Derm Flashcards

(32 cards)

1
Q

Psoriasis keywords

A

Extensors
Onycholysis
Auspitz
Munro’s microabscess (Neutrophils in stratum corneum)

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2
Q

What is onycholysis and what disease process are you likely to see it in?

A

Separation of nail from nail bed (white area of nail plate getting bigger)

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3
Q

Erythema Multiforme description
Triggers
Complications
Diagnostic considerations

A

Erythematous Targetoid lesions on mucous membranes, palms, soles
Triggered by HSV, PCN, Sulfa, NSAIDS
!TEN/SJS
Do an RPR to r/o syphilis

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4
Q

Steven Johnson Syndrome (SJS) keywords

A

Basal cell degeneration

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5
Q

Toxic Epidermal Necrolysis (TEN) keywords

A

Epidermal Eosinophils

>30%

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6
Q

Erythema Nodosum description
Triggers
Diagnostic considerations

A

Painful erythematous lower leg nodules
Triggered by Strep, Coccidiodes, TB, Sulfa, Sarcoid, Crohn’s UC, Behcet’s
Rule out the triggers above (ASO, PPD, CXR for sarcoid, Bowel series). May see False +VDRL

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7
Q

Bullous Pemphigoid keywords

A

IgG + C3 anti-Hemidesmosomes on basement membrane
Tense
Prednisone tx.

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8
Q

Pemphigus Vulgaris (vulgar=bad)

A
IgG Anti-Desmosomes
Flaccid
\+ Nikolsky
Tombstoning
Prednisone + IVIg, MMF, Rituximab, AZA, MTX tx.
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9
Q

Genital Warts keywords

A

HPV 16 and 18

Tx: Freezing, Podophyllin, Trichloroacetic acid, Imiquimod, 5FU

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10
Q

Scarlet Fever keywords

A

Strep pyogenes
sunburn + goosebumps
strawberry tongue
Tx. PCN

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11
Q

Salmonella Typhi keywords

A

Pink rose spots on trunk

Tx. Fluoroquinolones and Ceftriaxone

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12
Q

Ludwig’s angina

A

Cellulitis of submental/maxillary/lingual space from infected tooth

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13
Q

Most common causes of necrotizing fasciitis

Medical tx.

A
Strep pyogenes (10%)
Staph aureus + E. coli + Clostridium perfringens

PCN, Clindamycin, Metronidazole/Ceftriaxone

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14
Q

Fournier gangrene

A

genital and perineal necrotizing fasciitis

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15
Q

Isoretinoin
Indications
Complications

A

for severe cystic acne

teratogenic, ^ LFTs, ^ chol, ^ TGs, worsen depression

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16
Q

Most likely side effect of Transretinoin

A

excessive dryness and skin peeling

17
Q

Tinea Versicolor description
Pathogen
Tx

A

HyPO/HyPER-pigmented scaly patches “spaghetti and meatballs”
Malassezia furfur/Pityrosporum orbiculare

Ketoconazole 2% or Selenium Sulfide topical

18
Q

Scabies keywords

Tx

A

night time post-shower pruritus
linear pimples betwen knuckles, axilla

5% Permethrin from the neck down for pts. AND partners

19
Q

Rosacea keywords

Tx

A

facial erythema + telangiectasias

Metronidazole

20
Q

What is actinic keratosis a precursor of?

Tx?

A

SCC

Topical 5FU

21
Q

Basal Cell ca. keywords

A

upper face (above the lip)
UV sun exposure
palisading outer layer

22
Q

SCC keywords

A

sun exposure (below the lip)
keratin pearls
heaped up margins

23
Q
Mycosis Fungoides (Cutaneous T-cell Lymphoma)
Tx
A

Cerebriform lymphocytes/Sezary cells

Phototherapy

24
Q

Leprosy keywords

Pathogen

A

Carbol fuchsin stian
Peripheral n. damage

Mycobacterium Leprae (G+R, acid fast)

25
Vasospastic ulcers
small, dry, painful, no pulses d/t vasospastic process like Raynaud's
26
Venous insufficiency ulcers most common location
medial malleolus
27
Livedo reticularis is generally a symptom of what disease?
Cholesterol embolization
28
What would you see in the eyes of someone with cholesterol embolization?
Hollenhorst plaques in retinal a.'s
29
Melanocytes are derived from what kind of cells? What is a marker for melanoma?
Neural crest cells S100
30
Most common AE of oral Tetracyclines (Minocycline)
Photosensitivity Tetracyclines are contraindicated in pregnancy d/t risk of abnormal fetal bone development and tooth discoloration.
31
Vitiligo d/t dx tx
Autoimmune melanocyte destruction May be assoc. with other autoimmune disorders (thyroid disease, DM) so Dx: check TSH and Fasting Blood Glucose Tx: phototherapy, laser therapy
32
Trichophyton dermatophyte keywords
well circumscribed scaly and pruritic lesions Tx: Ketoconazole, Terbinafine, Miconazole