connective tissue Flashcards

1
Q

what are the connective tissues?

A

blood, loose connective tissue, dense: bone, cartilage, tendon, ligaments

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2
Q

what is cell origin of ct

A

mesenchyme/mesoderm

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3
Q

loose connective tissue made of

A

fibroblasts, extracellular matrix (collagen and elastin fibers, fibronectin, laminin, ground substance)

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4
Q

ground substance

A

chains of glycosaminoglycans (GAGs) which hold water to reduce compressive force, proteoglycan complexed with - ions to also attract water, has core protein and chondroitin sulfate side chains. 90% of mass, 10% of weight. fills space

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5
Q

fibroblasts

A

secrete ground substance

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6
Q

GAG example

A

hyaluronic acid

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7
Q

adipocytes

A

fat-producing cells, starts as undifferentiated fibroblasts (mesenchyme, could form osteoblasts or myocytes as well)

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8
Q

Collagen (with types)

A

cross-linked chains.
1= large, used in dermis, bones, tendons,
2- not fibrous, used in hyaline cartilage
3= small fibers. arteries and muscles
4- found in skin
5- skin and hair

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9
Q

tendons vs ligaments

A

tendons attach muscle to bone, ligaments straddle joints. both made of collagen 1, few fibroblasts and little blood, tendons are more structured but ligaments less organized.

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10
Q

elastin is part of..

A

made of crosslinked fibers, makes up aorta, lungs, bladder, elastic cartilage, skin

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11
Q

cartilage is made of..

A

lacunae with chondrocytes which secrete ECM (type 2 collagen and extra - charged ground substance for max compression resistance). outer layer is dense perichondrium made of type 1 and fibroblasts

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12
Q

hyaline cartilage

A

made of type 2, cushions joints, trachaea, nasal cartilage

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13
Q

fibrocartilage makes up..

A

intervertebral disks, pelvic girdle (lots of collagen)

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14
Q

elastic cartilage makes up..

A

ear, epiglottis

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15
Q

calcified cartilage is found..

A

in vertebrae of chondrichthyes

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16
Q

intermembranous ossification forms..

A

skull and clavicle (dermato)

17
Q

how does endochondral bone form?

A

osteoclasts eat away cartilage, blood enters, osteoblasts form structure (from diaphysis to epiphysis). bone forms in islands. ends stay cartilaginous

18
Q

structure inside of bone

A

canaliculae - small channels for cells to communicate, haversian canal - holds blood vessels and nerves, ground substance in bone (secreted by osteoblasts) is osteioid. it is 65% mineral, 25% collagen 1

19
Q

lacuna

A

cavity in bone made by vacated osteocyte

20
Q

joint types

A

synarthroses (restricted movement, like skull) vs diarthroses (articulated)

21
Q

spicules

A

areas of growth

22
Q

osteon

A

a unit surrounding haversian canal

23
Q

lamella

A

layer of mineral deposit

24
Q

epiphyseal plate

A

growth plate of bone which remains cartilaginous upon ossification.

25
Q

intramembranous ossification shows..

A

head emerged as a new feature, bc it is bone before the rest of the body is.

26
Q

diaphysis

A

middle of bone (as opposed to ends)

27
Q

chondroitin sulfate

A

one of the building blocks of cartilage