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Flashcards in Resp Deck (19):
1

Chronic COPD ABG

Respiratory
pH 7.30
pCO2 >40 (hypercapnea)
pO2 24 as this is chronic

2

Cold agglutinins

IgM Abs that agglutinate RBCs at 4C (39.2 F)
Seen with Mycoplasma pneumoniae (extracellular bacteria)

3

Tx. Atypical CAP d/t Mycoplasma pneumoniae

Erythromycin

4

Rocuronium and Sevoflurane can cause what adverse effect?

Malignant Hyperthermia

5

S&S of Theophylline toxicity

HypOtension, lethargy, confusion, A. Fib, seizures

Formerly used to reverse bronchospasm in asthma/COPD by inhibiting phosphodiesterase and releasing epinephrine from adrenal medulla

6

S&S of Massive Pulmonary Embolism (PE)

- HypOtension
- Acute RV failure --> neck vein distension (as blood backs up because RV can't push it to lungs) --> ↑ CVP
- ↑ Pulm. A. Pressure (d/t hypoxic vasoconstriction)
- Normal PCWP, SVR
- ↓ Cardiac Index (SV * HR / BSA)
- Right Bundle Branch Block

7

Mycobacterium tuberculosis category

Obligate aerobe

8

Pink puffers

Emphysema: purse lips, no cough, decreased breath sounds

9

Blue bloaters

Chronic bronchitis: cyanosis, cough, right-sided heart failure (Elevated end-diastolic right ventricular pressure: Systemic congestion - enlarged liver, ascites, jugular venous distention, dependent pitting edema; fatigue, liguria, nocturia, cyanosis, pleural effusion, anorexia and bleeding, unexplained weight gain)

10

Tx. for nosocomial pneumonia d/t pseudomonas

Piperacillin + Amikacin

11

Succinylcholine (depolarizing NM blocking drug)

MOA

Adverse SE

ACh receptor agonist causing sustained depolarization thus preventing mm. contraction

hypercalcemia, hyperkalmia, malignant hyperthermia

12

Pancuronium (non-depol NM blocking drug)

MOA

Reverse blockade with?

competitive antagonist of ACh

Reversal of blockade: Neostigmine, Edrophonium, Cholinesterase Inhibitors

13

DVT/PE Tx?

Heparin + Warfarin simultaneously for 5 days, until INR 2.0-3.0 then Warfarin only

14

Legionnaire's Disease keywords

Fever >103
Elderly males
Watery diarrhea
Mental status changes

15

Findings seen in Bronchiectasis?

CXR reveals:

Increased bronchovascular markings
Tram lines
Prominent bronchioles
Atalectasis
Honeycombing
Decreased FEV1/FVC

16

If a pt. has complicated pneumonia with no resolution even after ABX, get what diagnostic procedure done?

Bronchoscopy.

- can identify lung masses and collection of cultures

17

Aspergilloma

Dx?

Tx.?

"Fungal ball"
Cavitary lesion

Dx: Bronchoalveolar lavage

Tx: Voriconazole

18

Empiric ABX for Community Acquired Pneumonia?

Doxycycline for those younger than 60 y.o.

For 60+ y.o.: 3rd gen cephalosporins, Augmentin, Macrolides, and fluoroquinolones

19

TRALI

pathophys

fever, tachycardia, tachypnea, ↑ Peak airway pressure

- complement-mediated ↑ in pulmonary vascular permeability d/t transfusion