Common Antibody keywords in Diseases Flashcards Preview

COMLEX 2 > Common Antibody keywords in Diseases > Flashcards

Flashcards in Common Antibody keywords in Diseases Deck (15):
1

anti-dsDNA, anti-Smith

"flea-bitten" appearance on the cortical surface of the kidney (SLE)

2

Anti-citrullinated peptide/protein antibodies (CCP)

Elevated in a patient with distal interphalangeal hyper flexion and proximal interphalangeal hyperextension (RA)

3

Anti-Scl 70/Antinuclear/Antitopoisomerase Abs

Decreased respiratory ventilation and diffusing capacity for carbon monoxide as well as occasional skin discoloration in the fingertips (scleroderma)

4

Anti-U1 ribonucleoprotein antibody

Causes myalgias, skin color variation with temperature change and hypergammaglobinemia (Mixed Connective Tissue Disease)

5

Anti-Ro/SSA antibody

Causes slow heart rate with intermittent cannon waves in the neck in a neonate (Neonatal Lupus)

6

ANA

SLE

7

Anti-Centromere

CREST

8

Anti-Histone

SLE (Drug induced)

9

Anti-Jo-1

Polymyositis & Dermatomyositis

10

Antimitochondrial Abs

Primary Biliary Cirrhosis (PBC)

11

Anti-smooth muscle Abs

Auto-immune Hepatitis

12

Anti-TSH-R

Graves' Disease

13

c-ANCA

Wegener's

14

p-ANCA

Microscopic Polyangiitis & Churg-Strauss

15

Anti-thyroglobulin, Anti-TPO Abs

Hashimoto's Thyroiditis (autoimmune hypothyroidism)