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Flashcards in Derm Deck (32):
1

Psoriasis keywords

Extensors
Onycholysis
Auspitz
Munro's microabscess (Neutrophils in stratum corneum)

2

What is onycholysis and what disease process are you likely to see it in?

Separation of nail from nail bed (white area of nail plate getting bigger)

3

Erythema Multiforme description
Triggers
Complications
Diagnostic considerations

Erythematous Targetoid lesions on mucous membranes, palms, soles
Triggered by HSV, PCN, Sulfa, NSAIDS
!TEN/SJS
Do an RPR to r/o syphilis

4

Steven Johnson Syndrome (SJS) keywords

Basal cell degeneration

5

Toxic Epidermal Necrolysis (TEN) keywords

Epidermal Eosinophils
>30%

6

Erythema Nodosum description
Triggers
Diagnostic considerations

Painful erythematous lower leg nodules
Triggered by Strep, Coccidiodes, TB, Sulfa, Sarcoid, Crohn's UC, Behcet's
Rule out the triggers above (ASO, PPD, CXR for sarcoid, Bowel series). May see False +VDRL

7

Bullous Pemphigoid keywords

IgG + C3 anti-Hemidesmosomes on basement membrane
Tense
Prednisone tx.

8

Pemphigus Vulgaris (vulgar=bad)

IgG Anti-Desmosomes
Flaccid
+ Nikolsky
Tombstoning
Prednisone + IVIg, MMF, Rituximab, AZA, MTX tx.

9

Genital Warts keywords

HPV 16 and 18
Tx: Freezing, Podophyllin, Trichloroacetic acid, Imiquimod, 5FU

10

Scarlet Fever keywords

Strep pyogenes
sunburn + goosebumps
strawberry tongue
Tx. PCN

11

Salmonella Typhi keywords

Pink rose spots on trunk
Tx. Fluoroquinolones and Ceftriaxone

12

Ludwig's angina

Cellulitis of submental/maxillary/lingual space from infected tooth

13

Most common causes of necrotizing fasciitis

Medical tx.

Strep pyogenes (10%)
Staph aureus + E. coli + Clostridium perfringens

PCN, Clindamycin, Metronidazole/Ceftriaxone

14

Fournier gangrene

genital and perineal necrotizing fasciitis

15

Isoretinoin
Indications
Complications

for severe cystic acne

teratogenic, ^ LFTs, ^ chol, ^ TGs, worsen depression

16

Most likely side effect of Transretinoin

excessive dryness and skin peeling

17

Tinea Versicolor description
Pathogen
Tx

HyPO/HyPER-pigmented scaly patches "spaghetti and meatballs"
Malassezia furfur/Pityrosporum orbiculare

Ketoconazole 2% or Selenium Sulfide topical

18

Scabies keywords
Tx

night time post-shower pruritus
linear pimples betwen knuckles, axilla

5% Permethrin from the neck down for pts. AND partners

19

Rosacea keywords
Tx

facial erythema + telangiectasias

Metronidazole

20

What is actinic keratosis a precursor of?

Tx?

SCC

Topical 5FU

21

Basal Cell ca. keywords

upper face (above the lip)
UV sun exposure
palisading outer layer

22

SCC keywords

sun exposure (below the lip)
keratin pearls
heaped up margins

23

Mycosis Fungoides (Cutaneous T-cell Lymphoma)
Tx

Cerebriform lymphocytes/Sezary cells

Phototherapy

24

Leprosy keywords
Pathogen

Carbol fuchsin stian
Peripheral n. damage

Mycobacterium Leprae (G+R, acid fast)

25

Vasospastic ulcers

small, dry, painful, no pulses d/t vasospastic process like Raynaud's

26

Venous insufficiency ulcers most common location

medial malleolus

27

Livedo reticularis is generally a symptom of what disease?

Cholesterol embolization

28

What would you see in the eyes of someone with cholesterol embolization?

Hollenhorst plaques in retinal a.'s

29

Melanocytes are derived from what kind of cells? What is a marker for melanoma?

Neural crest cells

S100

30

Most common AE of oral Tetracyclines (Minocycline)

Photosensitivity

Tetracyclines are contraindicated in pregnancy d/t risk of abnormal fetal bone development and tooth discoloration.

31

Vitiligo

d/t

dx

tx

Autoimmune melanocyte destruction

May be assoc. with other autoimmune disorders (thyroid disease, DM) so
Dx: check TSH and Fasting Blood Glucose

Tx: phototherapy, laser therapy

32

Trichophyton dermatophyte keywords

well circumscribed
scaly and pruritic lesions

Tx: Ketoconazole, Terbinafine, Miconazole