenetrations in the intravascular compartment get larger, too much Na+ in ECF

3

where does H20 go in the compartments?

EVERYWHERE (all 3)

4

What is the 3rd space?

ECF

5

what holds water in the ECF?

glycoprotein matrix

6

what holds water in the intracellular compartment?

Na/K+ pump

7

what does Na/K+ pump do to intracellular and ECF?

makes a concentration gradient

8

is ECF usually measured?

only in pathology, etc. ascites

9

what holds fluid in the intravascular compartment?

Albumin

10

conc. of K+ intracellular?

~140mmol/L

11

conc. of K+ intravascularly?

3.5-5mmol/L

12

conditions where you get hypervolaemia?

Heart and liver failure

13

what happens in isovolaemia?

increased H20, normal Na+

14

what conditions cause isovolaemia?

H20 intoxication

15

what can severe hyponatraemia cause?

cerebral oedema
seizures

16

2 causes of hypovolaemia?

thiazides
addisonian state

17

why do you not give 5% dextrose after surgery?

due to SAADH, would cause H20 toxicity

18

How to correct acute Hyponatraemia?

quickly up to symptom relief (no seizures around 115-120), then go slow up to 140

19

side effect of overcorrection of hypoNa+?

CPM
central pontine myelosis

20

how slow to correct chronic hypo-natraemia?

21

is normal saline normal? why?

Nope: 150mmol/L of Cl when physiological is (95-105)

22

Diabetes insipidus urine output can be?

>200-1000ml/hr

23

how does ADH work?

aquaporins translocate to collecting ducts, absorbs water

24

specific gravity of someone with D.I.?

25

what happens to urine and serum in SIADH?

concentrated urine
low serum osmolality