Flashcards in Citroni Tutorial #3 Deck (25):
1
What is SIRS stand for?
systemic inflammatory response syndrome
2
what happens in SIRS?
fenetrations in the intravascular compartment get larger, too much Na+ in ECF
3
where does H20 go in the compartments?
EVERYWHERE (all 3)
4
What is the 3rd space?
ECF
5
what holds water in the ECF?
glycoprotein matrix
6
what holds water in the intracellular compartment?
Na/K+ pump
7
what does Na/K+ pump do to intracellular and ECF?
makes a concentration gradient
8
is ECF usually measured?
only in pathology, etc. ascites
9
what holds fluid in the intravascular compartment?
Albumin
10
conc. of K+ intracellular?
~140mmol/L
11
conc. of K+ intravascularly?
3.5-5mmol/L
12
conditions where you get hypervolaemia?
Heart and liver failure
13
what happens in isovolaemia?
increased H20, normal Na+
14
what conditions cause isovolaemia?
H20 intoxication
15
what can severe hyponatraemia cause?
cerebral oedema
seizures
16
2 causes of hypovolaemia?
thiazides
addisonian state
17
why do you not give 5% dextrose after surgery?
due to SAADH, would cause H20 toxicity
18
How to correct acute Hyponatraemia?
quickly up to symptom relief (no seizures around 115-120), then go slow up to 140
19
side effect of overcorrection of hypoNa+?
CPM
central pontine myelosis
20
how slow to correct chronic hypo-natraemia?
21
is normal saline normal? why?
Nope: 150mmol/L of Cl when physiological is (95-105)
22
Diabetes insipidus urine output can be?
>200-1000ml/hr
23
how does ADH work?
aquaporins translocate to collecting ducts, absorbs water
24
specific gravity of someone with D.I.?
25